Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945851246> ?p ?o ?g. }
- W2945851246 endingPage "28" @default.
- W2945851246 startingPage "20" @default.
- W2945851246 abstract "The aim of this study was to observe the possible function of increased superoxide and NO production in the response of barley root tip to the harmful level of Cd. While superoxide generation was detected only in the transition zone, the formation of NO was observed in the apical elongation zones of the control root tips. However, the root region with the superoxide generation was also associated with peroxynitrite specific fluorescence signal. Superoxide, H2O2 and peroxynitrite generation increased with Cd treatment in a dose-dependent manner. In turn, NO level increased at low 10-20 μM but decreased at high 50-60 μM Cd concentrations in comparison with the control. While co-treatment of roots with rotenone markedly attenuated the Cd-induced superoxide generation and lipid peroxidation, it increased the level of NO in the root tips. Although rotenone did not influence the Cd-induced increase of GPX activity at 10-30 μM Cd concentrations, it markedly reversed the high 40-60 μM Cd concentrations-induced decline of GPX activity. Cd-induced cell death was associated with robust superoxide generation, but not with a high level of peroxynitrite. The Cd-evoked inhibition of root growth was significantly reversed by a strong antioxidant N-acetyl cysteine but not by a peroxynitrite scavenger uric acid, suggesting that similarly to Cd-induced cell death, an imbalance in the ROS homeostasis and not an enhanced level of peroxynitrite is responsible for the Cd-induced root growth inhibition. Based on these findings, it can be assumed that NO acts mainly in the regulation of superoxide level in the tips of root. Under Cd stress, the enhanced NO level is involved in the scavenging of highly toxic superoxide through the formation of peroxynitrite, thus reducing the superoxide-mediated cell death in barley root." @default.
- W2945851246 created "2019-05-29" @default.
- W2945851246 creator A5018679955 @default.
- W2945851246 creator A5020922986 @default.
- W2945851246 creator A5024341244 @default.
- W2945851246 creator A5045953137 @default.
- W2945851246 date "2019-07-01" @default.
- W2945851246 modified "2023-09-24" @default.
- W2945851246 title "Enhanced nitric oxide generation mitigates cadmium toxicity via superoxide scavenging leading to the formation of peroxynitrite in barley root tip" @default.
- W2945851246 cites W1824207682 @default.
- W2945851246 cites W1967729440 @default.
- W2945851246 cites W1977264698 @default.
- W2945851246 cites W1981692510 @default.
- W2945851246 cites W1989315201 @default.
- W2945851246 cites W1989800012 @default.
- W2945851246 cites W1995191054 @default.
- W2945851246 cites W1996553592 @default.
- W2945851246 cites W2006491538 @default.
- W2945851246 cites W2013179787 @default.
- W2945851246 cites W2014282903 @default.
- W2945851246 cites W2014677149 @default.
- W2945851246 cites W2016138645 @default.
- W2945851246 cites W2019512370 @default.
- W2945851246 cites W2028378300 @default.
- W2945851246 cites W2031920312 @default.
- W2945851246 cites W2042245748 @default.
- W2945851246 cites W2042821596 @default.
- W2945851246 cites W2052499827 @default.
- W2945851246 cites W2052916710 @default.
- W2945851246 cites W2053511457 @default.
- W2945851246 cites W2055569736 @default.
- W2945851246 cites W2058169080 @default.
- W2945851246 cites W2059633974 @default.
- W2945851246 cites W2060049759 @default.
- W2945851246 cites W2061232840 @default.
- W2945851246 cites W2077235164 @default.
- W2945851246 cites W2082384602 @default.
- W2945851246 cites W2090315534 @default.
- W2945851246 cites W2092721077 @default.
- W2945851246 cites W2099070633 @default.
- W2945851246 cites W2105101792 @default.
- W2945851246 cites W2111388491 @default.
- W2945851246 cites W2119164193 @default.
- W2945851246 cites W2136798531 @default.
- W2945851246 cites W2142663875 @default.
- W2945851246 cites W2146688919 @default.
- W2945851246 cites W2341914988 @default.
- W2945851246 cites W2505918697 @default.
- W2945851246 cites W2512547468 @default.
- W2945851246 cites W2535362621 @default.
- W2945851246 cites W4293247451 @default.
- W2945851246 doi "https://doi.org/10.1016/j.jplph.2019.05.003" @default.
- W2945851246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31125706" @default.
- W2945851246 hasPublicationYear "2019" @default.
- W2945851246 type Work @default.
- W2945851246 sameAs 2945851246 @default.
- W2945851246 citedByCount "12" @default.
- W2945851246 countsByYear W29458512462019 @default.
- W2945851246 countsByYear W29458512462020 @default.
- W2945851246 countsByYear W29458512462021 @default.
- W2945851246 countsByYear W29458512462022 @default.
- W2945851246 countsByYear W29458512462023 @default.
- W2945851246 crossrefType "journal-article" @default.
- W2945851246 hasAuthorship W2945851246A5018679955 @default.
- W2945851246 hasAuthorship W2945851246A5020922986 @default.
- W2945851246 hasAuthorship W2945851246A5024341244 @default.
- W2945851246 hasAuthorship W2945851246A5045953137 @default.
- W2945851246 hasConcept C12554922 @default.
- W2945851246 hasConcept C178790620 @default.
- W2945851246 hasConcept C181199279 @default.
- W2945851246 hasConcept C185592680 @default.
- W2945851246 hasConcept C2778004101 @default.
- W2945851246 hasConcept C2778784160 @default.
- W2945851246 hasConcept C2780795997 @default.
- W2945851246 hasConcept C2780829032 @default.
- W2945851246 hasConcept C48349386 @default.
- W2945851246 hasConcept C519581460 @default.
- W2945851246 hasConcept C55493867 @default.
- W2945851246 hasConcept C86803240 @default.
- W2945851246 hasConceptScore W2945851246C12554922 @default.
- W2945851246 hasConceptScore W2945851246C178790620 @default.
- W2945851246 hasConceptScore W2945851246C181199279 @default.
- W2945851246 hasConceptScore W2945851246C185592680 @default.
- W2945851246 hasConceptScore W2945851246C2778004101 @default.
- W2945851246 hasConceptScore W2945851246C2778784160 @default.
- W2945851246 hasConceptScore W2945851246C2780795997 @default.
- W2945851246 hasConceptScore W2945851246C2780829032 @default.
- W2945851246 hasConceptScore W2945851246C48349386 @default.
- W2945851246 hasConceptScore W2945851246C519581460 @default.
- W2945851246 hasConceptScore W2945851246C55493867 @default.
- W2945851246 hasConceptScore W2945851246C86803240 @default.
- W2945851246 hasLocation W29458512461 @default.
- W2945851246 hasLocation W29458512462 @default.
- W2945851246 hasOpenAccess W2945851246 @default.
- W2945851246 hasPrimaryLocation W29458512461 @default.
- W2945851246 hasRelatedWork W1968134458 @default.
- W2945851246 hasRelatedWork W2038547315 @default.
- W2945851246 hasRelatedWork W2038615667 @default.