Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946018889> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2946018889 abstract "The risk of atherosclerotic cardiovascular disease (ASCVD) is estimated using the American College of Cardiology (ACC)/American Heart Association (AHA) Pooled Cohort Equations (PCEs). However, the accuracy of this tool remains controversial, particularly among patients who are recommended statin therapy according to the ACC/AHA guidelines. We performed external validation of PCEs among patients eligible for statin therapy using data from the systolic blood pressure intervention trial (SPRINT).Our study included 4057 patients from among the 9361 patients in SPRINT. The mean patient age was 64.5 years, and the median predicted 10-year risks of ASCVD were 17.2% and 12.3% for men and women, respectively. Over a median follow-up of 3.3 years, 133 primary events (including 23 cardiovascular deaths) were noted, whereas 304 events were predicted by the PCEs. The PCEs demonstrated poor calibration (Hosmer-Lemeshow test, p < 0.001) and overestimated the probability consistently. Additionally, they showed moderate discrimination [area under the curve: 0.65 (95% confidence interval, 0.60-0.69)]. This study demonstrates that PCEs might overestimate the risk of ASCVD in patients who are recommended statin therapy." @default.
- W2946018889 created "2019-05-29" @default.
- W2946018889 creator A5023463037 @default.
- W2946018889 creator A5033245538 @default.
- W2946018889 creator A5036103653 @default.
- W2946018889 creator A5039593848 @default.
- W2946018889 creator A5080215688 @default.
- W2946018889 date "2019-05-14" @default.
- W2946018889 modified "2023-10-11" @default.
- W2946018889 title "External validation of pooled cohort equations using systolic blood pressure intervention trial data" @default.
- W2946018889 cites W1975897418 @default.
- W2946018889 cites W2054400785 @default.
- W2946018889 cites W2096849439 @default.
- W2946018889 cites W2156097706 @default.
- W2946018889 cites W2168536722 @default.
- W2946018889 cites W2346445964 @default.
- W2946018889 cites W2346592209 @default.
- W2946018889 cites W2560543780 @default.
- W2946018889 cites W2565094539 @default.
- W2946018889 cites W2805499342 @default.
- W2946018889 cites W2884679826 @default.
- W2946018889 cites W3025479223 @default.
- W2946018889 cites W3150595609 @default.
- W2946018889 doi "https://doi.org/10.1186/s13104-019-4293-1" @default.
- W2946018889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6518641" @default.
- W2946018889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31088530" @default.
- W2946018889 hasPublicationYear "2019" @default.
- W2946018889 type Work @default.
- W2946018889 sameAs 2946018889 @default.
- W2946018889 citedByCount "6" @default.
- W2946018889 countsByYear W29460188892019 @default.
- W2946018889 countsByYear W29460188892020 @default.
- W2946018889 countsByYear W29460188892021 @default.
- W2946018889 countsByYear W29460188892022 @default.
- W2946018889 crossrefType "journal-article" @default.
- W2946018889 hasAuthorship W2946018889A5023463037 @default.
- W2946018889 hasAuthorship W2946018889A5033245538 @default.
- W2946018889 hasAuthorship W2946018889A5036103653 @default.
- W2946018889 hasAuthorship W2946018889A5039593848 @default.
- W2946018889 hasAuthorship W2946018889A5080215688 @default.
- W2946018889 hasBestOaLocation W29460188891 @default.
- W2946018889 hasConcept C126322002 @default.
- W2946018889 hasConcept C164705383 @default.
- W2946018889 hasConcept C1862650 @default.
- W2946018889 hasConcept C2776839432 @default.
- W2946018889 hasConcept C2776868573 @default.
- W2946018889 hasConcept C2779134260 @default.
- W2946018889 hasConcept C2909478654 @default.
- W2946018889 hasConcept C44249647 @default.
- W2946018889 hasConcept C71924100 @default.
- W2946018889 hasConcept C72563966 @default.
- W2946018889 hasConcept C84393581 @default.
- W2946018889 hasConceptScore W2946018889C126322002 @default.
- W2946018889 hasConceptScore W2946018889C164705383 @default.
- W2946018889 hasConceptScore W2946018889C1862650 @default.
- W2946018889 hasConceptScore W2946018889C2776839432 @default.
- W2946018889 hasConceptScore W2946018889C2776868573 @default.
- W2946018889 hasConceptScore W2946018889C2779134260 @default.
- W2946018889 hasConceptScore W2946018889C2909478654 @default.
- W2946018889 hasConceptScore W2946018889C44249647 @default.
- W2946018889 hasConceptScore W2946018889C71924100 @default.
- W2946018889 hasConceptScore W2946018889C72563966 @default.
- W2946018889 hasConceptScore W2946018889C84393581 @default.
- W2946018889 hasIssue "1" @default.
- W2946018889 hasLocation W29460188891 @default.
- W2946018889 hasLocation W29460188892 @default.
- W2946018889 hasLocation W29460188893 @default.
- W2946018889 hasLocation W29460188894 @default.
- W2946018889 hasOpenAccess W2946018889 @default.
- W2946018889 hasPrimaryLocation W29460188891 @default.
- W2946018889 hasRelatedWork W2315085516 @default.
- W2946018889 hasRelatedWork W2475182459 @default.
- W2946018889 hasRelatedWork W2511253458 @default.
- W2946018889 hasRelatedWork W2577408387 @default.
- W2946018889 hasRelatedWork W2584146692 @default.
- W2946018889 hasRelatedWork W2603773853 @default.
- W2946018889 hasRelatedWork W2789861493 @default.
- W2946018889 hasRelatedWork W2896759582 @default.
- W2946018889 hasRelatedWork W4245687206 @default.
- W2946018889 hasRelatedWork W4246211696 @default.
- W2946018889 hasVolume "12" @default.
- W2946018889 isParatext "false" @default.
- W2946018889 isRetracted "false" @default.
- W2946018889 magId "2946018889" @default.
- W2946018889 workType "article" @default.