FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946985296> ?p ?o ?g. }

• W2946985296 abstract "Abstract In South East Asia, dengue epidemics have increased in size and geographical distribution in recent years. Most studies investigating dengue transmission and control have had an urban focus, while less consideration is currently given to rural settings, or where urban and rural areas overlap. We examined the spatiotemporal distribution and epidemiological characteristics of reported dengue cases in the predominantly rural state of Sabah, in Malaysian Borneo – an area where sylvatic and urban circulation of pathogens are known to intersect. We found that annual dengue incidence rates were spatially variable over the 7-year study period from 2010-2016 (state-wide mean annual incidence of 21 cases/100,000 people; range 5-42/100,000), but were highest in rural localities in the western districts of the state (Kuala Penyu, Nabawan, Tenom and Kota Marudu). The eastern districts exhibited lower overall dengue rates; however, we noted a concentration of severe (haemorrhagic) dengue cases (44%) in Sandakan and Tawau districts. Dengue incidence was slightly higher for males than females, and was significantly higher for both genders aged between 10 and 29 years (24/100,000; p=0.029). The largest ever recorded outbreaks occurred during 2015-2016, with the vector Aedes albopictus found to be most prevalent in both urban and rural households (House Index of 64%), compared with Ae. Aegypti (15%). These findings suggest that dengue outbreaks in Sabah are driven by the sporadic expansion of dengue virus in both urban and rural settings. This may require tailoring of preventative strategies to suit different transmission ecologies across Sabah. Further studies to better understand the drivers of dengue in Sabah may aid dengue control efforts in Malaysia, and more broadly in South East Asia. Author summary In order to combat the rising regional incidence of dengue in South East Asia, the drivers of transmission must be better characterised across different environmental settings. We conducted the first retrospective analysis of dengue epidemiology in the predominantly rural state of Sabah, Malaysia, where both urban and sylvatic transmission cycles exist. Human notification data over a 7-year period were reviewed and spatiotemporal and demographic risk factors identified. We found: Urban habitats and population density are not the only determinants mediating the spread of epidemic dengue in Sabah. Case from both urban and rural localities contributed equally to dengue outbreaks. Human demographic risk factors included being aged between 10 and 29 years, and being male. High incidence areas for dengue do not predict the occurrence of severe dengue. Severe dengue was largely localised to lower incidence districts in the east of the state. The sole presence of Aedes albopictus in and around the majority of urban and rural case households suggests that this vector may play a major role in facilitating outbreaks. A complex interplay of risk factors likely mediates dengue transmission in Sabah, influenced by both regional climate trends and localised human and ecological influences. This study emphasises that the increasing spread of dengue in urban South East Asia is also mirrored in more rural areas, and suggests a need for control strategies that address both urban and rural dengue risk." @default.
• W2946985296 created "2019-06-07" @default.
• W2946985296 creator A5000919704 @default.
• W2946985296 creator A5011084530 @default.
• W2946985296 creator A5030637522 @default.
• W2946985296 creator A5031702630 @default.
• W2946985296 creator A5038783239 @default.
• W2946985296 creator A5045549244 @default.
• W2946985296 creator A5048756097 @default.
• W2946985296 creator A5049595024 @default.
• W2946985296 creator A5073741538 @default.
• W2946985296 date "2019-05-31" @default.
• W2946985296 modified "2023-09-23" @default.
• W2946985296 title "Spatial and epidemiologic features of dengue in Sabah, Malaysia" @default.
• W2946985296 cites W1506558804 @default.
• W2946985296 cites W1612962545 @default.
• W2946985296 cites W1968715864 @default.
• W2946985296 cites W1971914922 @default.
• W2946985296 cites W1974553284 @default.
• W2946985296 cites W1981407198 @default.
• W2946985296 cites W1983290796 @default.
• W2946985296 cites W1989236722 @default.
• W2946985296 cites W1991501606 @default.
• W2946985296 cites W1996883424 @default.
• W2946985296 cites W2004106419 @default.
