FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945479899> ?p ?o ?g. }

• W2945479899 abstract "The IL-1 cytokines are a newly expanded family, with each of its 11 members playing an important role in health and disease. Typically acting as pro- or anti-inflammatory mediators of first-line innate immunity, their production is particularly important in the context of mucosal defences, through handling breach of the delicate epithelial barrier and mediating a local immune response to invading pathogens. Mucosal immunity is often aberrantly orchestrated in intestinal diseases, such as Inflammatory Bowel Disease (IBD). Various studies have pointed to IL-1 cytokines as being important players in IBD with context-dependent roles, either through promoting auto-inflammatory mechanisms, or alleviating disease through protection against breach of pathogens across the epithelial barrier. This mini-review will succinctly examine the role of IL-1 family members in IBD, with a special focus on the recently described IL-33 as well as IL-18, and will explore the disease models within which these cytokines have been studied. Furthermore, we will examine the evidence of interplay of these cytokines with the gut microbiota, with hopes of summarising our current knowledge of these family members and their potential for unravelling novel molecular mechanisms of IBD pathology." @default.
• W2945479899 created "2019-05-29" @default.
• W2945479899 creator A5006242621 @default.
• W2945479899 creator A5051087379 @default.
• W2945479899 creator A5059279926 @default.
• W2945479899 date "2019-05-14" @default.
• W2945479899 modified "2023-10-17" @default.
• W2945479899 title "IL-33 and IL-18 in Inflammatory Bowel Disease Etiology and Microbial Interactions" @default.
• W2945479899 cites W1028422299 @default.
• W2945479899 cites W104930202 @default.
• W2945479899 cites W1587765254 @default.
• W2945479899 cites W1662827845 @default.
• W2945479899 cites W1795019646 @default.
• W2945479899 cites W1819325258 @default.
• W2945479899 cites W1899804292 @default.
• W2945479899 cites W1905805852 @default.
• W2945479899 cites W1968955229 @default.
• W2945479899 cites W1987257733 @default.
• W2945479899 cites W1999317689 @default.
• W2945479899 cites W2038894130 @default.
• W2945479899 cites W2042622445 @default.
• W2945479899 cites W2057190795 @default.
• W2945479899 cites W2067394439 @default.
• W2945479899 cites W2073666097 @default.
• W2945479899 cites W2075074747 @default.
• W2945479899 cites W2078489088 @default.
• W2945479899 cites W2084575069 @default.
• W2945479899 cites W2085375952 @default.
• W2945479899 cites W2087778794 @default.
• W2945479899 cites W2089794803 @default.
• W2945479899 cites W2093396768 @default.
• W2945479899 cites W2097568300 @default.
• W2945479899 cites W2098711659 @default.
• W2945479899 cites W2100091884 @default.
• W2945479899 cites W2100559322 @default.
• W2945479899 cites W2106855445 @default.
• W2945479899 cites W2108957588 @default.
• W2945479899 cites W2110115488 @default.
• W2945479899 cites W2112483272 @default.
• W2945479899 cites W2112802262 @default.
• W2945479899 cites W2121674630 @default.
• W2945479899 cites W2121693891 @default.
• W2945479899 cites W2127826178 @default.
• W2945479899 cites W2131180975 @default.
• W2945479899 cites W2157710399 @default.
• W2945479899 cites W2161926362 @default.
• W2945479899 cites W2167927725 @default.
• W2945479899 cites W2168452283 @default.
• W2945479899 cites W2184709292 @default.
• W2945479899 cites W2188593832 @default.
• W2945479899 cites W2278260231 @default.
• W2945479899 cites W2326397891 @default.
• W2945479899 cites W2535333181 @default.
• W2945479899 cites W2537632135 @default.
• W2945479899 cites W2594848814 @default.
• W2945479899 cites W2609398719 @default.
• W2945479899 cites W2609744794 @default.
• W2945479899 cites W2732876057 @default.
• W2945479899 cites W2735140936 @default.
• W2945479899 cites W2755294599 @default.
• W2945479899 cites W2795084096 @default.
• W2945479899 cites W2811315997 @default.
• W2945479899 cites W2890292757 @default.
• W2945479899 cites W2890485373 @default.
• W2945479899 cites W2890995777 @default.
• W2945479899 cites W2918150759 @default.
• W2945479899 doi "https://doi.org/10.3389/fimmu.2019.01091" @default.
• W2945479899 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6527769" @default.
• W2945479899 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31139196" @default.
• W2945479899 hasPublicationYear "2019" @default.
• W2945479899 type Work @default.
• W2945479899 sameAs 2945479899 @default.
• W2945479899 citedByCount "57" @default.
• W2945479899 countsByYear W29454798992020 @default.
• W2945479899 countsByYear W29454798992021 @default.
• W2945479899 countsByYear W29454798992022 @default.
• W2945479899 countsByYear W29454798992023 @default.
• W2945479899 crossrefType "journal-article" @default.
• W2945479899 hasAuthorship W2945479899A5006242621 @default.
• W2945479899 hasAuthorship W2945479899A5051087379 @default.
• W2945479899 hasAuthorship W2945479899A5059279926 @default.
• W2945479899 hasBestOaLocation W29454798991 @default.
• W2945479899 hasConcept C136449434 @default.
• W2945479899 hasConcept C142724271 @default.
• W2945479899 hasConcept C151730666 @default.
• W2945479899 hasConcept C164027704 @default.
• W2945479899 hasConcept C203014093 @default.
• W2945479899 hasConcept C2776914184 @default.
• W2945479899 hasConcept C2778260677 @default.
• W2945479899 hasConcept C2779134260 @default.
• W2945479899 hasConcept C2779341262 @default.
• W2945479899 hasConcept C2779343474 @default.
• W2945479899 hasConcept C539455810 @default.
• W2945479899 hasConcept C71924100 @default.
• W2945479899 hasConcept C86803240 @default.
• W2945479899 hasConcept C8891405 @default.
• W2945479899 hasConceptScore W2945479899C136449434 @default.
• W2945479899 hasConceptScore W2945479899C142724271 @default.
• W2945479899 hasConceptScore W2945479899C151730666 @default.
• W2945479899 hasConceptScore W2945479899C164027704 @default.

• next