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- W2946042893 abstract "Introduction: Pulmonary hypertension (PH) secondary to left-sided heart disease (Group 2 PH) is a frequent complication of heart failure (HF) and is a heterogeneous phenotypic disorder that worsens exercise capacity, increases risk for hospitalization and survival independent of left ventricular ejection fraction (LVEF) or stage of HF. Areas covered: In this review, an update of the current knowledge and some potential challenges about the pathophysiology and treatments of group 2 PH in patients with HF of either preserved or reduced ejection fraction are provided. Also, this review discusses the epidemiology and provides hints for the optimal evaluation and diagnosis of these patients to prevent misclassification of their pulmonary hypertension. Expert opinion: There are many of areas lacking knowledge and understanding in the field of pulmonary hypertension associated to left heart disease (PH-LHD) that should be addressed in the future. Further research should be performed, in terms of pathobiology, and understanding the predisposition (genetic susceptibility and contributing factors) of the different phenotypes of this disorder. More clinical trials targeting new therapeutic options and specific PH therapies are warranted to help this increasing important patient group as the current guidelines recommend to only treat the underlying left-sided heart disease." @default.
- W2946042893 created "2019-05-29" @default.
- W2946042893 creator A5006065960 @default.
- W2946042893 date "2019-06-03" @default.
- W2946042893 modified "2023-09-26" @default.
- W2946042893 title "Challenges in pulmonary hypertension associated with left heart disease" @default.
- W2946042893 cites W120579310 @default.
- W2946042893 cites W122121821 @default.
- W2946042893 cites W1690550543 @default.
- W2946042893 cites W1721966521 @default.
- W2946042893 cites W1968632672 @default.
- W2946042893 cites W1974168665 @default.
- W2946042893 cites W1975943347 @default.
- W2946042893 cites W1977018242 @default.
- W2946042893 cites W1977354362 @default.
- W2946042893 cites W1979618547 @default.
- W2946042893 cites W1982451770 @default.
- W2946042893 cites W1982601738 @default.
- W2946042893 cites W1984243104 @default.
- W2946042893 cites W1988287970 @default.
- W2946042893 cites W1991463267 @default.
- W2946042893 cites W1997964739 @default.
- W2946042893 cites W2000411191 @default.
- W2946042893 cites W2000799528 @default.
- W2946042893 cites W2001207343 @default.
- W2946042893 cites W2003150221 @default.
- W2946042893 cites W2007001122 @default.
- W2946042893 cites W2007289750 @default.
- W2946042893 cites W2008435861 @default.
- W2946042893 cites W2008933127 @default.
- W2946042893 cites W2016173867 @default.
- W2946042893 cites W2025252445 @default.
- W2946042893 cites W2026499651 @default.
- W2946042893 cites W2028148874 @default.
- W2946042893 cites W2033557350 @default.
- W2946042893 cites W2033852098 @default.
- W2946042893 cites W2034679503 @default.
- W2946042893 cites W2039656284 @default.
- W2946042893 cites W2043083903 @default.
- W2946042893 cites W2045110714 @default.
- W2946042893 cites W2053775321 @default.
- W2946042893 cites W2055751817 @default.
- W2946042893 cites W2057279296 @default.
- W2946042893 cites W2060126259 @default.
- W2946042893 cites W2060461980 @default.
- W2946042893 cites W2061208405 @default.
- W2946042893 cites W2070022895 @default.
- W2946042893 cites W2073280615 @default.
- W2946042893 cites W2075941589 @default.
- W2946042893 cites W2078325566 @default.
- W2946042893 cites W2090159456 @default.
- W2946042893 cites W2090412678 @default.
- W2946042893 cites W2094219885 @default.
- W2946042893 cites W2095455207 @default.
- W2946042893 cites W2096267219 @default.
- W2946042893 cites W2101806726 @default.
- W2946042893 cites W2103186593 @default.
- W2946042893 cites W2104847567 @default.
- W2946042893 cites W2106646947 @default.
- W2946042893 cites W2110359510 @default.
- W2946042893 cites W2117239217 @default.
- W2946042893 cites W2117259028 @default.
- W2946042893 cites W2119436573 @default.
- W2946042893 cites W2121376498 @default.
- W2946042893 cites W2124759075 @default.
- W2946042893 cites W2128256532 @default.
- W2946042893 cites W2128862255 @default.
- W2946042893 cites W2129800911 @default.
- W2946042893 cites W2134537197 @default.
- W2946042893 cites W2136895657 @default.
- W2946042893 cites W2138091764 @default.
- W2946042893 cites W2138162621 @default.
- W2946042893 cites W2138984082 @default.
- W2946042893 cites W2139041982 @default.
- W2946042893 cites W2141500368 @default.
- W2946042893 cites W2148038451 @default.
- W2946042893 cites W2148437156 @default.
- W2946042893 cites W2148723902 @default.
- W2946042893 cites W2150057452 @default.
- W2946042893 cites W2151618483 @default.
- W2946042893 cites W2152940522 @default.
- W2946042893 cites W2154395080 @default.
- W2946042893 cites W2155135354 @default.
- W2946042893 cites W2161370807 @default.
- W2946042893 cites W2164391088 @default.
- W2946042893 cites W2166504467 @default.
- W2946042893 cites W2166964193 @default.
- W2946042893 cites W2168017932 @default.
- W2946042893 cites W2168896453 @default.
- W2946042893 cites W2178738676 @default.
- W2946042893 cites W2183644045 @default.
- W2946042893 cites W2209002211 @default.
- W2946042893 cites W2332880232 @default.
- W2946042893 cites W2357867448 @default.
- W2946042893 cites W2416228846 @default.
- W2946042893 cites W2472911055 @default.
- W2946042893 cites W2518436669 @default.
- W2946042893 cites W2526299174 @default.