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- W2945492008 abstract "Abstract Although considerable efforts have been made to understand the neural underpinnings of (state) reactive aggression, which is triggered by provocation or perceived threat, little is known about the neural correlates of proactive aggression, which is driven by instrumental motivations to obtain personal gains through aggressive means and which varies dramatically across individuals in terms of tendency of appealing to such means. Here, by combining structural (grey matter density, GMD) and functional (resting-state functional connection, RSFC) fMRI, we investigated brain structures and functional networks related to trait proactive aggression. We found that individual differences in trait proactive aggression were positively associated with GMD in bilateral dorsolateral prefrontal cortex (DLPFC) and negatively correlated with GMD in posterior cingulate cortex (PCC); they were also negatively correlated with the strength of functional connectivity between left PCC and other brain regions, including right DLPFC, right IPL, right MPFC/ACC, and bilateral precuneus. These findings shed light on the differential brain bases of proactive and reactive aggressions and suggested the neural underpinnings of proactive aggression." @default.
- W2945492008 created "2019-05-29" @default.
- W2945492008 creator A5008047568 @default.
- W2945492008 creator A5073847180 @default.
- W2945492008 creator A5086507934 @default.
- W2945492008 date "2019-05-22" @default.
- W2945492008 modified "2023-10-16" @default.
- W2945492008 title "Brain structures and functional connectivity associated with individual differences in trait proactive aggression" @default.
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- W2945492008 doi "https://doi.org/10.1038/s41598-019-44115-4" @default.
- W2945492008 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6531458" @default.
- W2945492008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31118455" @default.
- W2945492008 hasPublicationYear "2019" @default.
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