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- W2946068023 abstract "Objective: To evaluate of the Effect of Dexmedetomidine infusion on outcome of COPD patients on non-invasive ventilation. Methods : Enrolled patients were randomly allocated to a (Dexmedetomidine) DEX group A (n=35) or (0.9% saline) control group B (n=35) using a randomized sequence generated by a computer, randomization process was centralized. The participating patients and nurses were blinded to the treatment. Results: Differences in mean blood oxygenation were found to be statistically significant at all the follow up periods. Mean dyspnea grading of Group B (8.51±1.22) was found to be higher than that of Group A (7.09±1.31) and difference in dyspnea grading of both the groups at 1 hr. was found to be statistically significant (p<0.001). Comparison of mean heart rate between two groups showed significant stability in both the groups. ICU stay of patients of Group A ranged from 2-6 days while that of Group B from 9-17 days. Difference in mean ICU stay in patients of Group A (4.37±1.09 days) and Group B (12.23±1.94 days) was found to be statistically highly significant (p<0.001). Conclusion: The desired level of oxygenation and improved outcome obtained by the effect of Dexmedetomidine on Non-invasive ventilation treatment in COPD patients improved many important aspects of critical care compared with the conventional treatment." @default.
- W2946068023 created "2019-05-29" @default.
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- W2946068023 date "2018-07-26" @default.
- W2946068023 modified "2023-09-23" @default.
- W2946068023 title "EVALUATION OF THE EFFECT OF DEXMEDETOMIDINE INFUSION ON OUTCOME OF COPD PATIENTS ON NON-INVASIVE VENTILATION" @default.
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