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• W2946743318 abstract "The discovery, design and synthesis of a new series of GSMs is described. The classical imidazole heterocycle has been replaced by a cyano group attached to an indole nucleus. The exploration of this series has led to compound 26-S which combined high in vitro and in vivo potency with an acceptable drug-like profile." @default.
• W2946743318 created "2019-05-29" @default.
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• W2946743318 date "2019-07-01" @default.
• W2946743318 modified "2023-09-26" @default.
• W2946743318 title "Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators" @default.
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• W2946743318 doi "https://doi.org/10.1016/j.bmcl.2019.05.023" @default.
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