Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945404445> ?p ?o ?g. }
- W2945404445 endingPage "108979" @default.
- W2945404445 startingPage "108979" @default.
- W2945404445 abstract "Great efforts have been made to explore the potential treatment for cancers, and the most common therapies include surgery, chemotherapy and radiotherapy. As an alternative medication, earthworms have drawn increased attention considering its abundance in resource, easy access and minor side effects compared to traditional therapies. However, few studies had focused on the antitumor effect of earthworm-derived components. The purpose of this study is to investigate whether earthworm extract has an effect on tumor cell apoptosis and growth. Earthworm extract (EE) was purified through multiple steps of centrifugation and chromatography. Mice were inoculated with ascitic fluid derived from mice inoculated with S180 sarcoma tumor cells and fed orally with different amounts of EE for 25 days. Tumor samples were analyzed for size and cell apoptosis. And we found that the weight and sizes of tumor decreased gradually as the amount of EE administered increased. More apoptotic cells and lowered level of lactate dehydrogenase (LDH), a biomarker of tumor invasiveness, was detected in EE-treated group than the untreated group. Our results suggested that EE could dramatically promote tumor apoptosis and reduce tumor size in vivo, suggesting a novel alternative therapy for cancer patients." @default.
- W2945404445 created "2019-05-29" @default.
- W2945404445 creator A5007277206 @default.
- W2945404445 creator A5033709305 @default.
- W2945404445 creator A5051156999 @default.
- W2945404445 creator A5054566597 @default.
- W2945404445 creator A5055232454 @default.
- W2945404445 creator A5066071162 @default.
- W2945404445 creator A5087671347 @default.
- W2945404445 date "2019-07-01" @default.
- W2945404445 modified "2023-10-14" @default.
- W2945404445 title "The effect of earthworm extract on mice S180 tumor growth and apoptosis" @default.
- W2945404445 cites W1574675143 @default.
- W2945404445 cites W1580503774 @default.
- W2945404445 cites W1954185000 @default.
- W2945404445 cites W1964959571 @default.
- W2945404445 cites W1966761325 @default.
- W2945404445 cites W1973740064 @default.
- W2945404445 cites W1974165723 @default.
- W2945404445 cites W1974453724 @default.
- W2945404445 cites W2000287188 @default.
- W2945404445 cites W2008757142 @default.
- W2945404445 cites W2009183786 @default.
- W2945404445 cites W2022803736 @default.
- W2945404445 cites W2031771562 @default.
- W2945404445 cites W2081211388 @default.
- W2945404445 cites W2086159781 @default.
- W2945404445 cites W2097259163 @default.
- W2945404445 cites W2142141154 @default.
- W2945404445 cites W2144515961 @default.
- W2945404445 cites W2149072971 @default.
- W2945404445 cites W2157377207 @default.
- W2945404445 cites W2159078978 @default.
- W2945404445 cites W2192523698 @default.
- W2945404445 cites W2197167222 @default.
- W2945404445 cites W2281692823 @default.
- W2945404445 cites W2404428172 @default.
- W2945404445 cites W2414938589 @default.
- W2945404445 cites W2530783620 @default.
- W2945404445 cites W2532408015 @default.
- W2945404445 cites W2570618306 @default.
- W2945404445 cites W2598922954 @default.
- W2945404445 cites W2619853619 @default.
- W2945404445 cites W2744010673 @default.
- W2945404445 cites W2751623946 @default.
- W2945404445 cites W2774930046 @default.
- W2945404445 cites W2778920259 @default.
- W2945404445 cites W2791907949 @default.
- W2945404445 cites W2795826058 @default.
- W2945404445 cites W2806761003 @default.
- W2945404445 doi "https://doi.org/10.1016/j.biopha.2019.108979" @default.
- W2945404445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31100538" @default.
- W2945404445 hasPublicationYear "2019" @default.
- W2945404445 type Work @default.
- W2945404445 sameAs 2945404445 @default.
- W2945404445 citedByCount "8" @default.
- W2945404445 countsByYear W29454044452019 @default.
- W2945404445 countsByYear W29454044452020 @default.
- W2945404445 countsByYear W29454044452021 @default.
- W2945404445 countsByYear W29454044452022 @default.
- W2945404445 countsByYear W29454044452023 @default.
- W2945404445 crossrefType "journal-article" @default.
- W2945404445 hasAuthorship W2945404445A5007277206 @default.
- W2945404445 hasAuthorship W2945404445A5033709305 @default.
- W2945404445 hasAuthorship W2945404445A5051156999 @default.
- W2945404445 hasAuthorship W2945404445A5054566597 @default.
- W2945404445 hasAuthorship W2945404445A5055232454 @default.
- W2945404445 hasAuthorship W2945404445A5066071162 @default.
- W2945404445 hasAuthorship W2945404445A5087671347 @default.
- W2945404445 hasBestOaLocation W29454044451 @default.
- W2945404445 hasConcept C126322002 @default.
- W2945404445 hasConcept C1491633281 @default.
- W2945404445 hasConcept C150903083 @default.
- W2945404445 hasConcept C151730666 @default.
- W2945404445 hasConcept C180032290 @default.
- W2945404445 hasConcept C181199279 @default.
- W2945404445 hasConcept C190283241 @default.
- W2945404445 hasConcept C203014093 @default.
- W2945404445 hasConcept C207001950 @default.
- W2945404445 hasConcept C2776332788 @default.
- W2945404445 hasConcept C2776694085 @default.
- W2945404445 hasConcept C2777318727 @default.
- W2945404445 hasConcept C29537977 @default.
- W2945404445 hasConcept C502942594 @default.
- W2945404445 hasConcept C509974204 @default.
- W2945404445 hasConcept C55493867 @default.
- W2945404445 hasConcept C71924100 @default.
- W2945404445 hasConcept C86803240 @default.
- W2945404445 hasConcept C98274493 @default.
- W2945404445 hasConceptScore W2945404445C126322002 @default.
- W2945404445 hasConceptScore W2945404445C1491633281 @default.
- W2945404445 hasConceptScore W2945404445C150903083 @default.
- W2945404445 hasConceptScore W2945404445C151730666 @default.
- W2945404445 hasConceptScore W2945404445C180032290 @default.
- W2945404445 hasConceptScore W2945404445C181199279 @default.
- W2945404445 hasConceptScore W2945404445C190283241 @default.
- W2945404445 hasConceptScore W2945404445C203014093 @default.
- W2945404445 hasConceptScore W2945404445C207001950 @default.