Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945954835> ?p ?o ?g. }
- W2945954835 endingPage "245" @default.
- W2945954835 startingPage "245" @default.
- W2945954835 abstract "Brain tumors are characterized by very high mortality and, despite the continuous research on new pharmacological interventions, little therapeutic progress has been made. One of the main obstacles to improve current treatments is represented by the impermeability of the blood vessels residing within nervous tissue as well as of the new vascular net generating from the tumor, commonly referred to as blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB), respectively. In this review, we focused on established and emerging strategies to overcome the blood-brain barrier to increase drug delivery for brain cancer. To date, there are three broad strategies being investigated to cross the brain vascular wall and they are conceived to breach, bypass, and negotiate the access to the nervous tissue. In this paper, we summarized these approaches highlighting their working mechanism and their potential impact on the quality of life of the patients as well as their current status of development." @default.
- W2945954835 created "2019-05-29" @default.
- W2945954835 creator A5027876593 @default.
- W2945954835 creator A5039644191 @default.
- W2945954835 creator A5046455735 @default.
- W2945954835 creator A5055136443 @default.
- W2945954835 creator A5055215875 @default.
- W2945954835 creator A5061878759 @default.
- W2945954835 date "2019-05-24" @default.
- W2945954835 modified "2023-10-06" @default.
- W2945954835 title "Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer" @default.
- W2945954835 cites W1080555917 @default.
- W2945954835 cites W1869095327 @default.
- W2945954835 cites W1882450096 @default.
- W2945954835 cites W1954742983 @default.
- W2945954835 cites W1963843820 @default.
- W2945954835 cites W1968054359 @default.
- W2945954835 cites W1970780449 @default.
- W2945954835 cites W1971964492 @default.
- W2945954835 cites W1972526066 @default.
- W2945954835 cites W1977583235 @default.
- W2945954835 cites W1978880198 @default.
- W2945954835 cites W1979524509 @default.
- W2945954835 cites W1986129921 @default.
- W2945954835 cites W1991549205 @default.
- W2945954835 cites W1992758695 @default.
- W2945954835 cites W1993077697 @default.
- W2945954835 cites W1996574563 @default.
- W2945954835 cites W1996827572 @default.
- W2945954835 cites W2008625318 @default.
- W2945954835 cites W2010444608 @default.
- W2945954835 cites W2011043218 @default.
- W2945954835 cites W2015541518 @default.
- W2945954835 cites W2015613327 @default.
- W2945954835 cites W2018121350 @default.
- W2945954835 cites W2024572858 @default.
- W2945954835 cites W2025061302 @default.
- W2945954835 cites W2026889493 @default.
- W2945954835 cites W2031969926 @default.
- W2945954835 cites W2034854030 @default.
- W2945954835 cites W2037261041 @default.
- W2945954835 cites W2039167592 @default.
- W2945954835 cites W2040972896 @default.
- W2945954835 cites W2045228120 @default.
- W2945954835 cites W2045600222 @default.
- W2945954835 cites W2049006254 @default.
- W2945954835 cites W2049326508 @default.
- W2945954835 cites W2050589760 @default.
- W2945954835 cites W2055492146 @default.
- W2945954835 cites W2055909692 @default.
- W2945954835 cites W2056856515 @default.
- W2945954835 cites W2063845929 @default.
- W2945954835 cites W2067076937 @default.
- W2945954835 cites W2068069968 @default.
- W2945954835 cites W2070573684 @default.
- W2945954835 cites W2072273122 @default.
- W2945954835 cites W2078402665 @default.
- W2945954835 cites W2088093158 @default.
- W2945954835 cites W2094713052 @default.
- W2945954835 cites W2094779995 @default.
- W2945954835 cites W2095612853 @default.
- W2945954835 cites W2096287682 @default.
- W2945954835 cites W2096338956 @default.
- W2945954835 cites W2104567497 @default.
- W2945954835 cites W2105437215 @default.
- W2945954835 cites W2107427650 @default.
- W2945954835 cites W2109699895 @default.
- W2945954835 cites W2113472355 @default.
- W2945954835 cites W2114544688 @default.
- W2945954835 cites W2122920174 @default.
- W2945954835 cites W2125411036 @default.
- W2945954835 cites W2125640458 @default.
- W2945954835 cites W2133171074 @default.
- W2945954835 cites W2137145251 @default.
- W2945954835 cites W2143127317 @default.
- W2945954835 cites W2143628582 @default.
- W2945954835 cites W2148278891 @default.
- W2945954835 cites W2158757066 @default.
- W2945954835 cites W2160948178 @default.
- W2945954835 cites W2167454336 @default.
- W2945954835 cites W2174049160 @default.
- W2945954835 cites W2198267160 @default.
- W2945954835 cites W2202001486 @default.
- W2945954835 cites W2236460107 @default.
- W2945954835 cites W2256579886 @default.
- W2945954835 cites W2257175382 @default.
- W2945954835 cites W2280490150 @default.
- W2945954835 cites W2280904264 @default.
- W2945954835 cites W2284330471 @default.
- W2945954835 cites W2288753232 @default.
- W2945954835 cites W2295807570 @default.
- W2945954835 cites W2312261107 @default.
- W2945954835 cites W2314371091 @default.
- W2945954835 cites W2333399485 @default.
- W2945954835 cites W2333671040 @default.
- W2945954835 cites W2337125676 @default.
- W2945954835 cites W2337239674 @default.
- W2945954835 cites W2340392977 @default.