FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2945999190> ?p ?o ?g. }

• W2945999190 endingPage "809" @default.
• W2945999190 startingPage "801" @default.
• W2945999190 abstract "A new nontoxic porous In III ‐based metal‐organic framework [In(Hpbic)(pbic)](DMF) 2 ( 1 ) (DMF = N , N ‐dimethylacetamide) was successfully prepared with 2‐(pyridin‐4‐yl)‐1H‐benzo[d]imidazole‐5‐carboxylic acid (H 2 pbic) as organic linker via a solvothermal process. Further, the nanostructure 1 could be obtained via a green grinding method. Nitrogen adsorption measurements revealed the presence of micropores as well as moderate high BET surface areas in the activated nanostructure 1 ( 1a ). The drug loading experiment shows that 5‐fluorouracil (5‐Fu) is preferentially captured into the pore of the nanostructure 1a with a loading capacity of 32.6 %. Meanwhile, the controlled release of 5‐Fu in a simulated human body with liquid phosphate‐buffered saline solution was realized. In addition, the Cell Counting Kit‐8 (CCK‐8) assay was conducted to determine the inhibitory effect of 5‐Fu@ 1a on human colon cancer cell SW60 viability and proliferation, the results indicated the excellent anti‐cancer activity of 5‐Fu@ 1a in vitro. To reveal the related mechanism, the Annexin V‐FITC/PI assay and reactive oxygen species (ROS) level detection was carried out after 5‐Fu@ 1a treatment. Finally, the in vivo xenograft model was constructed in mice, the tumor volume, and mice body weight were recording at indicated time. The in vivo results suggested the significant inhibitory activity of 5‐Fu@ 1a in mice." @default.
• W2945999190 created "2019-05-29" @default.
• W2945999190 creator A5034621106 @default.
• W2945999190 creator A5040597446 @default.
• W2945999190 creator A5070017918 @default.
• W2945999190 creator A5079555036 @default.
• W2945999190 date "2019-05-17" @default.
• W2945999190 modified "2023-09-27" @default.
• W2945999190 title "A In^III -MOF with Imidazole Decorated Pores as 5-Fu Delivery System to Inhibit Colon Cancer Cells Proliferation and Induce Cell Apoptosis in vitro and in vivo" @default.
• W2945999190 cites W1778497012 @default.
• W2945999190 cites W1829327035 @default.
• W2945999190 cites W1969360633 @default.
• W2945999190 cites W1970753581 @default.
• W2945999190 cites W1995995697 @default.
• W2945999190 cites W1996352962 @default.
• W2945999190 cites W2020402378 @default.
• W2945999190 cites W2027009776 @default.
• W2945999190 cites W2032943162 @default.
• W2945999190 cites W2059205366 @default.
• W2945999190 cites W2066685510 @default.
• W2945999190 cites W2094816761 @default.
• W2945999190 cites W2098292174 @default.
• W2945999190 cites W2102449174 @default.
• W2945999190 cites W2170811673 @default.
• W2945999190 cites W2265944944 @default.
• W2945999190 cites W2465873334 @default.
• W2945999190 cites W2556634698 @default.
• W2945999190 cites W2737608110 @default.
• W2945999190 cites W2766680394 @default.
• W2945999190 cites W2793177201 @default.
• W2945999190 cites W2885631997 @default.
• W2945999190 cites W2888262690 @default.
• W2945999190 cites W2897515023 @default.
• W2945999190 cites W2901122739 @default.
• W2945999190 cites W2902828964 @default.
• W2945999190 cites W2906269708 @default.
• W2945999190 cites W2912487485 @default.
• W2945999190 cites W2917837889 @default.
• W2945999190 cites W2929866107 @default.
• W2945999190 cites W2937972896 @default.
• W2945999190 doi "https://doi.org/10.1002/zaac.201900072" @default.
• W2945999190 hasPublicationYear "2019" @default.
• W2945999190 type Work @default.
• W2945999190 sameAs 2945999190 @default.
• W2945999190 citedByCount "7" @default.
• W2945999190 countsByYear W29459991902019 @default.
• W2945999190 countsByYear W29459991902020 @default.
• W2945999190 countsByYear W29459991902021 @default.
• W2945999190 countsByYear W29459991902022 @default.
• W2945999190 countsByYear W29459991902023 @default.
• W2945999190 crossrefType "journal-article" @default.
• W2945999190 hasAuthorship W2945999190A5034621106 @default.
• W2945999190 hasAuthorship W2945999190A5040597446 @default.
• W2945999190 hasAuthorship W2945999190A5070017918 @default.
• W2945999190 hasAuthorship W2945999190A5079555036 @default.
• W2945999190 hasConcept C109316439 @default.
• W2945999190 hasConcept C121608353 @default.
• W2945999190 hasConcept C12554922 @default.
• W2945999190 hasConcept C150903083 @default.
• W2945999190 hasConcept C178790620 @default.
• W2945999190 hasConcept C185592680 @default.
• W2945999190 hasConcept C190283241 @default.
• W2945999190 hasConcept C202751555 @default.
• W2945999190 hasConcept C207001950 @default.
• W2945999190 hasConcept C2779820397 @default.
• W2945999190 hasConcept C53227056 @default.
• W2945999190 hasConcept C54355233 @default.
• W2945999190 hasConcept C55493867 @default.
• W2945999190 hasConcept C86803240 @default.
• W2945999190 hasConcept C88634738 @default.
• W2945999190 hasConcept C96232424 @default.
• W2945999190 hasConceptScore W2945999190C109316439 @default.
• W2945999190 hasConceptScore W2945999190C121608353 @default.
• W2945999190 hasConceptScore W2945999190C12554922 @default.
• W2945999190 hasConceptScore W2945999190C150903083 @default.
• W2945999190 hasConceptScore W2945999190C178790620 @default.
• W2945999190 hasConceptScore W2945999190C185592680 @default.
• W2945999190 hasConceptScore W2945999190C190283241 @default.
• W2945999190 hasConceptScore W2945999190C202751555 @default.
• W2945999190 hasConceptScore W2945999190C207001950 @default.
• W2945999190 hasConceptScore W2945999190C2779820397 @default.
• W2945999190 hasConceptScore W2945999190C53227056 @default.
• W2945999190 hasConceptScore W2945999190C54355233 @default.
• W2945999190 hasConceptScore W2945999190C55493867 @default.
• W2945999190 hasConceptScore W2945999190C86803240 @default.
• W2945999190 hasConceptScore W2945999190C88634738 @default.
• W2945999190 hasConceptScore W2945999190C96232424 @default.
• W2945999190 hasIssue "11" @default.
• W2945999190 hasLocation W29459991901 @default.
• W2945999190 hasOpenAccess W2945999190 @default.
• W2945999190 hasPrimaryLocation W29459991901 @default.
• W2945999190 hasRelatedWork W1982027601 @default.
• W2945999190 hasRelatedWork W200909032 @default.
• W2945999190 hasRelatedWork W2371556958 @default.
• W2945999190 hasRelatedWork W2378294407 @default.
• W2945999190 hasRelatedWork W2384114661 @default.
• W2945999190 hasRelatedWork W2416964709 @default.
• W2945999190 hasRelatedWork W2464301138 @default.

• next