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• W2946140409 abstract "<b><i>Objectives:</i></b> The purpose of the study was to compare the efficacy of a product containing cranberry and propolis (DUAB) to placebo for reducing frequency of cystitis in women with recurrent acute cystitis. <b><i>Method:</i></b> A multicenter, placebo-controlled, randomized study of women aged &#x3e;18 years with at least 4 episodes of cystitis in the previous 12 months was performed. The number of cystitis episodes over a 6-month follow-up was the primary end point. <b><i>Results:</i></b> Forty-two women were included in the cranberry + propolis group, and 43 women were in the placebo group. The mean age was 53 ± 18 years, with 6.2 ± 3.6 cystitis episodes in the previous year, with no differences between the 2 groups. The mean number of infections was lower in the propolis + cranberry group (respectively, 2.3 ± 1.8 vs. 3.1 ± 1.8). The total number of cystitis episodes in the first 3 months was lower in the propolis + cranberry group (0.7 ± 1.1 vs. 1.3 ± 1.1, <i>p</i> = 0.0257) after adjusting for water consumption. The mean time to onset of the first urinary tract infection (UTI) was also significantly longer in the propolis + cranberry group (69.9 ± 45.8 days vs. 43.3 ± 45.9, <i>p</i> = 0.0258). Tolerance to the treatments was good and comparable in both groups. <b><i>Conclusions:</i></b> We demonstrate for the first time that cranberry and propolis supplementation significantly reduces the incidence of UTIs during the first 3 months and delays the onset of an episode of cystitis." @default.
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• W2946140409 date "2019-01-01" @default.
• W2946140409 modified "2023-10-14" @default.
• W2946140409 title "A Multicenter, Randomized, Placebo-Controlled Study Evaluating the Efficacy of a Combination of Propolis and Cranberry (<b><i>Vaccinium macrocarpon</i></b>) (DUAB®) in Preventing Low Urinary Tract Infection Recurrence in Women Complaining of Recurrent Cystitis" @default.
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• W2946140409 doi "https://doi.org/10.1159/000496695" @default.
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