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• W2945751843 abstract "Abstract The gastrointestinal microbiota plays a critical role on host health and metabolism. This is particularly important in teleost nutrition, because fish do not possess some of the necessary enzymes to cope with the dietary challenges of aquaculture production. A main difficulty within fish nutrition is its dependence on fish meal, an unsustainable commodity and a source of organic pollutants. The most obvious sustainable alternatives to fish meal are plant feedstuffs, but their nutritive value is limited by the presence of high levels of non-starch polysaccharides (NSP), which are not metabolized by fish. The composition of fish-gut microbial communities have been demonstrated to adapt when the host is fed different ingredients. Thus, we hypothesized that a selective pressure of plant-based diets on fish gut microbiota, could be a beneficial strategy for an enrichment of bacteria with a secretome able to mobilize dietary NSP. By targeting bacterial sporulating isolates with diverse carbohydrase activities from the gut of European sea bass, we have obtained isolates with high probiotic potential. By inferring the adaptive fitness to the fish gut and the amenability to industrial processing, we identified the best two candidates to become industrially valuable probiotics. This potential was confirmed in vivo , since one of the select isolates lead to a better growth and feed utilization efficiency in fish fed probiotic-supplemented plant-based diets, thus contributing for sustainable and more cost-effective aquaculture practices." @default.
• W2945751843 created "2019-05-29" @default.
• W2945751843 creator A5010391603 @default.
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• W2945751843 date "2019-04-23" @default.
• W2945751843 modified "2023-10-18" @default.
• W2945751843 title "Selection of carbohydrate-active probiotics from the gut of carnivorous fish fed plant-based diets" @default.
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• W2945751843 doi "https://doi.org/10.1038/s41598-019-42716-7" @default.
• W2945751843 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6476879" @default.
• W2945751843 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31011158" @default.
• W2945751843 hasPublicationYear "2019" @default.
• W2945751843 type Work @default.
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