Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946691489> ?p ?o ?g. }
- W2946691489 abstract "Abstract Regeneration of a limb or tissue can be achieved through multiple different pathways and mechanisms. The sea anemone Exaiptasia pallida has been observed to have excellent regenerative proficiency but this has not yet been described transcriptionally. In this study we examined the genetic expression changes during a regenerative timecourse and report key genes involved in regeneration and wound healing. We found that the major response was an early upregulation of genes involved in cellular movement and cell communication, which likely contribute to a high level of tissue plasticity resulting in the rapid regeneration response observed in this species. We find the immune system is only transcriptionally active in the first eight hours post-amputation and conclude, in accordance with previous literature, that the immune system and regeneration have an inverse relationship. Fifty-nine genes (3.8% of total) differentially expressed during regeneration were identified as having no orthologues in other species, indicating that regeneration in E. pallida may rely on the activation of species-specific novel genes. Additionally, taxonomically-restricted novel genes, including species-specific novels, and highly conserved genes were identified throughout the regenerative timecourse, showing that both may work in concert to achieve complete regeneration. We conclude that E. pallida behaves similarly to other anemone species such as Nematostella vectensis and Calliactis polypus but with some notable novel differences." @default.
- W2946691489 created "2019-05-29" @default.
- W2946691489 creator A5003562114 @default.
- W2946691489 creator A5016722071 @default.
- W2946691489 creator A5019500357 @default.
- W2946691489 creator A5055370710 @default.
- W2946691489 creator A5066915750 @default.
- W2946691489 creator A5069576740 @default.
- W2946691489 creator A5082470071 @default.
- W2946691489 date "2019-05-24" @default.
- W2946691489 modified "2023-10-16" @default.
- W2946691489 title "The rapid regenerative response of a model sea anemone speciesExaiptasia pallidais characterised by tissue plasticity and highly coordinated cell communication" @default.
- W2946691489 cites W1537776120 @default.
- W2946691489 cites W1655970319 @default.
- W2946691489 cites W1784854092 @default.
- W2946691489 cites W1798321344 @default.
- W2946691489 cites W1961438741 @default.
- W2946691489 cites W1965893268 @default.
- W2946691489 cites W1974765744 @default.
- W2946691489 cites W1976785417 @default.
- W2946691489 cites W1977046333 @default.
- W2946691489 cites W1977859262 @default.
- W2946691489 cites W1986492978 @default.
- W2946691489 cites W2000783260 @default.
- W2946691489 cites W2009641761 @default.
- W2946691489 cites W2011657487 @default.
- W2946691489 cites W2011979100 @default.
- W2946691489 cites W2016854872 @default.
- W2946691489 cites W2018938817 @default.
- W2946691489 cites W2026345779 @default.
- W2946691489 cites W2041612616 @default.
- W2946691489 cites W2042263379 @default.
- W2946691489 cites W2047348172 @default.
- W2946691489 cites W2049201889 @default.
- W2946691489 cites W2050907074 @default.
- W2946691489 cites W2067558229 @default.
- W2946691489 cites W2069235384 @default.
- W2946691489 cites W2075127796 @default.
- W2946691489 cites W2082156898 @default.
- W2946691489 cites W2085293124 @default.
- W2946691489 cites W2094629012 @default.
- W2946691489 cites W2102006804 @default.
- W2946691489 cites W2106637900 @default.
- W2946691489 cites W2110201610 @default.
- W2946691489 cites W2113188354 @default.
- W2946691489 cites W2121150700 @default.
- W2946691489 cites W2128571613 @default.
- W2946691489 cites W2131271579 @default.
- W2946691489 cites W2131296612 @default.
- W2946691489 cites W2132120234 @default.
- W2946691489 cites W2137342974 @default.
- W2946691489 cites W2145396058 @default.
- W2946691489 cites W2146590332 @default.
- W2946691489 cites W2148904430 @default.
- W2946691489 cites W2158797557 @default.
- W2946691489 cites W2171130969 @default.
- W2946691489 cites W2172157220 @default.
- W2946691489 cites W2182363306 @default.
- W2946691489 cites W2207583920 @default.
- W2946691489 cites W2319893584 @default.
- W2946691489 cites W2339355968 @default.
- W2946691489 cites W2395058975 @default.
- W2946691489 cites W2407844261 @default.
- W2946691489 cites W2410711292 @default.
- W2946691489 cites W2435882090 @default.
- W2946691489 cites W2511464995 @default.
- W2946691489 cites W2528601009 @default.
- W2946691489 cites W2548416339 @default.
- W2946691489 cites W2563838222 @default.
- W2946691489 cites W2585475127 @default.
- W2946691489 cites W2589060305 @default.
- W2946691489 cites W2605702145 @default.
- W2946691489 cites W2736604551 @default.
- W2946691489 cites W2780462723 @default.
- W2946691489 cites W2781884266 @default.
- W2946691489 cites W2797456644 @default.
- W2946691489 cites W2924807738 @default.
- W2946691489 cites W2954142712 @default.
- W2946691489 cites W4241343264 @default.
- W2946691489 cites W589248068 @default.
- W2946691489 doi "https://doi.org/10.1101/644732" @default.
- W2946691489 hasPublicationYear "2019" @default.
- W2946691489 type Work @default.
- W2946691489 sameAs 2946691489 @default.
- W2946691489 citedByCount "1" @default.
- W2946691489 countsByYear W29466914892022 @default.
- W2946691489 crossrefType "posted-content" @default.
- W2946691489 hasAuthorship W2946691489A5003562114 @default.
- W2946691489 hasAuthorship W2946691489A5016722071 @default.
- W2946691489 hasAuthorship W2946691489A5019500357 @default.
- W2946691489 hasAuthorship W2946691489A5055370710 @default.
- W2946691489 hasAuthorship W2946691489A5066915750 @default.
- W2946691489 hasAuthorship W2946691489A5069576740 @default.
- W2946691489 hasAuthorship W2946691489A5082470071 @default.
- W2946691489 hasBestOaLocation W29466914891 @default.
- W2946691489 hasConcept C104317684 @default.
- W2946691489 hasConcept C171056886 @default.
- W2946691489 hasConcept C54355233 @default.
- W2946691489 hasConcept C86803240 @default.
- W2946691489 hasConcept C95444343 @default.