• W2946985296 cites W2022668283 @default.
• W2946985296 cites W2025675035 @default.
• W2946985296 cites W2034050258 @default.
• W2946985296 cites W2037657217 @default.
• W2946985296 cites W2038675620 @default.
• W2946985296 cites W2042525870 @default.
• W2946985296 cites W2056298081 @default.
• W2946985296 cites W2057172276 @default.
• W2946985296 cites W2057676857 @default.
• W2946985296 cites W2057982504 @default.
• W2946985296 cites W2060984136 @default.
• W2946985296 cites W2066938684 @default.
• W2946985296 cites W2074607858 @default.
• W2946985296 cites W2083614812 @default.
• W2946985296 cites W2083882481 @default.
• W2946985296 cites W2093662995 @default.
• W2946985296 cites W2094308653 @default.
• W2946985296 cites W2096551676 @default.
• W2946985296 cites W2101113405 @default.
• W2946985296 cites W2111912125 @default.
• W2946985296 cites W2118378861 @default.
• W2946985296 cites W2124960416 @default.
• W2946985296 cites W2131222241 @default.
• W2946985296 cites W2150649949 @default.
• W2946985296 cites W2154808693 @default.
• W2946985296 cites W2156203827 @default.
• W2946985296 cites W2159856735 @default.
• W2946985296 cites W2165410465 @default.
• W2946985296 cites W2228451282 @default.
• W2946985296 cites W2512428562 @default.
• W2946985296 cites W2528546111 @default.
• W2946985296 cites W2543484671 @default.
• W2946985296 cites W2587989762 @default.
• W2946985296 cites W2588324513 @default.
• W2946985296 cites W2591685082 @default.
• W2946985296 cites W2726091384 @default.
• W2946985296 cites W2730619833 @default.
• W2946985296 cites W2753458334 @default.
• W2946985296 cites W2771036427 @default.
• W2946985296 cites W2779454305 @default.
• W2946985296 cites W2784239453 @default.
• W2946985296 cites W2789410922 @default.
• W2946985296 cites W2789494329 @default.
• W2946985296 cites W2808230658 @default.
• W2946985296 cites W2895495762 @default.
• W2946985296 cites W2924401596 @default.
• W2946985296 cites W4232620851 @default.
• W2946985296 doi "https://doi.org/10.1101/657031" @default.
• W2946985296 hasPublicationYear "2019" @default.
• W2946985296 type Work @default.
• W2946985296 sameAs 2946985296 @default.
• W2946985296 citedByCount "3" @default.
• W2946985296 countsByYear W29469852962020 @default.
• W2946985296 countsByYear W29469852962021 @default.
• W2946985296 countsByYear W29469852962022 @default.
• W2946985296 crossrefType "posted-content" @default.
• W2946985296 hasAuthorship W2946985296A5000919704 @default.
• W2946985296 hasAuthorship W2946985296A5011084530 @default.
• W2946985296 hasAuthorship W2946985296A5030637522 @default.
• W2946985296 hasAuthorship W2946985296A5031702630 @default.
• W2946985296 hasAuthorship W2946985296A5038783239 @default.
• W2946985296 hasAuthorship W2946985296A5045549244 @default.
• W2946985296 hasAuthorship W2946985296A5048756097 @default.
• W2946985296 hasAuthorship W2946985296A5049595024 @default.
• W2946985296 hasAuthorship W2946985296A5073741538 @default.
• W2946985296 hasBestOaLocation W29469852961 @default.
• W2946985296 hasConcept C104317684 @default.
• W2946985296 hasConcept C107130276 @default.
• W2946985296 hasConcept C110121322 @default.
• W2946985296 hasConcept C116675565 @default.
• W2946985296 hasConcept C119599485 @default.
• W2946985296 hasConcept C120665830 @default.
• W2946985296 hasConcept C121332964 @default.
• W2946985296 hasConcept C126322002 @default.
• W2946985296 hasConcept C127413603 @default.

• next