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- W2945582509 endingPage "79" @default.
- W2945582509 startingPage "71" @default.
- W2945582509 abstract "Metabolic reprogramming as well as the flexible utilisation of fuel sources by tumour cells has been considered not only intrinsic to malignant cells but also sustained by resident and/or recruited stromal cells. The complexity of tumour-stroma cross-talk is experienced by neoplastic cells through profound changes in the own metabolic machinery. In such context, mitochondria are dynamic organelles that receive, orchestrate and exchange a multiplicity of stromal cues within the tumour cells to finely regulate key metabolic and signalling pathways, allowing malignant cells to adapt and thrive in an ever-changing environment. In this review, we focus on how tumour mitochondria are coached by stromal metabolic supply and how this re-education sustains tumour malignant traits." @default.
- W2945582509 created "2019-05-29" @default.
- W2945582509 creator A5022895279 @default.
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- W2945582509 creator A5039556730 @default.
- W2945582509 creator A5051823746 @default.
- W2945582509 creator A5079252504 @default.
- W2945582509 date "2020-02-01" @default.
- W2945582509 modified "2023-10-08" @default.
- W2945582509 title "Stromal-induced mitochondrial re-education: Impact on epithelial-to-mesenchymal transition and cancer aggressiveness" @default.
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- W2945582509 doi "https://doi.org/10.1016/j.semcdb.2019.05.009" @default.
- W2945582509 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31108187" @default.
- W2945582509 hasPublicationYear "2020" @default.
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