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• W2945437818 endingPage "1320" @default.
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• W2945437818 abstract "A patient with Korsakoff syndrome of psychiatric and alcoholic etiology presenting as DSM-5 mild neurocognitive disorder Georgios Nikolakaros,1,2 Timo Kurki,3,4 Arttu Myllymäki,1 Tuula Ilonen51Satakunta Hospital District, Psychiatric Care Division, General Psychiatry Outpatient Clinic, Pori, Finland; 2HUS Medical Imaging Center, Department of Clinical Neurophysiology, Helsinki University Hospital, Helsinki, Finland; 3Terveystalo Pulssi Medical Center, Turku, Finland; 4Department of Radiology, University of Turku, Turku, Finland; 5Department of Psychiatry, University of Turku, Turku, FinlandBackground: Wernicke’s encephalopathy (WE) and Korsakoff syndrome (KS) are underdiagnosed. The DSM-5 has raised the diagnostic threshold by including KS in the major neurocognitive disorders, which requires that the patient needs help in everyday activities.Methods: We report clinical, neuropsychological, and radiological findings from a patient who developed Wernicke-Korsakoff syndrome as a result of alcohol use and weight loss due to major depression. We assess the diagnosis in the context of the scientific literature on KS and according to the DSM-IV and the DSM-5.Results: The patient developed ataxia during a period of weight loss, thus fulfilling current diagnostic criteria of WE. WE was not diagnosed, but the patient partially improved after parenteral thiamine treatment. However, memory problems became evident, and KS was considered. In neuropsychological examination, the Logical Memory test and the Word List test were abnormal, but the Verbal Pair Associates test was normal (Wechsler Memory Scale-III). There were intrusions in the memory testing. The Wisconsin Card Sorting Test was broadly impaired, but the other test of executive functions (difference between Trail Making B and Trail Making A tests) was normal. There was atrophy of the mammillary bodies, the thalamus, the cerebellum, and in the basal ganglia but not in the frontal lobes. Diffusion tensor imaging showed damage in several tracts, including the uncinate fasciculi, the cinguli, the fornix, and the corona radiata. The patient remained independent in everyday activities. The patient can be diagnosed with KS according to the DSM-IV. According to the DSM-5, the patient has major neurocognitive disorders.Conclusions: Extensive memory testing is essential in the assessment of KS. Patients with a history of WE and typical clinical, neuropsychological, and radiological KS findings may be independent in everyday activities. Strict use of the DSM-5 may worsen the problem of Wernicke-Korsakoff syndrome underdiagnosis by excluding clear KS cases that do not have very severe functional impairment.Keywords: alcoholism, depressive disorder, diffusion tensor imaging, Korsakoff syndrome, neurocognitive disorders, Wernicke encephalopathy" @default.
• W2945437818 created "2019-05-29" @default.
• W2945437818 creator A5019494039 @default.
• W2945437818 creator A5035833037 @default.
• W2945437818 creator A5052013965 @default.
• W2945437818 creator A5073884500 @default.
• W2945437818 date "2019-05-01" @default.
• W2945437818 modified "2023-10-14" @default.
• W2945437818 title "<p>A patient with Korsakoff syndrome of psychiatric and alcoholic etiology presenting as DSM-5 mild neurocognitive disorder</p>" @default.
• W2945437818 cites W1551942315 @default.
• W2945437818 cites W1629261688 @default.
• W2945437818 cites W1968956567 @default.
• W2945437818 cites W1971141009 @default.
• W2945437818 cites W1974034298 @default.
• W2945437818 cites W1980427595 @default.
• W2945437818 cites W1983392889 @default.
• W2945437818 cites W1989571276 @default.
• W2945437818 cites W1994099614 @default.
• W2945437818 cites W2002809129 @default.
• W2945437818 cites W2004071694 @default.
• W2945437818 cites W2004185482 @default.
• W2945437818 cites W2004742176 @default.
• W2945437818 cites W2004791667 @default.
• W2945437818 cites W2011279475 @default.
• W2945437818 cites W2013237260 @default.
• W2945437818 cites W2017908583 @default.
• W2945437818 cites W2020961187 @default.
• W2945437818 cites W2021502601 @default.
• W2945437818 cites W2022844625 @default.
• W2945437818 cites W2026655072 @default.
• W2945437818 cites W2029597876 @default.
• W2945437818 cites W2034395677 @default.
• W2945437818 cites W2035134077 @default.
• W2945437818 cites W2040320466 @default.
• W2945437818 cites W2050662858 @default.
• W2945437818 cites W2065968104 @default.
• W2945437818 cites W2066001391 @default.
• W2945437818 cites W2072158650 @default.
• W2945437818 cites W2072528158 @default.
• W2945437818 cites W2072868947 @default.
• W2945437818 cites W2075708727 @default.
• W2945437818 cites W2079095678 @default.
• W2945437818 cites W2082932894 @default.
• W2945437818 cites W2089952488 @default.
• W2945437818 cites W2091912793 @default.
• W2945437818 cites W2100993141 @default.
• W2945437818 cites W2104445595 @default.
• W2945437818 cites W2106711803 @default.
• W2945437818 cites W2111592519 @default.
• W2945437818 cites W2124490687 @default.
• W2945437818 cites W2126627235 @default.
• W2945437818 cites W2127902263 @default.
• W2945437818 cites W2134369415 @default.
• W2945437818 cites W2141962866 @default.
• W2945437818 cites W2144755357 @default.
• W2945437818 cites W2147981073 @default.
• W2945437818 cites W2151132164 @default.
• W2945437818 cites W2153866566 @default.
• W2945437818 cites W2163988477 @default.
• W2945437818 cites W2164073272 @default.
• W2945437818 cites W2167165218 @default.
• W2945437818 cites W2168903842 @default.
• W2945437818 cites W2234123570 @default.
• W2945437818 cites W2289251924 @default.
• W2945437818 cites W2316620852 @default.
• W2945437818 cites W2319079614 @default.
• W2945437818 cites W2328686686 @default.
• W2945437818 cites W2399477521 @default.
• W2945437818 cites W2406664973 @default.
• W2945437818 cites W2444550124 @default.
• W2945437818 cites W2508968273 @default.
• W2945437818 cites W2520041858 @default.
• W2945437818 cites W2522263602 @default.
• W2945437818 cites W2564091276 @default.
• W2945437818 cites W2573321646 @default.
• W2945437818 cites W2593431579 @default.
• W2945437818 cites W2606135318 @default.
• W2945437818 cites W264401500 @default.
• W2945437818 cites W2769955740 @default.
• W2945437818 cites W2793350532 @default.
• W2945437818 cites W2803058272 @default.
• W2945437818 cites W2911324150 @default.
• W2945437818 cites W2952216018 @default.
• W2945437818 cites W4236362414 @default.
• W2945437818 cites W4253551398 @default.
• W2945437818 doi "https://doi.org/10.2147/ndt.s203513" @default.
• W2945437818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6535456" @default.
• W2945437818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31190835" @default.
• W2945437818 hasPublicationYear "2019" @default.
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