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• W2945980358 abstract "Air pollution is a risk factor for cardiovascular and respiratory morbidity and mortality. A growing literature also links exposure to diverse air pollutants (e.g., nanoparticles, particulate matter, ozone, traffic-related air pollution) with brain health, including increased incidence of neurological and psychiatric disorders such as cognitive decline, dementia (including Alzheimer's disease), anxiety, depression, and suicide. A critical gap in our understanding of adverse impacts of pollutants on the central nervous system (CNS) is the early initiating events triggered by pollutant inhalation that contribute to disease progression. Recent experimental evidence has shown that particulate matter and ozone, two common pollutants with differing characteristics and reactivity, can activate the hypothalamic-pituitary-adrenal (HPA) axis and release glucocorticoid stress hormones (cortisol in humans, corticosterone in rodents) as part of a neuroendocrine stress response. The brain is highly sensitive to stress: stress hormones affect cognition and mental health, and chronic stress can produce profound biochemical and structural changes in the brain. Chronic activation and/or dysfunction of the HPA axis also increases the burden on physiological stress response systems, conceptualized as allostatic load, and is a common pathway implicated in many diseases. The present paper provides an overview of how systemic stress-dependent biological responses common to particulate matter and ozone may provide insight into early CNS effects of pollutants, including links with oxidative, inflammatory, and metabolic processes. Evidence of pollutant effect modification by non-chemical stressors (e.g., socioeconomic position, psychosocial, noise), age (prenatal to elderly), and sex will also be reviewed in the context of susceptibility across the lifespan." @default.
• W2945980358 created "2019-05-29" @default.
• W2945980358 creator A5038066341 @default.
• W2945980358 date "2019-06-04" @default.
• W2945980358 modified "2023-10-14" @default.
• W2945980358 title "Air Pollution, Stress, and Allostatic Load: Linking Systemic and Central Nervous System Impacts" @default.
• W2945980358 cites W1667826107 @default.
• W2945980358 cites W1732425222 @default.
• W2945980358 cites W1830298985 @default.
• W2945980358 cites W1895530546 @default.
• W2945980358 cites W1950878272 @default.
• W2945980358 cites W1963629744 @default.
• W2945980358 cites W1964621949 @default.
• W2945980358 cites W1966344268 @default.
• W2945980358 cites W1970549184 @default.
• W2945980358 cites W1972101843 @default.
• W2945980358 cites W1972157243 @default.
• W2945980358 cites W1973086812 @default.
• W2945980358 cites W1975118075 @default.
• W2945980358 cites W1977143695 @default.
• W2945980358 cites W1978883267 @default.
• W2945980358 cites W1978891587 @default.
• W2945980358 cites W1981496519 @default.
• W2945980358 cites W1981824987 @default.
• W2945980358 cites W1982795519 @default.
• W2945980358 cites W1982835526 @default.
• W2945980358 cites W1987375729 @default.
• W2945980358 cites W1989102218 @default.
• W2945980358 cites W1989771767 @default.
• W2945980358 cites W1990362540 @default.
• W2945980358 cites W1991346214 @default.
• W2945980358 cites W1994628299 @default.
• W2945980358 cites W1997147328 @default.
• W2945980358 cites W1997774266 @default.
• W2945980358 cites W2001304703 @default.
• W2945980358 cites W2002561201 @default.
• W2945980358 cites W2006103193 @default.
• W2945980358 cites W2007674835 @default.
• W2945980358 cites W2008050722 @default.
• W2945980358 cites W2009064331 @default.
• W2945980358 cites W2009149639 @default.
• W2945980358 cites W2010453317 @default.
• W2945980358 cites W2013058211 @default.
• W2945980358 cites W2013208969 @default.
• W2945980358 cites W2014711343 @default.
• W2945980358 cites W2015252215 @default.
• W2945980358 cites W2019806189 @default.
• W2945980358 cites W2021688937 @default.
• W2945980358 cites W2022139094 @default.
• W2945980358 cites W2025105246 @default.
• W2945980358 cites W2025475816 @default.
• W2945980358 cites W2027956144 @default.
• W2945980358 cites W2029630254 @default.
• W2945980358 cites W2032146145 @default.
• W2945980358 cites W2033948248 @default.
• W2945980358 cites W2039661452 @default.
• W2945980358 cites W2040225362 @default.
• W2945980358 cites W2043090378 @default.
• W2945980358 cites W2047906382 @default.
• W2945980358 cites W2050976940 @default.
• W2945980358 cites W2054077939 @default.
• W2945980358 cites W2054433070 @default.
• W2945980358 cites W2054543840 @default.
• W2945980358 cites W2054886307 @default.
• W2945980358 cites W2057310315 @default.
• W2945980358 cites W2058091800 @default.
• W2945980358 cites W2060644077 @default.
• W2945980358 cites W2062242070 @default.
• W2945980358 cites W2063664113 @default.
• W2945980358 cites W2065195236 @default.
• W2945980358 cites W2071173492 @default.
• W2945980358 cites W2076507733 @default.
• W2945980358 cites W2076517751 @default.
• W2945980358 cites W2083199038 @default.
• W2945980358 cites W2086697336 @default.
• W2945980358 cites W2090985202 @default.
• W2945980358 cites W2091164849 @default.
• W2945980358 cites W2094319942 @default.
• W2945980358 cites W2097183694 @default.
• W2945980358 cites W2097529540 @default.
• W2945980358 cites W2097775881 @default.
• W2945980358 cites W2104386411 @default.
• W2945980358 cites W2107331939 @default.
• W2945980358 cites W2108344016 @default.
• W2945980358 cites W2109403278 @default.
• W2945980358 cites W2117579257 @default.
• W2945980358 cites W2118548611 @default.
• W2945980358 cites W2118620344 @default.
• W2945980358 cites W2122878567 @default.
• W2945980358 cites W2127435517 @default.
• W2945980358 cites W2129409176 @default.
• W2945980358 cites W2129478045 @default.
• W2945980358 cites W2130261616 @default.
• W2945980358 cites W2134033459 @default.
• W2945980358 cites W2135281606 @default.
• W2945980358 cites W2137338071 @default.
• W2945980358 cites W2141463840 @default.
• W2945980358 cites W2148856081 @default.

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