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- W2946965802 abstract "Hybrid nanomaterials with inherent physicochemical properties and cytocompatibility are beneficial for healthcare utilities. This paper demonstrates the hybridization of transition-metal oxide (molybdenum trioxide, MoO3), optoelectrochemically active dye complex (Ru(II)), and biopolymer (chitosan, CS) into a single nanosystem. The asafetida-resin-mediated green synthesis of MoO3 nanoparticles (g-MoO3 NPs) enabled chemical adsorption of Ru(II) and CS. Optical imaging functionality of pristine g-MoO3, g-MoO3-Ru(II), and g-MoO3-Ru(II)/CS has been evaluated using Caenorhabditis elegans, as an in vivo animal model, at an excitation wavelength of 450 nm and observed emission of ∼600 nm. The localization of chitosan on the surface of g-MoO3-Ru(II) exhibits cytocompatibility promising for intracellular imaging. The intracellular antioxidant properties of the g-MoO3-Ru(II)/CS nanocomposite are more profound than pristine NPs as assessed by measuring reactive oxygen species and protein carbonyls against the standard drug resveratrol. The electrochemical transducing ability of the hybrid g-MoO3-Ru(II) nanocomposite has been tested using butein, as a model herbaceutical, with nanomolar precision (50-1250 nM). The triad composite of metal oxide, dye, and biopolymer enabled synergistic properties that are suitable for multifunctional application in intracellular imaging, antioxidant, and electrochemical sensor studies." @default.
- W2946965802 created "2019-06-07" @default.
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- W2946965802 date "2019-05-30" @default.
- W2946965802 modified "2023-09-26" @default.
- W2946965802 title "Chitosanylated MoO<sub>3</sub>–Ruthenium(II) Nanocomposite as Biocompatible Probe for Bioimaging and Herbaceutical Detection" @default.
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- W2946965802 doi "https://doi.org/10.1021/acsbiomaterials.9b00575" @default.
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