Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945797415> ?p ?o ?g. }
- W2945797415 endingPage "567" @default.
- W2945797415 startingPage "555" @default.
- W2945797415 abstract "Application of hydrogels can be an effective technique in transferring the adipose-derived stem cells (ASCs) to injured tissue and their protection from further complications. Besides, acellular dermal matrix (ADM) has successfully been used in treatment of wounds. In this study, a combination of hylauronic acid (HA) and ASCs (HA/ASCs) was applied on burn wounds and the injured area was then covered by an ADM dressing in a rat model (ADM-HA/ASCs). Wound healing was evaluated by histopathological, histomorphometrical, molecular, biochemical, and scanning electron microscopy assessments on days 7, 14, and 28 post-wounding. ADM-HA/ASCs stimulated healing significantly more than the ADM-HA and ADM treated wounds, as it led to reduced inflammation, and improved angiogenesis and enhanced granulation tissue formation. Expression of interleukin-1β (IL-1β) and transforming growth factor-β1 (TGF-β1) was lower in the ADM-HA/ASCs treated wounds than the ADM-HA and ADM groups, at the seventh post-wounding day. ADM-HA/ASCs also enhanced the expression level of TGF-β1 mRNA at 14 day post-wounding that was parallel to the experimental data from histological and biochemical assessments and confirmed the positive role of ASCs in repair of burn wounds. Additionally, increase in basic fibroblast growth factor (bFGF) expression and decreased TGF-β1 level on the 28th post-wounding day indicated the anti-scarring activity of ASCs. HA loaded by adipose stem cells can represent a promising strategy in accelerating burn wound healing." @default.
- W2945797415 created "2019-05-29" @default.
- W2945797415 creator A5027549257 @default.
- W2945797415 creator A5044390360 @default.
- W2945797415 creator A5081823744 @default.
- W2945797415 date "2019-05-13" @default.
- W2945797415 modified "2023-10-17" @default.
- W2945797415 title "Hyaluronic acid hydrogel loaded by adipose stem cells enhances wound healing by modulating IL‐1β, TGF‐β1, and bFGF in burn wound model in rat" @default.
- W2945797415 cites W1564967704 @default.
- W2945797415 cites W1588928817 @default.
- W2945797415 cites W1804576389 @default.
- W2945797415 cites W1964208207 @default.
- W2945797415 cites W1964723987 @default.
- W2945797415 cites W1972577039 @default.
- W2945797415 cites W1976712120 @default.
- W2945797415 cites W1977784832 @default.
- W2945797415 cites W1981667520 @default.
- W2945797415 cites W1982480837 @default.
- W2945797415 cites W1982773128 @default.
- W2945797415 cites W1988052127 @default.
- W2945797415 cites W1999267604 @default.
- W2945797415 cites W2001589153 @default.
- W2945797415 cites W2006315282 @default.
- W2945797415 cites W2007290442 @default.
- W2945797415 cites W2027216673 @default.
- W2945797415 cites W2027921872 @default.
- W2945797415 cites W2031663540 @default.
- W2945797415 cites W2033641981 @default.
- W2945797415 cites W2033672696 @default.
- W2945797415 cites W2037098160 @default.
- W2945797415 cites W2041983460 @default.
- W2945797415 cites W2045232408 @default.
- W2945797415 cites W2050733989 @default.
- W2945797415 cites W2053984526 @default.
- W2945797415 cites W2055569470 @default.
- W2945797415 cites W2055960439 @default.
- W2945797415 cites W2060167399 @default.
- W2945797415 cites W2061251554 @default.
- W2945797415 cites W2063514251 @default.
- W2945797415 cites W2065316185 @default.
- W2945797415 cites W2071062791 @default.
- W2945797415 cites W2077410924 @default.
- W2945797415 cites W2080044875 @default.
- W2945797415 cites W2080407630 @default.
- W2945797415 cites W2090223479 @default.
- W2945797415 cites W2092275496 @default.
- W2945797415 cites W2106035984 @default.
- W2945797415 cites W2108226844 @default.
- W2945797415 cites W2111179262 @default.
- W2945797415 cites W2116820472 @default.
- W2945797415 cites W2123735793 @default.
- W2945797415 cites W2124843142 @default.
- W2945797415 cites W2125364971 @default.
- W2945797415 cites W2140095796 @default.
- W2945797415 cites W2140686491 @default.
- W2945797415 cites W2141459104 @default.
- W2945797415 cites W2142272679 @default.
- W2945797415 cites W2155750048 @default.
- W2945797415 cites W2160818092 @default.
- W2945797415 cites W2161853479 @default.
- W2945797415 cites W2162648668 @default.
- W2945797415 cites W2166365091 @default.
- W2945797415 cites W2169430024 @default.
- W2945797415 cites W2170671424 @default.
- W2945797415 cites W2171311487 @default.
- W2945797415 cites W2176823143 @default.
- W2945797415 cites W2192610240 @default.
- W2945797415 cites W2226636383 @default.
- W2945797415 cites W2237190790 @default.
- W2945797415 cites W2253619901 @default.
- W2945797415 cites W2277369732 @default.
- W2945797415 cites W2286960988 @default.
- W2945797415 cites W2335117843 @default.
- W2945797415 cites W2348656062 @default.
- W2945797415 cites W2468880389 @default.
- W2945797415 cites W2514840159 @default.
- W2945797415 cites W2579494889 @default.
- W2945797415 cites W2599007678 @default.
- W2945797415 cites W2605271078 @default.
- W2945797415 cites W2607832788 @default.
- W2945797415 cites W2683627480 @default.
- W2945797415 cites W2724955547 @default.
- W2945797415 cites W2766411346 @default.
- W2945797415 cites W2792456918 @default.
- W2945797415 cites W2803917922 @default.
- W2945797415 cites W2807006685 @default.
- W2945797415 cites W2884260619 @default.
- W2945797415 doi "https://doi.org/10.1002/jbm.b.34411" @default.
- W2945797415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31081996" @default.
- W2945797415 hasPublicationYear "2019" @default.
- W2945797415 type Work @default.
- W2945797415 sameAs 2945797415 @default.
- W2945797415 citedByCount "34" @default.
- W2945797415 countsByYear W29457974152020 @default.
- W2945797415 countsByYear W29457974152021 @default.
- W2945797415 countsByYear W29457974152022 @default.
- W2945797415 countsByYear W29457974152023 @default.
- W2945797415 crossrefType "journal-article" @default.