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• W2945784502 abstract "Over the last decade, developments in single molecule imaging have changed our vision of synaptic physiology. By providing high spatio-temporal resolution maps of the molecular actors of neurotransmissions, these techniques have revealed that pre- and post-synaptic proteins are not randomly distributed but precisely organized at the nanoscale, and that this specific organization is dynamically regulated. At the centre of synaptic transmissions, neurotransmitter receptors have been shown to form nanodomains at synapses and to dynamically move in and out of these confinement areas through lateral diffusion within the membrane plane on millisecond timescales, thereby directly contributing to the regulation of synaptic transmission and plasticity. Since the vast majority of these discoveries originated from observations made on dissociated neurons lacking several features of brain tissue (e.g. three-dimensional organization, tissue density), they were initially considered with caution. However, the recent implementation of single-particle tracking (SPT) approaches in cultured and acute brain preparations confirmed that early findings on the dynamic properties of receptors at the surface of neurons can be extended to more physiological conditions. Taking example of dopamine D1 and NMDA glutamate receptors we here review our current knowledge of the features of neurotransmitter receptor surface diffusion in intact brain tissue. Through detailed comparison with cultured neurons, we also discuss how these biophysical properties are influenced by the complexity of the extracellular environment. This article is part of the special issue entitled ‘Mobility and trafficking of neuronal membrane proteins’." @default.
• W2945784502 created "2019-05-29" @default.
• W2945784502 creator A5040998161 @default.
• W2945784502 creator A5072499125 @default.
• W2945784502 date "2020-06-01" @default.
• W2945784502 modified "2023-10-16" @default.
• W2945784502 title "Surface trafficking of neurotransmitter receptors: From cultured neurons to intact brain preparations" @default.
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• W2945784502 cites W1868150518 @default.
• W2945784502 cites W1965202553 @default.
• W2945784502 cites W1966298771 @default.
• W2945784502 cites W1970607961 @default.
• W2945784502 cites W1971067804 @default.
• W2945784502 cites W1971505763 @default.
• W2945784502 cites W1978458868 @default.
• W2945784502 cites W1980059018 @default.
• W2945784502 cites W1982726026 @default.
• W2945784502 cites W1984367406 @default.
• W2945784502 cites W1987878093 @default.
• W2945784502 cites W1989946888 @default.
• W2945784502 cites W1992004763 @default.
• W2945784502 cites W1992746109 @default.
• W2945784502 cites W1994778254 @default.
• W2945784502 cites W1995949213 @default.
• W2945784502 cites W1999860614 @default.
• W2945784502 cites W2000779549 @default.
• W2945784502 cites W2001105299 @default.
• W2945784502 cites W2002469804 @default.
• W2945784502 cites W2014713864 @default.
• W2945784502 cites W2016166286 @default.
• W2945784502 cites W2017934591 @default.
• W2945784502 cites W2021512296 @default.
• W2945784502 cites W2030976437 @default.
• W2945784502 cites W2032706441 @default.
• W2945784502 cites W2032730889 @default.
• W2945784502 cites W2036796078 @default.
• W2945784502 cites W2042795119 @default.
• W2945784502 cites W2051507702 @default.
• W2945784502 cites W2051576463 @default.
• W2945784502 cites W2054455698 @default.
• W2945784502 cites W2058113433 @default.
• W2945784502 cites W2059480421 @default.
• W2945784502 cites W2060931853 @default.
• W2945784502 cites W2063227156 @default.
• W2945784502 cites W2065460329 @default.
• W2945784502 cites W2069382449 @default.
• W2945784502 cites W2072543390 @default.
• W2945784502 cites W2073514734 @default.
• W2945784502 cites W2080241882 @default.
• W2945784502 cites W2080550406 @default.
• W2945784502 cites W2081411933 @default.
• W2945784502 cites W2084807003 @default.
• W2945784502 cites W2084838390 @default.
• W2945784502 cites W2085955152 @default.
• W2945784502 cites W2087715700 @default.
• W2945784502 cites W2101151644 @default.
• W2945784502 cites W2101890054 @default.
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• W2945784502 cites W2128574573 @default.
• W2945784502 cites W2145400846 @default.
• W2945784502 cites W2151232434 @default.
• W2945784502 cites W2154321074 @default.
• W2945784502 cites W2155002338 @default.
• W2945784502 cites W2159477924 @default.
• W2945784502 cites W2161458381 @default.
• W2945784502 cites W2213567908 @default.
• W2945784502 cites W2223647828 @default.
• W2945784502 cites W2298172813 @default.
• W2945784502 cites W2338273833 @default.
• W2945784502 cites W2354407467 @default.
• W2945784502 cites W2410122486 @default.
• W2945784502 cites W2463951281 @default.
• W2945784502 cites W2505014287 @default.
• W2945784502 cites W2593745692 @default.
• W2945784502 cites W2624067177 @default.
• W2945784502 cites W2735674872 @default.
• W2945784502 cites W2745168257 @default.
• W2945784502 cites W2765658539 @default.
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• W2945784502 cites W2769047724 @default.
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• W2945784502 doi "https://doi.org/10.1016/j.neuropharm.2019.05.019" @default.
• W2945784502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31108111" @default.
• W2945784502 hasPublicationYear "2020" @default.
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