FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945638839> ?p ?o ?g. }

• W2945638839 endingPage "396" @default.
• W2945638839 startingPage "389" @default.
• W2945638839 abstract "Background MR‐based metrics, including hepatobiliary phase (HBP) hypointense nodules without arterial phase hyperenhancement (APHE), and liver stiffness as measured by MR elastography are useful markers to stratify the risk of hepatocellular carcinoma (HCC) development in chronic liver disease patients. However, prospective studies are needed to clarify their utility. Purpose To perform a risk analysis of HCC development in chronic liver disease patients, with a focus on MR‐based biomarkers. Study Type Prospective. Subjects Consecutive 110 cirrhotic patients (61 males, 49 females) without a history of HCC who matched the inclusion criteria. Field Strength/Sequence 3T/3D gradient‐echo T 1 ‐weighted images and MR elastography. Assessment Patients underwent MRI for HCC screening and attended follow‐up appointments every 3 months. The primary endpoint was the development of hypervascular HCC. Patients were classified according to the presence of an HBP hypointense nodule without APHE (if present in the liver, the patient was classified in nonclean liver group; if absent, clean liver group), and stiffness value on MR elastography (soft liver, <4.0 kPa; stiff liver, ≥4.0 kPa) at the initial examination. Statistical Tests Risk factors were identified in univariate and multivariate Cox regression models. Incidence rates of HCC development were evaluated using the Kaplan–Meier method. Results Patients were classified into clean‐liver ( n = 76) and nonclean‐liver groups ( n = 34), and into soft‐liver ( n = 53) and stiff‐liver groups ( n = 45). During the follow‐up period (median, 21.0 months), 16 patients developed hypervascular HCC. Patients in the nonclean‐liver group showed a higher incidence of hypervascular HCC than those in the clean‐liver group (3‐year HCC incidence rates: 50.4% and 5.7%, respectively; P < 0.05). A nonclean liver was independently associated with hypervascular HCC development (hazard ratio, 18.75; 95% confidence interval, 4.83–128.63; P < 0.0001), but stiff liver was not (1.91; 0.66–6.23; P = 0.23). Data Conclusion An HBP hypointense nodule without APHE observed on a gadoxetic acid‐enhanced MR image is a strong indicator of subsequent development of hypervascular HCC in patients with chronic liver disease. Level of Evidence: 2 Technical Efficacy Stage: 5 J. Magn. Reson. Imaging 2020;51:389–396." @default.
• W2945638839 created "2019-05-29" @default.
• W2945638839 creator A5003573363 @default.
• W2945638839 creator A5008248425 @default.
• W2945638839 creator A5034439906 @default.
• W2945638839 creator A5037423839 @default.
• W2945638839 creator A5058386183 @default.
• W2945638839 creator A5073985175 @default.
• W2945638839 creator A5081837886 @default.
• W2945638839 date "2019-05-23" @default.
• W2945638839 modified "2023-10-02" @default.
• W2945638839 title "MRI‐based risk factors of hepatocellular carcinoma in patients with chronic liver disease: A prospective observational study" @default.
• W2945638839 cites W1140174741 @default.
• W2945638839 cites W1759343396 @default.
• W2945638839 cites W1811796431 @default.
• W2945638839 cites W1903242843 @default.
• W2945638839 cites W1968132399 @default.
• W2945638839 cites W1977485345 @default.
• W2945638839 cites W1987509611 @default.
• W2945638839 cites W1996202257 @default.
• W2945638839 cites W2001599286 @default.
• W2945638839 cites W2009762194 @default.
• W2945638839 cites W2014107696 @default.
• W2945638839 cites W2017208188 @default.
• W2945638839 cites W2024006175 @default.
• W2945638839 cites W2027498662 @default.
• W2945638839 cites W2053262689 @default.
• W2945638839 cites W2074343504 @default.
• W2945638839 cites W2082755477 @default.
• W2945638839 cites W2086719465 @default.
• W2945638839 cites W2088652574 @default.
