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- W2946570072 abstract "Streptozotocin (STZ)-induced free radical oxidant activity resulted in muscle wasting due to protein carbonyl (PC), glucose transporter-4 (Glut-4), and interleukin-6 (IL-6) protein alteration. Antioxidant ingredient in the golden sea cucumber extract was found in promising level to inhibit free radical activity.This study was aimed to investigate the effect of golden sea cucumber extract on PC, IL-6, and Glut-4 level of STZ-induced diabetes mouse.This study was performed using mice, which were grouped into non-diabetes, diabetes, and diabetes-treated extract groups. The golden sea cucumber was extracted using 70% ethanol, which was administered by oral gavage twice a day for 5 consecutive days.The extract reduced PC level and improved muscle Glut-4 and IL-6 protein level of diabetic mouse.The extract of golden sea cucumber revived muscle Glut-4 and IL-6 protein level in protection against muscle wasting." @default.
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- W2946570072 date "2019-05-01" @default.
- W2946570072 modified "2023-10-12" @default.
- W2946570072 title "Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle" @default.
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- W2946570072 doi "https://doi.org/10.14202/vetworld.2019.684-688" @default.
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