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- W2945558081 abstract "The aim of this report is to summarize the clinical and laboratory effect and possible side-effects arising in the use of FEIBA IMMUNO for treating Factor VIII and IX inhibitor patients. In the time between 22nd November 1974 and today FEIBA IMMUNO was supplied for 104 treatment periods. More than 70 patients in 22 hemophilia centers all over Europe were treated, 59 case reports from 19 of the centers were sent to IMMUNO AG for further evaluation. In 8 cases minor surgery was carried out, of which only one case was complicated by post-operative bleeding. In all other cases different bleeding complications were treated. The clinical effect was difficult to evaluate, but the impression was favourable. FEIBA’s effect on WBCT, the r-value of TEG, and on aPTT are statistically evaluated for two different mean dosages. Acute side-effects were allergic reactions in 5 cases and laboratory signs of DIC in 4 cases, two of which had received extremely high dosages. Calculation of the mean pre- and post-treatment values for platelets and fibrinogen did not show any differences." @default.
- W2945558081 created "2019-05-29" @default.
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- W2945558081 date "1977-01-01" @default.
- W2945558081 modified "2023-09-23" @default.
- W2945558081 title "The Clinical Application of Feiba Immuno in Factor VIII Inhibitor Patients" @default.
- W2945558081 doi "https://doi.org/10.1055/s-0039-1682502" @default.
- W2945558081 hasPublicationYear "1977" @default.
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