FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945896264> ?p ?o ?g. }

• W2945896264 abstract "Abstract Appendage patterning and evolution have been active areas of inquiry for the past two centuries. While most work has centered on the skeleton, particularly that of amniotes, the evolutionary origins and molecular underpinnings of the neuromuscular diversity of fish appendages have remained enigmatic. The fundamental pattern of segmentation in amniotes, for example, is that all muscle precursors and spinal nerves enter either the paired appendages or body wall at the same spinal level. The condition in finned vertebrates is not understood. To address this gap in knowledge, we investigated the development of muscles and nerves in unpaired and paired fins of skates and compared them to those of chain catsharks. During skate and shark embryogenesis, cell populations of muscle precursors and associated spinal nerves at the same axial level contribute to both appendages and body wall, perhaps representing an ancestral condition of gnathostome appendicular neuromuscular systems. Remarkably in skates, this neuromuscular bifurcation as well as colinear Hox expression extend posteriorly to pattern a broad paired fin domain. In addition, we identified migratory muscle precursors (MMPs), which are known to develop into paired appendage muscles with Pax3 and Lbx1 gene expression, in the dorsal fins of skates. Our results suggest that muscles of paired fins have evolved via redeployment of the genetic program of MMPs that were already involved in dorsal fin development. Appendicular neuromuscular systems most likely have emerged as side branches of body wall neuromusculature and have been modified to adapt to distinct aquatic and terrestrial habitats." @default.
• W2945896264 created "2019-05-29" @default.
• W2945896264 creator A5016063341 @default.
• W2945896264 creator A5024618681 @default.
• W2945896264 creator A5028735039 @default.
• W2945896264 creator A5038066522 @default.
• W2945896264 creator A5038361399 @default.
• W2945896264 creator A5065717281 @default.
• W2945896264 creator A5066990764 @default.
• W2945896264 creator A5068022287 @default.
• W2945896264 date "2019-05-21" @default.
• W2945896264 modified "2023-09-26" @default.
• W2945896264 title "The evolutionary origins and diversity of the neuromuscular system of paired appendages in batoids" @default.
• W2945896264 cites W1510855520 @default.
• W2945896264 cites W1518124127 @default.
• W2945896264 cites W1552592481 @default.
• W2945896264 cites W1569416402 @default.
• W2945896264 cites W1756743071 @default.
• W2945896264 cites W1855261343 @default.
• W2945896264 cites W1856994936 @default.
• W2945896264 cites W1944377017 @default.
• W2945896264 cites W1990786422 @default.
• W2945896264 cites W1992655496 @default.
• W2945896264 cites W2003669953 @default.
• W2945896264 cites W2007875088 @default.
• W2945896264 cites W2008646601 @default.
• W2945896264 cites W2022538644 @default.
• W2945896264 cites W2027720945 @default.
• W2945896264 cites W2035988432 @default.
• W2945896264 cites W2045937790 @default.
• W2945896264 cites W2053431317 @default.
• W2945896264 cites W2058721535 @default.
• W2945896264 cites W2075835549 @default.
• W2945896264 cites W2083368559 @default.
• W2945896264 cites W2084658940 @default.
• W2945896264 cites W2094746228 @default.
• W2945896264 cites W2103841961 @default.
• W2945896264 cites W2106081693 @default.
• W2945896264 cites W2124800909 @default.
• W2945896264 cites W2128665076 @default.
• W2945896264 cites W2146340890 @default.
• W2945896264 cites W2148004037 @default.
• W2945896264 cites W2148591887 @default.
• W2945896264 cites W2152415900 @default.
• W2945896264 cites W2166691809 @default.
• W2945896264 cites W2196178080 @default.
• W2945896264 cites W2503935562 @default.
• W2945896264 cites W2753769089 @default.
• W2945896264 cites W2757747178 @default.
• W2945896264 cites W2787025689 @default.
• W2945896264 cites W2794420598 @default.
• W2945896264 cites W2809569418 @default.
• W2945896264 cites W2894335751 @default.
• W2945896264 cites W4237515889 @default.
• W2945896264 cites W52904146 @default.
• W2945896264 doi "https://doi.org/10.1101/644062" @default.
• W2945896264 hasPublicationYear "2019" @default.
• W2945896264 type Work @default.
• W2945896264 sameAs 2945896264 @default.
• W2945896264 citedByCount "1" @default.
• W2945896264 countsByYear W29458962642020 @default.
• W2945896264 crossrefType "posted-content" @default.
• W2945896264 hasAuthorship W2945896264A5016063341 @default.
• W2945896264 hasAuthorship W2945896264A5024618681 @default.
• W2945896264 hasAuthorship W2945896264A5028735039 @default.
• W2945896264 hasAuthorship W2945896264A5038066522 @default.
• W2945896264 hasAuthorship W2945896264A5038361399 @default.
• W2945896264 hasAuthorship W2945896264A5065717281 @default.
• W2945896264 hasAuthorship W2945896264A5066990764 @default.
• W2945896264 hasAuthorship W2945896264A5068022287 @default.
• W2945896264 hasBestOaLocation W29458962642 @default.
• W2945896264 hasConcept C104317684 @default.
• W2945896264 hasConcept C105702510 @default.
• W2945896264 hasConcept C111039654 @default.
• W2945896264 hasConcept C150194340 @default.
• W2945896264 hasConcept C2777971045 @default.
• W2945896264 hasConcept C2779535977 @default.
• W2945896264 hasConcept C41451933 @default.
• W2945896264 hasConcept C54355233 @default.
• W2945896264 hasConcept C78458016 @default.
• W2945896264 hasConcept C86803240 @default.
• W2945896264 hasConceptScore W2945896264C104317684 @default.
• W2945896264 hasConceptScore W2945896264C105702510 @default.
• W2945896264 hasConceptScore W2945896264C111039654 @default.
• W2945896264 hasConceptScore W2945896264C150194340 @default.
• W2945896264 hasConceptScore W2945896264C2777971045 @default.
• W2945896264 hasConceptScore W2945896264C2779535977 @default.
• W2945896264 hasConceptScore W2945896264C41451933 @default.
• W2945896264 hasConceptScore W2945896264C54355233 @default.
• W2945896264 hasConceptScore W2945896264C78458016 @default.
• W2945896264 hasConceptScore W2945896264C86803240 @default.
• W2945896264 hasLocation W29458962641 @default.
• W2945896264 hasLocation W29458962642 @default.
• W2945896264 hasOpenAccess W2945896264 @default.
• W2945896264 hasPrimaryLocation W29458962641 @default.
• W2945896264 hasRelatedWork W1921205358 @default.
• W2945896264 hasRelatedWork W2009232589 @default.
• W2945896264 hasRelatedWork W2033588416 @default.
• W2945896264 hasRelatedWork W2037763886 @default.
• W2945896264 hasRelatedWork W2117675834 @default.

• next