FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946653650> ?p ?o ?g. }

• W2946653650 endingPage "8479" @default.
• W2946653650 startingPage "8472" @default.
• W2946653650 abstract "RNA G-quadruplexes are RNA secondary structures that are implicated in many cellular processes. Although conventional biophysical techniques are widely used for their in vitro characterization, more advanced methods are needed to study complex equilibria and the kinetics of their folding. We have developed a new Förster resonance energy-transfer-based method to detect the folding of RNA G-quadruplexes, which is enabled by labeling the 2'-positions of participating guanosines with fluorophores. Importantly, this does not interfere with the required anti conformation of the nucleobase in a quadruplex with parallel topology. Sequential click reactions on the solid phase and in solution using a stop-and-go strategy circumvented the issue of unselective cross-labeling. We exemplified the method on a series of sequences under different assay conditions. In contrast to the commonly used end-labeling approach, our internal labeling strategy would also allow the study of G-quadruplex formation in long functional RNAs." @default.
• W2946653650 created "2019-05-29" @default.
• W2946653650 creator A5004805033 @default.
• W2946653650 creator A5005744045 @default.
• W2946653650 creator A5012415692 @default.
• W2946653650 creator A5015813819 @default.
• W2946653650 creator A5023511822 @default.
• W2946653650 date "2019-05-14" @default.
• W2946653650 modified "2023-10-18" @default.
• W2946653650 title "Site-Specific Fluorophore Labeling of Guanosines in RNA G-Quadruplexes" @default.
• W2946653650 cites W1749812141 @default.
• W2946653650 cites W1966429309 @default.
• W2946653650 cites W1970574292 @default.
• W2946653650 cites W1973699439 @default.
• W2946653650 cites W1977279728 @default.
• W2946653650 cites W1981187936 @default.
• W2946653650 cites W1983407417 @default.
• W2946653650 cites W1990763521 @default.
• W2946653650 cites W1990864794 @default.
• W2946653650 cites W2005788509 @default.
• W2946653650 cites W2008225954 @default.
• W2946653650 cites W2009436485 @default.
• W2946653650 cites W2020710960 @default.
• W2946653650 cites W2022846880 @default.
• W2946653650 cites W2038929178 @default.
• W2946653650 cites W2045868610 @default.
• W2946653650 cites W2049001845 @default.
• W2946653650 cites W2055556773 @default.
• W2946653650 cites W2055557113 @default.
• W2946653650 cites W2065219073 @default.
• W2946653650 cites W2080450988 @default.
• W2946653650 cites W2088635998 @default.
• W2946653650 cites W2108763751 @default.
• W2946653650 cites W2108966130 @default.
• W2946653650 cites W2113996992 @default.
• W2946653650 cites W2114289148 @default.
• W2946653650 cites W2116166189 @default.
• W2946653650 cites W2116609429 @default.
• W2946653650 cites W2117559345 @default.
• W2946653650 cites W2128345861 @default.
• W2946653650 cites W2132480368 @default.
• W2946653650 cites W2142080511 @default.
• W2946653650 cites W2144477021 @default.
• W2946653650 cites W2150409129 @default.
• W2946653650 cites W2155773930 @default.
• W2946653650 cites W2157534860 @default.
• W2946653650 cites W2163533539 @default.
• W2946653650 cites W2164679923 @default.
• W2946653650 cites W2165072963 @default.
• W2946653650 cites W2167086055 @default.
• W2946653650 cites W2168335282 @default.
• W2946653650 cites W2171830519 @default.
• W2946653650 cites W2181976524 @default.
• W2946653650 cites W2200350721 @default.
• W2946653650 cites W2263306864 @default.
• W2946653650 cites W2335183043 @default.
• W2946653650 cites W2469100205 @default.
• W2946653650 cites W2509153611 @default.
• W2946653650 cites W2509744494 @default.
• W2946653650 cites W2511046608 @default.
• W2946653650 cites W2518087534 @default.
• W2946653650 cites W2547929719 @default.
• W2946653650 cites W2583803746 @default.
• W2946653650 cites W2598834336 @default.
• W2946653650 cites W2622100496 @default.
• W2946653650 cites W2887651904 @default.
• W2946653650 doi "https://doi.org/10.1021/acsomega.9b00704" @default.
• W2946653650 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6648711" @default.
• W2946653650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31459936" @default.
• W2946653650 hasPublicationYear "2019" @default.
• W2946653650 type Work @default.
• W2946653650 sameAs 2946653650 @default.
• W2946653650 citedByCount "4" @default.
• W2946653650 countsByYear W29466536502021 @default.
• W2946653650 crossrefType "journal-article" @default.
• W2946653650 hasAuthorship W2946653650A5004805033 @default.
• W2946653650 hasAuthorship W2946653650A5005744045 @default.
• W2946653650 hasAuthorship W2946653650A5012415692 @default.
• W2946653650 hasAuthorship W2946653650A5015813819 @default.
• W2946653650 hasAuthorship W2946653650A5023511822 @default.
• W2946653650 hasBestOaLocation W29466536501 @default.
• W2946653650 hasConcept C104317684 @default.
• W2946653650 hasConcept C119599485 @default.
• W2946653650 hasConcept C121332964 @default.
• W2946653650 hasConcept C12554922 @default.
• W2946653650 hasConcept C126142528 @default.
• W2946653650 hasConcept C127413603 @default.
• W2946653650 hasConcept C185592680 @default.
• W2946653650 hasConcept C21951064 @default.
• W2946653650 hasConcept C2776545253 @default.
• W2946653650 hasConcept C2777995097 @default.
• W2946653650 hasConcept C2778617687 @default.
• W2946653650 hasConcept C552990157 @default.
• W2946653650 hasConcept C55493867 @default.
• W2946653650 hasConcept C62520636 @default.
• W2946653650 hasConcept C67705224 @default.
• W2946653650 hasConcept C69610077 @default.
• W2946653650 hasConcept C70721500 @default.

• next