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- W2946476104 abstract "Background and Aims To evaluate and compare intrathecalDexmedetomidine and intrathecal Clonidine as an adjuvant to 0.5% hyperbaric bupivacaine for lower limb surgeries, with respect to block characteristics, efficacy, haemodynamic changes&adverse effects. Materials and Methods: Ninety patients in the age group between 20 and 60 years of either sex belonging to ASA Grade I-II posted for elective lower limb surgeries were divided randomly into three groups ( n=30 ). Group B: received 15mg of 0.5% hyperbaricbupivacaine with 0.5ml normal saline. GroupC: received 15mg of 0.5% hyperbaricbupivacaine with 50µg Clonidine. GroupD: received 15mg of0.5% hyperbaric bupivacaine with 5µg Dexmedetomidine.The quality of block,total duration of analgesia,hemodynamic stability and side effects of the study drugs were recorded. Results : The mean time of onset of sensory blockade was shorter ingroup C (1.4±0.5mins) and group D (1.17±0.37mins) than group B (2.8 ± 0.66 mins). Two dermatomalregression time was longer in both Group C(136.33±10.9 mins)and D (136.33±10.9 mins)when compared to Group B(79.46±10.16mins).The mean duration of analgesia was 191±22.94mins, 342.33±28.12 mins and 369.33±34.13 mins in group B, group C and group D respectively. The mean time taken for the onset of motor blockade was 4.00±0.69mins, 1.63±0.49 mins and 1.13±0.346 mins in group B, group C and group D respectively. The mean time taken for attaining maximum motor blockade in Groups B,C & D was 6.57±0.93, 6.43±1.045 and 5.20±0.887mins. The mean duration of motor blockade was 166.16±20.95, 279±24.68 and 303.66±35.95 minsin group B, group C and group D respectively.The mean sedation score was 0.4±0.49 in group B, 0.50±0.682 in group C and 0.53±0.681 in group D. Conclusion IntrathecaldexmedetomidineOr intrathecal clonidine,when added as adjuvants with 15mg 0.5% hyperbaric bupivacainethey decrease the onset time,increase theduration of sensory &motor blockadeand provide good postoperative analgesia." @default.
- W2946476104 created "2019-05-29" @default.
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- W2946476104 date "2018-07-18" @default.
- W2946476104 modified "2023-09-23" @default.
- W2946476104 title "A COMPARATIVE STUDY OF INTRATHECAL DEXMEDETOMIDINE AND CLONIDINE AS AN ADJUVANT TO INTRATHECAL BUPIVACAINE IN ELECTIVE LOWER LIMB SURGERIES" @default.
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