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- W2946850022 abstract "The sulfated α-l-fucans ScF and LlF were obtained from brown algae of the Laminariaceae family (Saccharina cichorioides and Laminaria longipes). According to spectroscopy NMR, the LlF fucan predominantly contained the →3)-α-l-Fucp-(2SO3–)-(1→4)-α-l-Fucp-(1→2)-α-l-Fucp-(4SO3–)-(1→ repeating units, with small amounts of disaccharide 1,4-linked fragments and 3-sulfated fucose residues. Mass spectrometric analysis revealed the presence of the following fragments in the fucan structure: α-l-Fucp-(2SO3–)-(1→4)-α-l-Fucp-(2SO3–)-(1→3)-α-l-Fucp-(4SO3–); α-l-Fucp-(2,4SO3–)-(1→3)-α-l-Fucp-(1→3)-α-l-Fucp-(4SO3–); α-l-Fucp-(2SO3–)-(1→2)-α-l-Fucp; α-l-Fucp-(2SO3–)-(1→2)-α-l-Fucp-(4SO3–); α-l-Fucp-(2SO3–)-(1→3)-α-l-Fucp; α-l-Fucp-(2,4SO3–)-(1→3)-α-l-Fucp; α-l-Fucp-(4SO3–)-(1→4)-α-l-Fucp; and α-l-Fucp-(4SO3–)-(1→4)-α-l-Fucp-(2SO3–). Both ScF and LlF fucoidans inhibited colony formation and growth of melanoma and colon cancer cells and sensitize-tested cancer cells to X-ray radiation to a comparable degree." @default.
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- W2946850022 date "2019-10-01" @default.
- W2946850022 modified "2023-10-16" @default.
- W2946850022 title "Fucoidans from brown algae Laminaria longipes and Saccharina cichorioides: Structural characteristics, anticancer and radiosensitizing activity in vitro" @default.
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- W2946850022 doi "https://doi.org/10.1016/j.carbpol.2019.05.079" @default.
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