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• W2946303419 abstract "Nanoplastics (NPs) spread widely with water and air current, and they can accumulate in aquatic organisms, even penetrating biofilms, which may cause persistent toxicity and potential hazards. This current study aimed to reveal the toxicological mechanism of different functionalized polystyrene (PS) NPs on Daphnia magna (D. magna) by investigating toxicity endpoints in individual level and biochemical level. In this study, acute toxicity, behavioral parameters and biomarker responses of D. magna was measured in the exposure of different functionalized PS NPs (plain PS, PS-p-NH2, PS-n-NH2 and PS-COOH). The results indicated that when exposed to the plain PS, ROS induction would activate MAPKs, thereby causing lethality and adverse behavior effects on D. magna; while the functionalized PS NPs were less toxic than the plain PS, especially for PS-p-NH2 which was severely flocculated after exposure, thus showing no immobilization at the investigated concentrations. Also, the antioxidant system was mainly stimulated due to the direct interaction with the cell surface receptor, which was different from the plain PS. Consequently, this work suggests significant effects of functional groups on NPs for environmental toxicity studies, and provides a better understanding of the toxicological mechanism on the toxicity of PS NPs toward D. magna." @default.
• W2946303419 created "2019-05-29" @default.
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• W2946303419 date "2019-09-01" @default.
• W2946303419 modified "2023-10-18" @default.
• W2946303419 title "Investigating the toxicities of different functionalized polystyrene nanoplastics on Daphnia magna" @default.
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• W2946303419 doi "https://doi.org/10.1016/j.ecoenv.2019.05.036" @default.
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