FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2946987005> ?p ?o ?g. }

• W2946987005 endingPage "210" @default.
• W2946987005 startingPage "210" @default.
• W2946987005 abstract "Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, has been shown to influence breast cancer susceptibility. The relationship between its risk of breast cancer and IL-1β-C31T polymorphism has been demonstrated, but the results remain controversial. Therefore, our study aimed to investigate the correlation between the IL-1β-C31T gene polymorphism and susceptibility to breast cancer.The genotype frequencies of IL-1β-C31T polymorphism were compared between 204 breast cancer cases and 210 controls using polymerase chain reaction and restriction fragment length polymorphism techinques. Further multivariate binary logistic regression analyses were used to assess the association between IL-1β-C31T polymorphism and breast cancer risk.The frequency of the T allele of IL-1β-C31T polymorphism in breast cancer cases was significantly higher than that in the controls (56.1% vs. 47.9%). The frequencies of genotypes CC, CT, and TT in the cases were 22.1%, 43.6%, and 34.3%, respectively, while in the control group they were 24.3%, 55.7%, and 20.0%, respectively. There was a significant difference between the prevalence of TT genotype in the 2 groups (adjusted odds ratio [OR], 2.06; 95% confidence interval [CI], 1.16-3.66; p = 0.014). Breast cancer risk increased in women with TT genotype, body mass index (BMI) ≥ 25 kg/m2 (OR, 2.19; 95% CI, 1.09-4.36), late age at first birth (OR, 2.43; 95% CI, 1.29-4.56), postmenopausal status (OR, 3.15; 95% CI, 1.39-7.16), and negative smoking history (OR, 2.52; 95% CI, 1.32-4.82). Furthermore, increase in breast cancer risk among women diagnosed with invasive ductal carcinoma was associated with CT/TT genotypes (OR, 2.82; 95% CI, 1.38-5.76).The IL-1β-C31T polymorphism affects breast cancer susceptibility, especially in women with late age at first birth, high BMI, postmenopausal status, negative smoking history, and invasive ductal carcinoma. Our study adds to the evidence about the importance of IL-1β-C31T polymorphism in breast cancer susceptibility." @default.
• W2946987005 created "2019-06-07" @default.
• W2946987005 creator A5005598025 @default.
• W2946987005 creator A5011832531 @default.
• W2946987005 creator A5033957239 @default.
• W2946987005 creator A5067481235 @default.
• W2946987005 creator A5069553300 @default.
• W2946987005 date "2019-01-01" @default.
• W2946987005 modified "2023-10-03" @default.
• W2946987005 title "The Correlation between<i>IL-1β-C31T</i>Gene Polymorphism and Susceptibility to Breast Cancer" @default.
• W2946987005 cites W1507614029 @default.
• W2946987005 cites W1518308640 @default.
• W2946987005 cites W1576756779 @default.
• W2946987005 cites W1851243786 @default.
• W2946987005 cites W1980286720 @default.
• W2946987005 cites W1983182914 @default.
• W2946987005 cites W1984752955 @default.
• W2946987005 cites W1997861947 @default.
• W2946987005 cites W2007355771 @default.
• W2946987005 cites W2010112824 @default.
• W2946987005 cites W2021224960 @default.
• W2946987005 cites W2024652143 @default.
• W2946987005 cites W2049102122 @default.
• W2946987005 cites W2064114517 @default.
• W2946987005 cites W2067263364 @default.
• W2946987005 cites W2079110325 @default.
• W2946987005 cites W2095020046 @default.
• W2946987005 cites W2096715492 @default.
• W2946987005 cites W2104313207 @default.
• W2946987005 cites W2145850340 @default.
• W2946987005 cites W2145866317 @default.
• W2946987005 cites W2332912393 @default.
• W2946987005 cites W2334630383 @default.
• W2946987005 cites W2398492668 @default.
• W2946987005 cites W2419077917 @default.
• W2946987005 cites W2617069367 @default.
• W2946987005 cites W2728180774 @default.
• W2946987005 cites W2755102894 @default.
• W2946987005 cites W2783929470 @default.
• W2946987005 cites W2803101639 @default.
• W2946987005 doi "https://doi.org/10.4048/jbc.2019.22.e27" @default.
• W2946987005 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6597413" @default.
• W2946987005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31281724" @default.
• W2946987005 hasPublicationYear "2019" @default.
• W2946987005 type Work @default.
• W2946987005 sameAs 2946987005 @default.
• W2946987005 citedByCount "11" @default.
• W2946987005 countsByYear W29469870052019 @default.
• W2946987005 countsByYear W29469870052020 @default.
• W2946987005 countsByYear W29469870052021 @default.
• W2946987005 countsByYear W29469870052022 @default.
• W2946987005 countsByYear W29469870052023 @default.
• W2946987005 crossrefType "journal-article" @default.
• W2946987005 hasAuthorship W2946987005A5005598025 @default.
• W2946987005 hasAuthorship W2946987005A5011832531 @default.
• W2946987005 hasAuthorship W2946987005A5033957239 @default.
• W2946987005 hasAuthorship W2946987005A5067481235 @default.
• W2946987005 hasAuthorship W2946987005A5069553300 @default.
• W2946987005 hasBestOaLocation W29469870051 @default.
• W2946987005 hasConcept C104317684 @default.
• W2946987005 hasConcept C121608353 @default.
• W2946987005 hasConcept C126322002 @default.
• W2946987005 hasConcept C135763542 @default.
• W2946987005 hasConcept C143998085 @default.
• W2946987005 hasConcept C151956035 @default.
• W2946987005 hasConcept C156957248 @default.
• W2946987005 hasConcept C2780221984 @default.
• W2946987005 hasConcept C29456083 @default.
• W2946987005 hasConcept C44249647 @default.
• W2946987005 hasConcept C530470458 @default.
• W2946987005 hasConcept C54355233 @default.
• W2946987005 hasConcept C71924100 @default.
• W2946987005 hasConcept C86803240 @default.
• W2946987005 hasConcept C90924648 @default.
• W2946987005 hasConceptScore W2946987005C104317684 @default.
• W2946987005 hasConceptScore W2946987005C121608353 @default.
• W2946987005 hasConceptScore W2946987005C126322002 @default.
• W2946987005 hasConceptScore W2946987005C135763542 @default.
• W2946987005 hasConceptScore W2946987005C143998085 @default.
• W2946987005 hasConceptScore W2946987005C151956035 @default.
• W2946987005 hasConceptScore W2946987005C156957248 @default.
• W2946987005 hasConceptScore W2946987005C2780221984 @default.
• W2946987005 hasConceptScore W2946987005C29456083 @default.
• W2946987005 hasConceptScore W2946987005C44249647 @default.
• W2946987005 hasConceptScore W2946987005C530470458 @default.
• W2946987005 hasConceptScore W2946987005C54355233 @default.
• W2946987005 hasConceptScore W2946987005C71924100 @default.
• W2946987005 hasConceptScore W2946987005C86803240 @default.
• W2946987005 hasConceptScore W2946987005C90924648 @default.
• W2946987005 hasIssue "2" @default.
• W2946987005 hasLocation W29469870051 @default.
• W2946987005 hasLocation W29469870052 @default.
• W2946987005 hasLocation W29469870053 @default.
• W2946987005 hasLocation W29469870054 @default.
• W2946987005 hasOpenAccess W2946987005 @default.
• W2946987005 hasPrimaryLocation W29469870051 @default.
• W2946987005 hasRelatedWork W1996753309 @default.
• W2946987005 hasRelatedWork W2037611947 @default.

• next