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- W2945654002 abstract "This study sought to investigate the antimicrobial activity of sixBackground: plants used in traditional medicine in Africa. The antimicrobial activity of the six medicinal plant extracts (aqueousMethods: and ethanol) were evaluated against (ATCC 21784), Proteus mirabilis (ATCC27856) were using thePseudomonas aeruginosa Aspergillus fumigatus agar-well diffusion protocol. The activities of these extracts were compared with the positive controls chloramphenicol and griseofulvin. Similarly, the phytochemicals from the extracts were qualitatively assayed and their percentage yield calculated by standard methods. The bacterial organisms used, and , wereResults: P. mirabilis P. aeruginosa slightly-to-highly susceptible to aqueous and ethanolic extracts from the various test plants, while was insensitive to the treatments. The ethanolic A. fumigatus extracts of the sampled plants showed superior inhibitory performance on the target bacteria to the aqueous extracts. Aqueous and ethanolic extracts of , and showed inhibitoryAframomum melegueta Moringa oleifera Cola nitida consistency against the target bacteria. Superior inhibitory activity was observed for ethanol extracts of seed and pod against A. melegueta M. oleifera and . Variations in phytochemicals were noticedP. mirabilis P. aeruginosa across solvents and plant parts for all plants. Phenols were detected in the aqueous and ethanolic extracts of and , but relatively C. nitida Cola acuminate appeared denser in extracts of seed and A. melegueta Chrysophyllum albidium fruits. The extracts of , and tested positive C. nitida C. acuminate A. melegueta for the presence of flavonoids, which were undetected in and C. albidium M. seed and pod extracts. None of the extracts showed the presence ofoleifera every phytochemical assayed during the study. Extracts of the medicinal plants assessed in this study showedConclusions: antibacterial potential. Developing new methodologies that preserve the bioactive potency of phyto-extracts for optimal microbicidal activity is promising for development of safe, non-reactive pharmaceuticals" @default.
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- W2945654002 date "2019-01-21" @default.
- W2945654002 modified "2023-09-27" @default.
- W2945654002 title "Comparative study of the phytochemicals and in vitro antimicrobial potential of six medicinal plants" @default.
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