Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946363748> ?p ?o ?g. }
- W2946363748 endingPage "266" @default.
- W2946363748 startingPage "266" @default.
- W2946363748 abstract "Tryptophan (Trp) supplementation has been shown to improve growth performance and enhance intestinal integrity in piglets. However, the effects of dietary Trp supplementation on the intestinal barrier function in piglets exposed to oxidative stress remain unknown. This study was conducted to evaluate whether dietary Trp supplementation can attenuate intestinal injury, oxidative stress, and mitochondrial dysfunction of piglets caused by diquat injection. Thirty-two piglets at 25 days of age were randomly allocated to four groups: (1) the non-challenged control; (2) diquat-challenged control; (3) 0.15% Trp-supplemented diet + diquat; (4) 0.30% Trp supplemented diet + diquat. On day seven, the piglets were injected intraperitoneally with sterilized saline or diquat (10 mg/kg body weight). The experiment lasted 21 days. Dietary supplementation with 0.15% Trp improved growth performance of diquat-challenged piglets from day 7 to 21. Diquat induced an increased intestinal permeability, impaired antioxidant capacity, and mitochondrial dysfunction. Although dietary supplementation with 0.15% Trp ameliorated these negative effects induced by diquat challenge that showed decreasing permeability of 4 kDa fluorescein isothiocyanate dextran, increasing antioxidant indexes, and enhancing mitochondrial biogenesis. Results indicated that dietary supplementation with 0.15% Trp enhanced intestinal integrity, restored the redox status, and improved the mitochondrial function of piglets challenged with diquat." @default.
- W2946363748 created "2019-05-29" @default.
- W2946363748 creator A5015266968 @default.
- W2946363748 creator A5019493141 @default.
- W2946363748 creator A5041470064 @default.
- W2946363748 creator A5047350976 @default.
- W2946363748 creator A5079795759 @default.
- W2946363748 date "2019-05-22" @default.
- W2946363748 modified "2023-10-17" @default.
- W2946363748 title "L-Tryptophan Enhances Intestinal Integrity in Diquat-Challenged Piglets Associated with Improvement of Redox Status and Mitochondrial Function" @default.
- W2946363748 cites W1577653801 @default.
- W2946363748 cites W1787754175 @default.
- W2946363748 cites W1903344188 @default.
- W2946363748 cites W1967956234 @default.
- W2946363748 cites W1972851693 @default.
- W2946363748 cites W1975549936 @default.
- W2946363748 cites W1979842520 @default.
- W2946363748 cites W1987357375 @default.
- W2946363748 cites W2004956918 @default.
- W2946363748 cites W2026665386 @default.
- W2946363748 cites W2034698918 @default.
- W2946363748 cites W2042515284 @default.
- W2946363748 cites W2047317002 @default.
- W2946363748 cites W2050525037 @default.
- W2946363748 cites W2072165349 @default.
- W2946363748 cites W2078478545 @default.
- W2946363748 cites W2090798328 @default.
- W2946363748 cites W2094164338 @default.
- W2946363748 cites W2101861123 @default.
- W2946363748 cites W2101900191 @default.
- W2946363748 cites W2107249970 @default.
- W2946363748 cites W2113112289 @default.
- W2946363748 cites W2113347787 @default.
- W2946363748 cites W2125443686 @default.
- W2946363748 cites W2125640458 @default.
- W2946363748 cites W2130263296 @default.
- W2946363748 cites W2133065046 @default.
- W2946363748 cites W2135432388 @default.
- W2946363748 cites W2140853250 @default.
- W2946363748 cites W2157693087 @default.
- W2946363748 cites W2264779778 @default.
- W2946363748 cites W2328650856 @default.
- W2946363748 cites W2346053177 @default.
- W2946363748 cites W2411364350 @default.
- W2946363748 cites W2531606631 @default.
- W2946363748 cites W2580690889 @default.
- W2946363748 cites W2617937955 @default.
- W2946363748 cites W2623571756 @default.
- W2946363748 cites W2761457646 @default.
- W2946363748 cites W2792651356 @default.
- W2946363748 cites W2795511476 @default.
- W2946363748 cites W2807008103 @default.
- W2946363748 cites W2883853179 @default.
- W2946363748 cites W2884267073 @default.
- W2946363748 cites W2886189662 @default.
- W2946363748 cites W2904008200 @default.
- W2946363748 cites W2905138175 @default.
- W2946363748 cites W2911981367 @default.
- W2946363748 cites W2912271545 @default.
- W2946363748 cites W2912550132 @default.
- W2946363748 cites W2921840152 @default.
- W2946363748 cites W2937460528 @default.
- W2946363748 doi "https://doi.org/10.3390/ani9050266" @default.
- W2946363748 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6562546" @default.
- W2946363748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31121956" @default.
- W2946363748 hasPublicationYear "2019" @default.
- W2946363748 type Work @default.
- W2946363748 sameAs 2946363748 @default.
- W2946363748 citedByCount "37" @default.
- W2946363748 countsByYear W29463637482019 @default.
- W2946363748 countsByYear W29463637482020 @default.
- W2946363748 countsByYear W29463637482021 @default.
- W2946363748 countsByYear W29463637482022 @default.
- W2946363748 countsByYear W29463637482023 @default.
- W2946363748 crossrefType "journal-article" @default.
- W2946363748 hasAuthorship W2946363748A5015266968 @default.
- W2946363748 hasAuthorship W2946363748A5019493141 @default.
- W2946363748 hasAuthorship W2946363748A5041470064 @default.
- W2946363748 hasAuthorship W2946363748A5047350976 @default.
- W2946363748 hasAuthorship W2946363748A5079795759 @default.
- W2946363748 hasBestOaLocation W29463637481 @default.
- W2946363748 hasConcept C126322002 @default.
- W2946363748 hasConcept C134018914 @default.
- W2946363748 hasConcept C185592680 @default.
- W2946363748 hasConcept C2776151105 @default.
- W2946363748 hasConcept C2776527163 @default.
- W2946363748 hasConcept C2776706248 @default.
- W2946363748 hasConcept C2777163875 @default.
- W2946363748 hasConcept C2778004101 @default.
- W2946363748 hasConcept C2781071285 @default.
- W2946363748 hasConcept C515207424 @default.
- W2946363748 hasConcept C55493867 @default.
- W2946363748 hasConcept C71924100 @default.
- W2946363748 hasConcept C86803240 @default.
- W2946363748 hasConceptScore W2946363748C126322002 @default.
- W2946363748 hasConceptScore W2946363748C134018914 @default.
- W2946363748 hasConceptScore W2946363748C185592680 @default.
- W2946363748 hasConceptScore W2946363748C2776151105 @default.