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- W2945804322 abstract "Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular pattern recognition receptor (PRR) responsible for sensing bacterial peptidoglycan fragments. Stimulation of NOD1 leads to a robust innate immune response via activation of the major transcription factor NF-κB. In addition to peptidoglycan sensing, NOD1 and the closely related PRR NOD2 have been linked to inflammation by responding to the endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR)." @default.
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- W2945804322 date "2019-08-01" @default.
- W2945804322 modified "2023-09-27" @default.
- W2945804322 title "Activation of the Endoplasmic Reticulum Stress Response Impacts the NOD1 Signaling Pathway" @default.
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- W2945804322 doi "https://doi.org/10.1128/iai.00826-18" @default.
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