• W2945638839 cites W2117827638 @default.
• W2945638839 cites W2123992522 @default.
• W2945638839 cites W2126017889 @default.
• W2945638839 cites W2132894770 @default.
• W2945638839 cites W2133024534 @default.
• W2945638839 cites W2155625547 @default.
• W2945638839 cites W2163656263 @default.
• W2945638839 cites W2167835267 @default.
• W2945638839 cites W2525980773 @default.
• W2945638839 cites W2776771121 @default.
• W2945638839 cites W2796067155 @default.
• W2945638839 cites W2796885144 @default.
• W2945638839 cites W2883522758 @default.
• W2945638839 cites W2898017113 @default.
• W2945638839 doi "https://doi.org/10.1002/jmri.26797" @default.
• W2945638839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31120640" @default.
• W2945638839 hasPublicationYear "2019" @default.
• W2945638839 type Work @default.
• W2945638839 sameAs 2945638839 @default.
• W2945638839 citedByCount "8" @default.
• W2945638839 countsByYear W29456388392021 @default.
• W2945638839 countsByYear W29456388392022 @default.
• W2945638839 countsByYear W29456388392023 @default.
• W2945638839 crossrefType "journal-article" @default.
• W2945638839 hasAuthorship W2945638839A5003573363 @default.
• W2945638839 hasAuthorship W2945638839A5008248425 @default.
• W2945638839 hasAuthorship W2945638839A5034439906 @default.
• W2945638839 hasAuthorship W2945638839A5037423839 @default.
• W2945638839 hasAuthorship W2945638839A5058386183 @default.
• W2945638839 hasAuthorship W2945638839A5073985175 @default.
• W2945638839 hasAuthorship W2945638839A5081837886 @default.
• W2945638839 hasConcept C126322002 @default.
• W2945638839 hasConcept C126838900 @default.
• W2945638839 hasConcept C143753070 @default.
• W2945638839 hasConcept C144301174 @default.
• W2945638839 hasConcept C188816634 @default.
• W2945638839 hasConcept C2776231280 @default.
• W2945638839 hasConcept C2777075537 @default.
• W2945638839 hasConcept C2777214474 @default.
• W2945638839 hasConcept C2777690781 @default.
• W2945638839 hasConcept C2778019345 @default.
• W2945638839 hasConcept C2779102576 @default.
• W2945638839 hasConcept C2780826214 @default.
• W2945638839 hasConcept C2994217296 @default.
• W2945638839 hasConcept C38180746 @default.
• W2945638839 hasConcept C50382708 @default.
• W2945638839 hasConcept C71924100 @default.
• W2945638839 hasConcept C90924648 @default.
• W2945638839 hasConceptScore W2945638839C126322002 @default.
• W2945638839 hasConceptScore W2945638839C126838900 @default.
• W2945638839 hasConceptScore W2945638839C143753070 @default.
• W2945638839 hasConceptScore W2945638839C144301174 @default.
• W2945638839 hasConceptScore W2945638839C188816634 @default.
• W2945638839 hasConceptScore W2945638839C2776231280 @default.
• W2945638839 hasConceptScore W2945638839C2777075537 @default.
• W2945638839 hasConceptScore W2945638839C2777214474 @default.
• W2945638839 hasConceptScore W2945638839C2777690781 @default.
• W2945638839 hasConceptScore W2945638839C2778019345 @default.
• W2945638839 hasConceptScore W2945638839C2779102576 @default.
• W2945638839 hasConceptScore W2945638839C2780826214 @default.
• W2945638839 hasConceptScore W2945638839C2994217296 @default.
• W2945638839 hasConceptScore W2945638839C38180746 @default.
• W2945638839 hasConceptScore W2945638839C50382708 @default.
• W2945638839 hasConceptScore W2945638839C71924100 @default.
• W2945638839 hasConceptScore W2945638839C90924648 @default.
• W2945638839 hasIssue "2" @default.
• W2945638839 hasLocation W29456388391 @default.

• next