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- W2945449319 abstract "This paper presents a mm-sized, free-floating, wirelessly powered, implantable optical stimulation (FF-WIOS) device for untethered optogenetic neuromodulation. A resonator-based three-coil inductive link creates a homogeneous magnetic field that continuously delivers sufficient power (>2.7 mW) at an optimal carrier frequency of 60 MHz to the FF-WIOS in the near field without surpassing the specific absorption rate limit, regardless of the position of the FF-WIOS in a large brain area. Forward data telemetry carries stimulation parameters by on-off-keying the power carrier at a data rate of 50 kb/s to selectively activate a 4 × 4 μLED array. Load-shift-keying back telemetry controls the wireless power transmission by reporting the FF-WIOS received power level in a closed-loop power control mechanism. LEDs typically require high instantaneous power to emit sufficient light for optical stimulation. Thus, a switched-capacitor-based stimulation architecture is used as an energy storage buffer with one off-chip capacitor to receive charge directly from the inductive link and deliver it to the selected μLED at the onset of stimulation. The FF-WIOS system-on-a-chip prototype, fabricated in a 0.35-μm standard CMOS process, charges a 10-μF capacitor up to 5 V with 37% efficiency and passes instantaneous current spikes up to 10 mA in the selected μLED, creating a bright exponentially decaying flash with minimal wasted power. An in vivo experiment was conducted to verify the efficacy of the FF-WIOS by observing light-evoked local field potentials and immunostained tissue response from the primary visual cortex (V1) of two anesthetized rats." @default.
- W2945449319 created "2019-05-29" @default.
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- W2945449319 date "2019-08-01" @default.
- W2945449319 modified "2023-10-14" @default.
- W2945449319 title "A mm-Sized Free-Floating Wirelessly Powered Implantable Optical Stimulation Device" @default.
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- W2945449319 doi "https://doi.org/10.1109/tbcas.2019.2918761" @default.
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