Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945444375> ?p ?o ?g. }
- W2945444375 endingPage "527" @default.
- W2945444375 startingPage "517" @default.
- W2945444375 abstract "Aim: To evaluate the influence of genetic polymorphisms on plasma trough concentrations of atazanavir (ATV) and ritonavir (RTV). Patients & methods: The concentration-to-dose ratios were compared between different genotype groups of CYP3A5, ABCB1, SLCO1B1 and NR1I2 in 490 patients. Multiple regression analysis was used to examine the association between genetic and clinical factors and log-transformed concentration-to-dose ratio of ATV and RTV. Results: Higher concentrations of ATV and RTV were significantly associated with CYP3A5 6986 GG and SLCO1B1 521 TC or CC. Female patients had significantly higher ATV plasma concentration than male patients. Conclusion: Genetic polymorphisms and gender are factors affecting the variability of ATV and RTV concentrations in the Thai population. Thus, genetic testing is worth considering when atazanavir + low dose ritonavir is prescribed." @default.
- W2945444375 created "2019-05-29" @default.
- W2945444375 creator A5021568119 @default.
- W2945444375 creator A5028932019 @default.
- W2945444375 creator A5030905646 @default.
- W2945444375 creator A5038477640 @default.
- W2945444375 creator A5039945360 @default.
- W2945444375 creator A5042629578 @default.
- W2945444375 creator A5051259565 @default.
- W2945444375 creator A5056483150 @default.
- W2945444375 creator A5081087840 @default.
- W2945444375 creator A5086641466 @default.
- W2945444375 date "2019-05-01" @default.
- W2945444375 modified "2023-09-24" @default.
- W2945444375 title "Influence of CYP3A5 and SLCO1B1 polymorphisms on atazanavir/r concentrations in Thai HIV-infected patients" @default.
- W2945444375 cites W1963760050 @default.
- W2945444375 cites W1964298239 @default.
- W2945444375 cites W1964622173 @default.
- W2945444375 cites W1967167318 @default.
- W2945444375 cites W1987351366 @default.
- W2945444375 cites W1996364592 @default.
- W2945444375 cites W1999160932 @default.
- W2945444375 cites W2006648763 @default.
- W2945444375 cites W2014762236 @default.
- W2945444375 cites W2028731404 @default.
- W2945444375 cites W2034972283 @default.
- W2945444375 cites W2035462276 @default.
- W2945444375 cites W2037975995 @default.
- W2945444375 cites W2040745732 @default.
- W2945444375 cites W2050617356 @default.
- W2945444375 cites W2059158540 @default.
- W2945444375 cites W2066731188 @default.
- W2945444375 cites W2067831264 @default.
- W2945444375 cites W2072666308 @default.
- W2945444375 cites W2081752205 @default.
- W2945444375 cites W2099015360 @default.
- W2945444375 cites W2099629087 @default.
- W2945444375 cites W2101314083 @default.
- W2945444375 cites W2102046578 @default.
- W2945444375 cites W2103478173 @default.
- W2945444375 cites W2106044342 @default.
- W2945444375 cites W2112306615 @default.
- W2945444375 cites W2113719939 @default.
- W2945444375 cites W2117312836 @default.
- W2945444375 cites W2119239704 @default.
- W2945444375 cites W2122309081 @default.
- W2945444375 cites W2122443477 @default.
- W2945444375 cites W2130445803 @default.
- W2945444375 cites W2145044292 @default.
- W2945444375 cites W2145580268 @default.
- W2945444375 cites W2152217749 @default.
- W2945444375 cites W2154345245 @default.
- W2945444375 cites W2155931959 @default.
- W2945444375 cites W2158254598 @default.
- W2945444375 cites W2161427131 @default.
- W2945444375 cites W2168369403 @default.
- W2945444375 cites W2256104905 @default.
- W2945444375 cites W2260167533 @default.
- W2945444375 cites W2321368561 @default.
- W2945444375 cites W2321921869 @default.
- W2945444375 cites W2347802084 @default.
- W2945444375 cites W2400954745 @default.
- W2945444375 cites W2410226431 @default.
- W2945444375 cites W2518959531 @default.
- W2945444375 cites W2576099434 @default.
- W2945444375 cites W4252913081 @default.
- W2945444375 doi "https://doi.org/10.2217/pgs-2018-0196" @default.
- W2945444375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31124411" @default.
- W2945444375 hasPublicationYear "2019" @default.
- W2945444375 type Work @default.
- W2945444375 sameAs 2945444375 @default.
- W2945444375 citedByCount "4" @default.
- W2945444375 countsByYear W29454443752021 @default.
- W2945444375 countsByYear W29454443752022 @default.
- W2945444375 crossrefType "journal-article" @default.
- W2945444375 hasAuthorship W2945444375A5021568119 @default.
- W2945444375 hasAuthorship W2945444375A5028932019 @default.
- W2945444375 hasAuthorship W2945444375A5030905646 @default.
- W2945444375 hasAuthorship W2945444375A5038477640 @default.
- W2945444375 hasAuthorship W2945444375A5039945360 @default.
- W2945444375 hasAuthorship W2945444375A5042629578 @default.
- W2945444375 hasAuthorship W2945444375A5051259565 @default.
- W2945444375 hasAuthorship W2945444375A5056483150 @default.
- W2945444375 hasAuthorship W2945444375A5081087840 @default.
- W2945444375 hasAuthorship W2945444375A5086641466 @default.
- W2945444375 hasConcept C104317684 @default.
- W2945444375 hasConcept C126322002 @default.
- W2945444375 hasConcept C135763542 @default.
- W2945444375 hasConcept C142462285 @default.
- W2945444375 hasConcept C159047783 @default.
- W2945444375 hasConcept C2776598434 @default.
- W2945444375 hasConcept C2778414717 @default.
- W2945444375 hasConcept C2779298103 @default.
- W2945444375 hasConcept C2908647359 @default.
- W2945444375 hasConcept C2993143319 @default.
- W2945444375 hasConcept C3013748606 @default.
- W2945444375 hasConcept C3020079912 @default.
- W2945444375 hasConcept C54355233 @default.