FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946253525> ?p ?o ?g. }

• W2946253525 endingPage "e0216982" @default.
• W2946253525 startingPage "e0216982" @default.
• W2946253525 abstract "White bodies (WB), multilobulated soft tissue that wraps the optic tracts and optic lobes, have been considered the hematopoietic organ of the cephalopods. Its glandular appearance and its lobular morphology suggest that different parts of the WB may perform different functions, but a detailed functional analysis of the octopus WB is lacking. The aim of this study is to describe the transcriptomic profile of WB to better understand its functions, with emphasis on the difference between sexes during reproductive events. Then, validation via qPCR was performed using different tissues to find out tissue-specific transcripts. High differentiation in signaling pathways was observed in the comparison of female and male transcriptomic profiles. For instance, the expression of genes involved in the androgen receptor-signaling pathway were detected only in males, whereas estrogen receptor showed higher expression in females. Highly expressed genes in males enriched oxidation-reduction and apoptotic processes, which are related to the immune response. On the other hand, expression of genes involved in replicative senescence and the response to cortisol were only detected in females. Moreover, the transcripts with higher expression in females enriched a wide variety of signaling pathways mediated by molecules like neuropeptides, integrins, MAPKs and receptors like TNF and Toll-like. In addition, these putative neuropeptide transcripts, showed higher expression in females’ WB and were not detected in other analyzed tissues. These results suggest that the differentiation in signaling pathways in white bodies of O. maya influences the physiological dimorphism between females and males during the reproductive phase." @default.
• W2946253525 created "2019-05-29" @default.
• W2946253525 creator A5000669914 @default.
• W2946253525 creator A5009973821 @default.
• W2946253525 creator A5015134420 @default.
• W2946253525 creator A5019590753 @default.
• W2946253525 creator A5038244972 @default.
• W2946253525 creator A5055541161 @default.
• W2946253525 creator A5082505879 @default.
• W2946253525 date "2019-05-16" @default.
• W2946253525 modified "2023-10-01" @default.
• W2946253525 title "Octopus maya white body show sex-specific transcriptomic profiles during the reproductive phase, with high differentiation in signaling pathways" @default.
• W2946253525 cites W1276594388 @default.
• W2946253525 cites W1500743364 @default.
• W2946253525 cites W1537141047 @default.
• W2946253525 cites W1577577364 @default.
• W2946253525 cites W1609977045 @default.
• W2946253525 cites W1621445074 @default.
• W2946253525 cites W1763057720 @default.
• W2946253525 cites W1899538374 @default.
• W2946253525 cites W1922422480 @default.
• W2946253525 cites W1964897785 @default.
• W2946253525 cites W1978293288 @default.
• W2946253525 cites W1981608797 @default.
• W2946253525 cites W1990900515 @default.
• W2946253525 cites W1998706392 @default.
• W2946253525 cites W1999215612 @default.
• W2946253525 cites W1999412144 @default.
• W2946253525 cites W1999574084 @default.
• W2946253525 cites W1999992132 @default.
• W2946253525 cites W2001247086 @default.
• W2946253525 cites W2001277720 @default.
• W2946253525 cites W2009933687 @default.
• W2946253525 cites W2010868383 @default.
• W2946253525 cites W2011657487 @default.
• W2946253525 cites W2030966943 @default.
• W2946253525 cites W2035151934 @default.
• W2946253525 cites W2035251095 @default.
• W2946253525 cites W2041995882 @default.
• W2946253525 cites W2044545834 @default.
• W2946253525 cites W2045793458 @default.
• W2946253525 cites W2046216444 @default.
• W2946253525 cites W2047475291 @default.
• W2946253525 cites W2049225918 @default.
• W2946253525 cites W2055702706 @default.
• W2946253525 cites W2056833728 @default.
• W2946253525 cites W2060317279 @default.
• W2946253525 cites W2060837467 @default.
• W2946253525 cites W2063526029 @default.
• W2946253525 cites W2064904921 @default.
• W2946253525 cites W2065872027 @default.
• W2946253525 cites W2074192087 @default.
• W2946253525 cites W2074431006 @default.
• W2946253525 cites W2074775280 @default.
• W2946253525 cites W2088326899 @default.
• W2946253525 cites W2093115330 @default.
• W2946253525 cites W2097107826 @default.
• W2946253525 cites W2102054011 @default.
• W2946253525 cites W2104457965 @default.
• W2946253525 cites W2105423509 @default.
• W2946253525 cites W2106781329 @default.
• W2946253525 cites W2114104545 @default.
• W2946253525 cites W2119784771 @default.
• W2946253525 cites W2126419817 @default.
• W2946253525 cites W2131271579 @default.
• W2946253525 cites W2137015675 @default.
• W2946253525 cites W2138581811 @default.
• W2946253525 cites W2142678478 @default.
• W2946253525 cites W2145803099 @default.
• W2946253525 cites W2149011343 @default.
• W2946253525 cites W2149463076 @default.
• W2946253525 cites W2153481411 @default.
• W2946253525 cites W2154834279 @default.
• W2946253525 cites W2157718208 @default.
• W2946253525 cites W2158217645 @default.
• W2946253525 cites W2158990581 @default.
• W2946253525 cites W2162098634 @default.
• W2946253525 cites W2164095252 @default.
• W2946253525 cites W2164154943 @default.
• W2946253525 cites W2167049138 @default.
• W2946253525 cites W2170551349 @default.
• W2946253525 cites W2170974037 @default.
• W2946253525 cites W2187650964 @default.
• W2946253525 cites W2311203695 @default.
• W2946253525 cites W2314199728 @default.
• W2946253525 cites W2401373346 @default.
• W2946253525 cites W2410496227 @default.
• W2946253525 cites W2467678998 @default.
• W2946253525 cites W2525666507 @default.
• W2946253525 cites W2592186402 @default.
• W2946253525 cites W2604831109 @default.
• W2946253525 cites W2613461946 @default.
• W2946253525 cites W2663640603 @default.
• W2946253525 cites W2888556703 @default.
• W2946253525 doi "https://doi.org/10.1371/journal.pone.0216982" @default.
• W2946253525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6522055" @default.
• W2946253525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31095623" @default.
• W2946253525 hasPublicationYear "2019" @default.

• next