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- W2946111505 abstract "Zanthoxylum nitidum (Roxb.) DC (Rutaceae) is a traditional medicine used for the treatment of various diseases like toothache, gingivitis, fever, colic vomiting, diarrhea, and cholera. Three new alkaloids, zanthocadinanine C (1), 7-methoxy-8-demethoxynitidine (2), and zanthonitiside I (3) were isolated from the stems and twigs of Z. nitidum. Their structures were determined on the basis of extensive spectroscopic, including 1-dimensional and 2-dimensional nuclear magnetic resonance and mass spectroscopy data. Compounds 1–3 were evaluated for cytotoxic activity against 5 human cancer cell lines, KB, MCF-7, LNCaP, HepG-2, and LU-1. Compound 2 showed significant cytotoxic activity against all tested human cancer cell lines with IC 50 values ranging from 10.3 to 12.6 µM." @default.
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- W2946111505 date "2019-05-01" @default.
- W2946111505 modified "2023-09-24" @default.
- W2946111505 title "Alkaloids From <i>Zanthoxylum nitidum</i> and Their Cytotoxic Activity" @default.
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- W2946111505 doi "https://doi.org/10.1177/1934578x19844133" @default.
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