FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945692803> ?p ?o ?g. }

• W2945692803 endingPage "67" @default.
• W2945692803 startingPage "58" @default.
• W2945692803 abstract "Prediction of complications after pancreatoduodenectomy (PD) remains of interest. Blood parameters and biomarkers during first and second postoperative days (POD1, POD2) may be early indicators of complications. This case-control study included 50 patients. Baseline, POD1 and POD2 values of leukocytes, neutrophils, lymphocytes, platelets, hemoglobin, C-reactive protein (CRP), procalcitonin and arterial lactate were compared between individuals presenting Clavien ≥ III morbidity, pancreatic fistula (PF) or clinically relevant PF (CRPF) and those without these morbidities. Common variables reaching significance were further analyzed in order to calculate a predictive score. Severe morbidity, PF and CRPF rates were 28.0%, 26.0% and 14.0%, respectively. Patients with severe morbidity had lower leukocytes on POD2 (P = 0.04). Patients with PF presented higher CRP on POD2 (P = 0.001), higher lactate on POD1 (P = 0.007) and POD2 (P = 0.008), and lower lymphocytes on POD1 (P = 0.007) and POD2 (P = 0.008). Patients with CRPF had lower leukocytes and neutrophils on POD1 (P = 0.048, P = 0.038), lower lymphocytes on POD1 (P = 0.001) and POD2 (P = 0.003), and higher CRP on POD2 (P = 0.001). Baseline parameters and procalcitonin obtained no statistical associations. Score was defined according to lymphocytes on POD1 < 650/µL and CRP on POD2 ≥ 250 mg/L allocating patients in 3 risk categories. PF and CRPF rates were statistically higher as risk category increased (P<0.001). Receiver operating characteristic curves and Hosmer–Lemeshow tests showed a good accuracy. Impaired immunological reaction during early postoperative period (lower leukocytes and, particularly, lymphocytes) in response to surgical aggression would favor complications after PD. Likewise, acidosis (higher arterial lactate) could behave as risk factor of PF. An elevated CRP on POD2 is also an early biomarker of PF. Our novel score based on postoperative lymphocyte count and CRP seems reliable for early prediction of PF." @default.
• W2945692803 created "2019-05-29" @default.
• W2945692803 creator A5012187791 @default.
• W2945692803 creator A5043067305 @default.
• W2945692803 creator A5047071305 @default.
• W2945692803 creator A5047664851 @default.
• W2945692803 creator A5053198912 @default.
• W2945692803 creator A5081981713 @default.
• W2945692803 date "2020-02-01" @default.
• W2945692803 modified "2023-10-17" @default.
• W2945692803 title "Impaired immune reaction and increased lactate and C-reactive protein for early prediction of severe morbidity and pancreatic fistula after pancreatoduodenectomy" @default.
• W2945692803 cites W1557016905 @default.
• W2945692803 cites W1797832744 @default.
• W2945692803 cites W2014582424 @default.
• W2945692803 cites W2023632745 @default.
• W2945692803 cites W2079026146 @default.
• W2945692803 cites W2085293124 @default.
• W2945692803 cites W2089043590 @default.
• W2945692803 cites W2096998881 @default.
• W2945692803 cites W2112332605 @default.
• W2945692803 cites W2117853299 @default.
• W2945692803 cites W2179176421 @default.
• W2945692803 cites W2286910017 @default.
• W2945692803 cites W2394686297 @default.
• W2945692803 cites W2397718225 @default.
• W2945692803 cites W2399960089 @default.
• W2945692803 cites W2407617349 @default.
• W2945692803 cites W2410563287 @default.
• W2945692803 cites W2510317042 @default.
• W2945692803 cites W2522210459 @default.
• W2945692803 cites W2565595087 @default.
• W2945692803 cites W2588671547 @default.
• W2945692803 cites W2604303217 @default.
• W2945692803 cites W2605854216 @default.
• W2945692803 cites W2754929199 @default.
• W2945692803 cites W2774066444 @default.
• W2945692803 cites W2787446092 @default.
• W2945692803 cites W2791280104 @default.
• W2945692803 cites W915161420 @default.
• W2945692803 doi "https://doi.org/10.1016/j.hbpd.2019.05.003" @default.
• W2945692803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31153788" @default.
• W2945692803 hasPublicationYear "2020" @default.
• W2945692803 type Work @default.
• W2945692803 sameAs 2945692803 @default.
• W2945692803 citedByCount "5" @default.
• W2945692803 countsByYear W29456928032021 @default.
• W2945692803 countsByYear W29456928032022 @default.
• W2945692803 countsByYear W29456928032023 @default.
• W2945692803 crossrefType "journal-article" @default.
• W2945692803 hasAuthorship W2945692803A5012187791 @default.
• W2945692803 hasAuthorship W2945692803A5043067305 @default.
• W2945692803 hasAuthorship W2945692803A5047071305 @default.
• W2945692803 hasAuthorship W2945692803A5047664851 @default.
• W2945692803 hasAuthorship W2945692803A5053198912 @default.
• W2945692803 hasAuthorship W2945692803A5081981713 @default.
• W2945692803 hasConcept C10936531 @default.
• W2945692803 hasConcept C126322002 @default.
• W2945692803 hasConcept C2776914184 @default.
• W2945692803 hasConcept C2778384902 @default.
• W2945692803 hasConcept C2781195455 @default.
• W2945692803 hasConcept C58471807 @default.
• W2945692803 hasConcept C71924100 @default.
• W2945692803 hasConcept C90924648 @default.
• W2945692803 hasConceptScore W2945692803C10936531 @default.
• W2945692803 hasConceptScore W2945692803C126322002 @default.
• W2945692803 hasConceptScore W2945692803C2776914184 @default.
• W2945692803 hasConceptScore W2945692803C2778384902 @default.
• W2945692803 hasConceptScore W2945692803C2781195455 @default.
• W2945692803 hasConceptScore W2945692803C58471807 @default.
• W2945692803 hasConceptScore W2945692803C71924100 @default.
• W2945692803 hasConceptScore W2945692803C90924648 @default.
• W2945692803 hasIssue "1" @default.
• W2945692803 hasLocation W29456928031 @default.
• W2945692803 hasOpenAccess W2945692803 @default.
• W2945692803 hasPrimaryLocation W29456928031 @default.
• W2945692803 hasRelatedWork W1848260229 @default.
• W2945692803 hasRelatedWork W1980636593 @default.
• W2945692803 hasRelatedWork W2266663782 @default.
• W2945692803 hasRelatedWork W2350453960 @default.
• W2945692803 hasRelatedWork W2364362829 @default.
• W2945692803 hasRelatedWork W2601062120 @default.
• W2945692803 hasRelatedWork W2614904911 @default.
• W2945692803 hasRelatedWork W3030123588 @default.
• W2945692803 hasRelatedWork W4361289300 @default.
• W2945692803 hasRelatedWork W4385347625 @default.
• W2945692803 hasVolume "19" @default.
• W2945692803 isParatext "false" @default.
• W2945692803 isRetracted "false" @default.
• W2945692803 magId "2945692803" @default.
• W2945692803 workType "article" @default.