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• W2945710230 abstract "Leukotoxin (LtxA) (trade name, Leukothera) is a protein secreted by the oral bacterium Aggregatibacter actinomycetemcomitans . A. actinomycetemcomitans is an oral pathogen strongly associated with development of localized aggressive periodontitis. LtxA acts as a virulence factor for A. actinomycetemcomitans by binding to the β 2 integrin lymphocyte function-associated antigen-1 (LFA-1; CD11a/CD18) on white blood cells (WBCs) and causing cell death." @default.
• W2945710230 created "2019-05-29" @default.
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• W2945710230 date "2019-08-01" @default.
• W2945710230 modified "2023-10-14" @default.
• W2945710230 title "Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA) Requires Death Receptor Fas, in Addition to LFA-1, To Trigger Cell Death in T Lymphocytes" @default.
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• W2945710230 doi "https://doi.org/10.1128/iai.00309-19" @default.
• W2945710230 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6652782" @default.
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