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• W2945588037 abstract "Abstract Objective: Both vitamin D and Fe micronutrient deficiencies are common in Saudi Arabia but the association between them is unclear. The present study aimed to determine whether Fe indices are associated with vitamin D status and other metabolic markers in Arab adolescents. Design: Single-centre, cross-sectional study gathering anthropometrics, glucose and lipid profile. Serum 25-hydroxyvitamin D (25(OH)D), Fe, total iron-binding capacity (TIBC), transferrin saturation (%) and other parameters were measured. Setting: Vitamin D School Project Database, King Saud University (2014–2016). Participants: Arab adolescents aged 10–17 years randomly selected from the Vitamin D School Project Database (170 Saudi students; 100 girls, seventy boys). Results: Among Fe indices, only TIBC was found to be significantly and inversely associated with 25(OH)D ( r = −0·20; P < 0·01) and only in girls ( r = −0·20; P < 0·05). Among cardiometabolic parameters, serum Fe was associated with TAG in boys ( r = 0·36; P < 0·01) and inversely associated with HDL-cholesterol in girls ( r = −0·29; P < 0·05). Age was the most significant predictor of serum Fe for all participants, accounting for 5 % ( R 2 = 0·05; P = 0·004) of variance perceived. Serum 25(OH)D and age, on the other hand, were the most significant predictors for TIBC, accounting for 10·1 % ( R 2 = 0·10; P < 0·001) of variance perceived. Conclusions: Among healthy Arab adolescents, the association between vitamin D and Fe indices, particularly TIBC, is modest, inverse and sex-dependent. Larger studies with inclusion of markers such as hepcidin and ferritin, vitamin D metabolites and endogenous sex hormones may provide a clearer view of this complex association." @default.
• W2945588037 created "2019-05-29" @default.
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• W2945588037 date "2019-05-17" @default.
• W2945588037 modified "2023-09-27" @default.
• W2945588037 title "The association between iron and vitamin D status in Arab adolescents" @default.
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• W2945588037 doi "https://doi.org/10.1017/s1368980019001113" @default.
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