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- W2946897536 abstract "Abstract Herein we demonstrate a chemoselective reaction of N β ‐protected amino alkyl sulfonyl azides with in situ generated N α ‐protected amino acid selenocarboxylates via step wise intramolecular cyclization followed by decomposition to obtain N‐acyl sulfonamide tethered peptidyl conjugates. The protocol offers the synthesis of orthogonally protected N‐acyl sulfonamide tethered peptidomimetics under simple and mild reaction conditions employing commercially available amino acids in presence of NaBH 2 Se 3 as a selenating agent. Also, the synthesis of N‐acyl sulfonamide tethered amino acid and aryl conjugates were accomplished as an extension of the above strategy." @default.
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- W2946897536 date "2019-05-31" @default.
- W2946897536 modified "2023-10-16" @default.
- W2946897536 title "A Unified Approach to Access <i>N</i> ‐Acyl Sulfonamide Tethered Peptide Conjugates" @default.
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- W2946897536 doi "https://doi.org/10.1002/slct.201901024" @default.
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