FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945598921> ?p ?o ?g. }

• W2945598921 abstract "Recent studies suggest that delayed cord clamping (DCC) is advantageous for achieving hemodynamic stability and improving oxygenation compared to the immediate cord clamping (ICC) during fetal-to-neonatal transition yet there is no quantitative information on hemodynamics and respiration, particularly for pre-term babies and fetal disease states. Therefore, the objective of this study is to investigate the effects of ICC and DCC on hemodynamics and respiration of the newborn preterm infants in the presence of common vascular pathologies. A computational lumped parameter model (LPM) of the placental and respiratory system of a fetus is developed to predict blood pressure, flow rates and oxygen saturation. Cardiovascular system at different gestational ages (GA) are modeled using scaling relations governing fetal growth with the LPM. Intrauterine growth restriction (GR), patent ductus arteriosus (PDA) and respiratory distress syndrome (RDS) were modeled for a newborn at 30 weeks GA. We also formulated a “severity index (SI)” which is a weighted measure of ICC vs. DCC based on the functional parameters derived from our model and existing neonatal disease scoring systems. Our results show that transitional hemodynamics is smoother in DCC compared to ICC for all GAs. Blood volume of the neonate increases by 10% for moderately preterm and term infants (32–40 wks) and by 15% for very and extremely preterm infants (22–30 wks) with DCC compared to ICC. DCC also improves the cardiac output and the arterial blood pressure by 17% in term (36–40 wks), by 18% in moderately preterm (32–36 wks), by 21% in very preterm (28–32 wks) and by 24% in extremely preterm (20–28 wks) births compared to the ICC. A decline in oxygen saturation is observed in ICC received infants by 20% compared to the DCC received ones. At 30 weeks GA, SI were calculated for healthy newborns (1.18), and newborns with GR (1.38), PDA (1.22) and RDS (1.2) templates. Our results suggest that DCC provides superior hemodynamics and respiration at birth compared to ICC. This information will help preventing the complications associated with poor oxygenation arising in premature births and pre-screening the more critical babies in terms of their cardiovascular severity." @default.
• W2945598921 created "2019-05-29" @default.
• W2945598921 creator A5009304872 @default.
• W2945598921 creator A5013129400 @default.
• W2945598921 creator A5032542397 @default.
• W2945598921 creator A5069434422 @default.
• W2945598921 creator A5080723046 @default.
• W2945598921 date "2019-04-12" @default.
• W2945598921 modified "2023-10-17" @default.
• W2945598921 title "Transitional fetal hemodynamics and gas exchange in premature postpartum adaptation: immediate vs. delayed cord clamping" @default.
• W2945598921 cites W1571558322 @default.
• W2945598921 cites W1895883341 @default.
• W2945598921 cites W1960319812 @default.
• W2945598921 cites W1970848551 @default.
• W2945598921 cites W1976039178 @default.
• W2945598921 cites W1976431836 @default.
• W2945598921 cites W1979490938 @default.
• W2945598921 cites W1980413936 @default.
• W2945598921 cites W1980686214 @default.
• W2945598921 cites W1986569614 @default.
• W2945598921 cites W1992333717 @default.
• W2945598921 cites W2000237070 @default.
• W2945598921 cites W2007304725 @default.
• W2945598921 cites W2008620680 @default.
• W2945598921 cites W2014044464 @default.
• W2945598921 cites W2016050741 @default.
• W2945598921 cites W2017055786 @default.
• W2945598921 cites W2021427246 @default.
• W2945598921 cites W2027624791 @default.
• W2945598921 cites W2030864522 @default.
• W2945598921 cites W2041059291 @default.
• W2945598921 cites W2045024498 @default.
• W2945598921 cites W2062529882 @default.
• W2945598921 cites W2071094650 @default.
• W2945598921 cites W2071861594 @default.
• W2945598921 cites W2095462750 @default.
• W2945598921 cites W2099294561 @default.
• W2945598921 cites W2104076287 @default.
• W2945598921 cites W2109146591 @default.
• W2945598921 cites W2113741217 @default.
• W2945598921 cites W2114126052 @default.
• W2945598921 cites W2116695682 @default.
• W2945598921 cites W2138177728 @default.
• W2945598921 cites W2143334508 @default.
• W2945598921 cites W2146072187 @default.
• W2945598921 cites W2150959824 @default.
• W2945598921 cites W2156366255 @default.
• W2945598921 cites W2199185488 @default.
• W2945598921 cites W2213599575 @default.
• W2945598921 cites W2273311508 @default.
• W2945598921 cites W2330638273 @default.
• W2945598921 cites W2461945590 @default.
• W2945598921 cites W2483742247 @default.
• W2945598921 cites W2556862721 @default.
• W2945598921 cites W2750742399 @default.
• W2945598921 cites W2766541612 @default.
• W2945598921 cites W2964383204 @default.
• W2945598921 cites W4233859239 @default.
• W2945598921 cites W4252934329 @default.
• W2945598921 cites W4376596302 @default.
• W2945598921 doi "https://doi.org/10.1186/s40748-019-0100-1" @default.
• W2945598921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6460527" @default.
• W2945598921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31011431" @default.
• W2945598921 hasPublicationYear "2019" @default.
• W2945598921 type Work @default.
• W2945598921 sameAs 2945598921 @default.
• W2945598921 citedByCount "8" @default.
• W2945598921 countsByYear W29455989212022 @default.
• W2945598921 countsByYear W29455989212023 @default.
• W2945598921 crossrefType "journal-article" @default.
• W2945598921 hasAuthorship W2945598921A5009304872 @default.
• W2945598921 hasAuthorship W2945598921A5013129400 @default.
• W2945598921 hasAuthorship W2945598921A5032542397 @default.
• W2945598921 hasAuthorship W2945598921A5069434422 @default.
• W2945598921 hasAuthorship W2945598921A5080723046 @default.
• W2945598921 hasBestOaLocation W29455989211 @default.
• W2945598921 hasConcept C126322002 @default.
• W2945598921 hasConcept C164705383 @default.
• W2945598921 hasConcept C172680121 @default.
• W2945598921 hasConcept C178853913 @default.
• W2945598921 hasConcept C2778376644 @default.
• W2945598921 hasConcept C2779234561 @default.
• W2945598921 hasConcept C2781236024 @default.
• W2945598921 hasConcept C42219234 @default.
• W2945598921 hasConcept C54355233 @default.
• W2945598921 hasConcept C70289976 @default.
• W2945598921 hasConcept C71924100 @default.
• W2945598921 hasConcept C84393581 @default.
• W2945598921 hasConcept C86803240 @default.
• W2945598921 hasConceptScore W2945598921C126322002 @default.
• W2945598921 hasConceptScore W2945598921C164705383 @default.
• W2945598921 hasConceptScore W2945598921C172680121 @default.
• W2945598921 hasConceptScore W2945598921C178853913 @default.
• W2945598921 hasConceptScore W2945598921C2778376644 @default.
• W2945598921 hasConceptScore W2945598921C2779234561 @default.
• W2945598921 hasConceptScore W2945598921C2781236024 @default.
• W2945598921 hasConceptScore W2945598921C42219234 @default.
• W2945598921 hasConceptScore W2945598921C54355233 @default.
• W2945598921 hasConceptScore W2945598921C70289976 @default.
• W2945598921 hasConceptScore W2945598921C71924100 @default.

• next