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• W2946070403 abstract "We have design and synthesized a novel series of chalone fused quinoline derivatives (8a–j), and their structures were c by 1H NMR, 13C NMR, Mass and HRMS spectral analysis. Further, all these derivatives (8a–j) were tested against three human cancer cell lines like MCF-7 (breast), A-549 (lung), and A375 (melanoma). All these newly synthesized compounds (8a–j) were showed moderate to good activity on cell lines. Especially compounds 8b, 8d, 8e, 8g, 8h and 8j exhibits more potent activity than positive control doxorubicin." @default.
• W2946070403 created "2019-05-29" @default.
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• W2946070403 date "2019-08-01" @default.
• W2946070403 modified "2023-10-18" @default.
• W2946070403 title "Synthesis and biological evaluation of chalcone fused quinoline derivatives as anticancer agents" @default.
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• W2946070403 doi "https://doi.org/10.1016/j.cdc.2019.100236" @default.
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