FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945978047> ?p ?o ?g. }

• W2945978047 endingPage "1597" @default.
• W2945978047 startingPage "1587" @default.
• W2945978047 abstract "Multiple sclerosis is a disease with a highly variable incidence worldwide. While knowledge about multiple sclerosis risk factors has grown over the years, the aetiology of multiple sclerosis has still not been fully established. We examined multiple sclerosis incidence rates among first-generation immigrants in Denmark, a high-incidence country, and their Danish-born children (second-generation immigrants), to evaluate the importance and timing of exposure to environmental factors in the aetiology of multiple sclerosis. By means of the Danish Civil Registration System we identified 9 121 187 individuals living in Denmark between 1968 and 2015, including 1 176 419 first-generation and 184 282 second-generation immigrants. Study participants were followed for multiple sclerosis in the Danish Multiple Sclerosis Registry from 1968 to 2015. The relative risk (RR) of multiple sclerosis according to immigration status was estimated by means of multiple sclerosis incidence rate ratios obtained in log-linear Poisson regression analysis. Altogether, 16 905 cases of multiple sclerosis were identified in the study cohort, 578 among first-generation and 106 among second-generation immigrants. Multiple sclerosis risk among first-generation immigrants whose parents were born in low, intermediate and high multiple sclerosis risk areas were 21% (RR = 0.21; 95% CI: 0.16-0.28), 43% (RR = 0.43; 95% CI: 0.36-0.50) and 75% (RR = 0.75; 95% CI: 0.67-0.83), respectively, of that among ethnic Danes (test for trend P < 0.0001). First-generation immigrants arriving in Denmark before age 15 years had a multiple sclerosis risk higher than that in their country of birth but lower than that in Denmark, reaching on average 69% of the multiple sclerosis risk among ethnic Danes (RR = 0.69; 95% CI: 0.55-0.87). Multiple sclerosis risk among individuals who came to Denmark at a later age remained closer to that of their country of birth, corresponding to 45% of the multiple sclerosis risk among ethnic Danes (RR = 0.45; 95% CI: 0.41-0.49). Our study supports the idea that environmental factors exerting their role in childhood or adolescence may be of aetiological relevance in multiple sclerosis." @default.
• W2945978047 created "2019-05-29" @default.
• W2945978047 creator A5001189522 @default.
• W2945978047 creator A5004151210 @default.
• W2945978047 creator A5008860248 @default.
• W2945978047 creator A5013331226 @default.
• W2945978047 creator A5025641135 @default.
• W2945978047 creator A5048295558 @default.
• W2945978047 creator A5086472820 @default.
• W2945978047 creator A5091593119 @default.
• W2945978047 date "2019-05-13" @default.
• W2945978047 modified "2023-10-12" @default.
• W2945978047 title "Multiple sclerosis among first- and second-generation immigrants in Denmark: a population-based cohort study" @default.
• W2945978047 cites W1565863844 @default.
• W2945978047 cites W1592537718 @default.
• W2945978047 cites W1974373338 @default.
• W2945978047 cites W1989031673 @default.
• W2945978047 cites W1992069851 @default.
• W2945978047 cites W1993203793 @default.
• W2945978047 cites W1993851261 @default.
• W2945978047 cites W1996574756 @default.
• W2945978047 cites W2007559948 @default.
• W2945978047 cites W2007785782 @default.
• W2945978047 cites W2012398968 @default.
• W2945978047 cites W2013432990 @default.
• W2945978047 cites W2014127183 @default.
• W2945978047 cites W2015679429 @default.
• W2945978047 cites W2018006483 @default.
• W2945978047 cites W2020981313 @default.
• W2945978047 cites W2026624538 @default.
• W2945978047 cites W2031363516 @default.
• W2945978047 cites W2040796341 @default.
• W2945978047 cites W2043264873 @default.
• W2945978047 cites W2046451999 @default.
• W2945978047 cites W2049025913 @default.
• W2945978047 cites W2059289056 @default.
• W2945978047 cites W2067633002 @default.
• W2945978047 cites W2073991570 @default.
• W2945978047 cites W2074805451 @default.
• W2945978047 cites W2080855922 @default.
• W2945978047 cites W2094898093 @default.
• W2945978047 cites W2105548401 @default.
• W2945978047 cites W2127868028 @default.
• W2945978047 cites W2128111832 @default.
• W2945978047 cites W2129841469 @default.
• W2945978047 cites W2137086934 @default.
• W2945978047 cites W2139113477 @default.
• W2945978047 cites W2139362398 @default.
• W2945978047 cites W2143190857 @default.
• W2945978047 cites W2145015886 @default.
• W2945978047 cites W2149218665 @default.
• W2945978047 cites W2156496115 @default.
• W2945978047 cites W2160924282 @default.
• W2945978047 cites W2216975656 @default.
• W2945978047 cites W2275079045 @default.
• W2945978047 cites W2288234740 @default.
• W2945978047 cites W2345998455 @default.
• W2945978047 cites W2514611781 @default.
• W2945978047 cites W2527832785 @default.
• W2945978047 cites W2792140778 @default.
• W2945978047 cites W2799594477 @default.
• W2945978047 cites W30533055 @default.
• W2945978047 cites W4211003420 @default.
• W2945978047 doi "https://doi.org/10.1093/brain/awz088" @default.
• W2945978047 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31081503" @default.
• W2945978047 hasPublicationYear "2019" @default.
• W2945978047 type Work @default.
• W2945978047 sameAs 2945978047 @default.
• W2945978047 citedByCount "29" @default.
• W2945978047 countsByYear W29459780472019 @default.
• W2945978047 countsByYear W29459780472020 @default.
• W2945978047 countsByYear W29459780472021 @default.
• W2945978047 countsByYear W29459780472022 @default.
• W2945978047 countsByYear W29459780472023 @default.
• W2945978047 crossrefType "journal-article" @default.
• W2945978047 hasAuthorship W2945978047A5001189522 @default.
• W2945978047 hasAuthorship W2945978047A5004151210 @default.
• W2945978047 hasAuthorship W2945978047A5008860248 @default.
• W2945978047 hasAuthorship W2945978047A5013331226 @default.
• W2945978047 hasAuthorship W2945978047A5025641135 @default.
• W2945978047 hasAuthorship W2945978047A5048295558 @default.
• W2945978047 hasAuthorship W2945978047A5086472820 @default.
• W2945978047 hasAuthorship W2945978047A5091593119 @default.
• W2945978047 hasBestOaLocation W29459780471 @default.
• W2945978047 hasConcept C120665830 @default.
• W2945978047 hasConcept C121332964 @default.
• W2945978047 hasConcept C126322002 @default.
• W2945978047 hasConcept C137627325 @default.
• W2945978047 hasConcept C138885662 @default.
• W2945978047 hasConcept C144024400 @default.
• W2945978047 hasConcept C149923435 @default.
• W2945978047 hasConcept C164622146 @default.
• W2945978047 hasConcept C166957645 @default.
• W2945978047 hasConcept C187212893 @default.
• W2945978047 hasConcept C201903717 @default.
• W2945978047 hasConcept C203014093 @default.
• W2945978047 hasConcept C205649164 @default.
• W2945978047 hasConcept C2780640218 @default.

• next