FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945608545> ?p ?o ?g. }

• W2945608545 abstract "Vancomycin is commonly used to treat Enterococcus faecium (E. faecium) bacteremia. However, there are very few studies on the association between the trough concentration, area under the curve from 0 to 24 h /minimum inhibitory concentration (AUC24/MIC) ratio, and the therapeutic effect of vancomycin on E. faecium bacteremia. This study aimed to investigate the associations between vancomycin pharmacokinetic/pharmacodynamic parameters, patient characteristics, and mortality in patients with E. faecium bacteremia. This retrospective study included patients with E. faecium bacteremia who received vancomycin between April 2012 and February 2018 at a single acute care hospital in Japan. Patients who received renal replacement therapy (hemodialysis or continuous hemodiafiltration), had an unmeasured serum vancomycin concentration, with unmeasured laboratory values, or received other antibiotics for treating E. faecium bacteremia were excluded from the study. The bivariate associations between 30-day all-cause mortality and patient characteristics were assessed. Among 87 patients diagnosed with E. faecium bacteremia, 45 were included in the final analysis. Of these, 12 (26.7%) died within 30 days of the diagnosis. The vancomycin trough concentration was higher in the 30-day all-cause mortality patients than in the survival patients (20.5 vs. 14.6 μg/mL; P = 0.022). There was no significant difference in the proportion of patients with a vancomycin AUC24/MIC ≤389 between the groups. The 30-day all-cause mortality patients showed a higher Charlson Comorbidity Index (CCI) and Sequential Organ Failure Assessment score at the first measurement of the vancomycin trough concentration than the survival patients. The same finding was observed among patients with a high CCI score (≥5 points). Whereas the vancomycin trough concentration and AUC24/MIC ratio were not associated with mortality in patients with E. faecium bacteremia, disease severity was associated with mortality in these patients." @default.
• W2945608545 created "2019-05-29" @default.
• W2945608545 creator A5013856398 @default.
• W2945608545 creator A5047786920 @default.
• W2945608545 creator A5070255595 @default.
• W2945608545 creator A5073105756 @default.
• W2945608545 creator A5080965722 @default.
• W2945608545 date "2019-05-16" @default.
• W2945608545 modified "2023-10-16" @default.
• W2945608545 title "Association between vancomycin pharmacokinetic/pharmacodynamic parameters, patient characteristics, and mortality in patients with bacteremia caused by vancomycin-susceptible Enterococcus faecium: a single-center retrospective study" @default.
• W2945608545 cites W1550111394 @default.
• W2945608545 cites W1876587398 @default.
• W2945608545 cites W1898928487 @default.
• W2945608545 cites W1969756015 @default.
• W2945608545 cites W1998814468 @default.
• W2945608545 cites W1999105315 @default.
• W2945608545 cites W2026274122 @default.
• W2945608545 cites W2026584619 @default.
• W2945608545 cites W2043379193 @default.
• W2945608545 cites W2106444474 @default.
• W2945608545 cites W2113030904 @default.
• W2945608545 cites W2118378514 @default.
• W2945608545 cites W2121656227 @default.
• W2945608545 cites W2133120422 @default.
• W2945608545 cites W2150324881 @default.
• W2945608545 cites W2163750088 @default.
• W2945608545 cites W2733407954 @default.
• W2945608545 cites W2776379190 @default.
• W2945608545 cites W4211003757 @default.
• W2945608545 doi "https://doi.org/10.1186/s40780-019-0138-2" @default.
• W2945608545 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6485087" @default.
• W2945608545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31093330" @default.
• W2945608545 hasPublicationYear "2019" @default.
• W2945608545 type Work @default.
• W2945608545 sameAs 2945608545 @default.
• W2945608545 citedByCount "12" @default.
• W2945608545 countsByYear W29456085452020 @default.
• W2945608545 countsByYear W29456085452021 @default.
• W2945608545 countsByYear W29456085452022 @default.
• W2945608545 countsByYear W29456085452023 @default.
• W2945608545 crossrefType "journal-article" @default.
• W2945608545 hasAuthorship W2945608545A5013856398 @default.
• W2945608545 hasAuthorship W2945608545A5047786920 @default.
• W2945608545 hasAuthorship W2945608545A5070255595 @default.
• W2945608545 hasAuthorship W2945608545A5073105756 @default.
• W2945608545 hasAuthorship W2945608545A5080965722 @default.
• W2945608545 hasBestOaLocation W29456085451 @default.
• W2945608545 hasConcept C111113717 @default.
• W2945608545 hasConcept C112705442 @default.
• W2945608545 hasConcept C126322002 @default.
• W2945608545 hasConcept C141071460 @default.
• W2945608545 hasConcept C167135981 @default.
• W2945608545 hasConcept C2777677444 @default.
• W2945608545 hasConcept C2778063415 @default.
• W2945608545 hasConcept C2778980435 @default.
• W2945608545 hasConcept C2779443120 @default.
• W2945608545 hasConcept C2779489039 @default.
• W2945608545 hasConcept C2780272996 @default.
• W2945608545 hasConcept C501593827 @default.
• W2945608545 hasConcept C523546767 @default.
• W2945608545 hasConcept C54355233 @default.
• W2945608545 hasConcept C71924100 @default.
• W2945608545 hasConcept C86803240 @default.
• W2945608545 hasConcept C89423630 @default.
• W2945608545 hasConceptScore W2945608545C111113717 @default.
• W2945608545 hasConceptScore W2945608545C112705442 @default.
• W2945608545 hasConceptScore W2945608545C126322002 @default.
• W2945608545 hasConceptScore W2945608545C141071460 @default.
• W2945608545 hasConceptScore W2945608545C167135981 @default.
• W2945608545 hasConceptScore W2945608545C2777677444 @default.
• W2945608545 hasConceptScore W2945608545C2778063415 @default.
• W2945608545 hasConceptScore W2945608545C2778980435 @default.
• W2945608545 hasConceptScore W2945608545C2779443120 @default.
• W2945608545 hasConceptScore W2945608545C2779489039 @default.
• W2945608545 hasConceptScore W2945608545C2780272996 @default.
• W2945608545 hasConceptScore W2945608545C501593827 @default.
• W2945608545 hasConceptScore W2945608545C523546767 @default.
• W2945608545 hasConceptScore W2945608545C54355233 @default.
• W2945608545 hasConceptScore W2945608545C71924100 @default.
• W2945608545 hasConceptScore W2945608545C86803240 @default.
• W2945608545 hasConceptScore W2945608545C89423630 @default.
• W2945608545 hasIssue "1" @default.
• W2945608545 hasLocation W29456085451 @default.
• W2945608545 hasLocation W29456085452 @default.
• W2945608545 hasLocation W29456085453 @default.
• W2945608545 hasLocation W29456085454 @default.
• W2945608545 hasOpenAccess W2945608545 @default.
• W2945608545 hasPrimaryLocation W29456085451 @default.
• W2945608545 hasRelatedWork W1989106570 @default.
• W2945608545 hasRelatedWork W2131154741 @default.
• W2945608545 hasRelatedWork W2170787604 @default.
• W2945608545 hasRelatedWork W2378907788 @default.
• W2945608545 hasRelatedWork W2749128097 @default.
• W2945608545 hasRelatedWork W2801352875 @default.
• W2945608545 hasRelatedWork W3109215523 @default.
• W2945608545 hasRelatedWork W3168518059 @default.
• W2945608545 hasRelatedWork W3195778608 @default.
• W2945608545 hasRelatedWork W4367175696 @default.
• W2945608545 hasVolume "5" @default.
• W2945608545 isParatext "false" @default.

• next