Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947038811> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2947038811 abstract "Background This study investigated SOCS1 box expression in mechanically strained ventricular myocardium in culture transfection preparations. Methods The left ventricle anterior wall strip in mice was mechanically loaded by length stretching during tissue culture. While constructing the SOCS1 vector, intransfection preparations were also carried out. The preparations of mechanically strained cultures continued for 72 hours. After total proteins were extracted, SDS-PAGE assay was used for evaluating 25 kDa band optical density in the cultured preparations. SOCS1box specific expression optical density was calculated in western blot transfer membrane. Results The total proteins in 25 kDa band were highly expressed in transfection preparations; however, mechanical strain induced increased 25 kDa expression but not significantly. SCOS1 box protein was significantly increased in strained but not in transfection preparations. Furthermore, SCOS1 box expression occurred in the precipitate rather than in the supernatant of strain cultured preparations. Conclusion SOCS1 box protein is mechanically strained cellular signaling which is expressed in mechanically strained cultured mice ventricular myocardium. Transfection alone does not make a significant expression in this model, but combination with mechanical straining can dramatically increase nuclear SOCS1 box protein in cultured ventricular myocardium. Acknowledgements Supported by project grant from Hainan Medical College Undergraduate Training Programs for Innovation and Entrepreneurship (HYCX2018068), Hainan Key Research and Development project (ZDYF2017121)." @default.
- W2947038811 created "2019-06-07" @default.
- W2947038811 creator A5002476310 @default.
- W2947038811 creator A5013962906 @default.
- W2947038811 creator A5021247073 @default.
- W2947038811 creator A5037882846 @default.
- W2947038811 creator A5037951973 @default.
- W2947038811 creator A5050884691 @default.
- W2947038811 creator A5058565575 @default.
- W2947038811 creator A5059948736 @default.
- W2947038811 creator A5064858378 @default.
- W2947038811 creator A5069171624 @default.
- W2947038811 creator A5070001876 @default.
- W2947038811 creator A5089693961 @default.
- W2947038811 date "2019-03-01" @default.
- W2947038811 modified "2023-09-27" @default.
- W2947038811 title "16 SOCS1 box evoked expression in mechanically strained cultured mice ventricle myocardium" @default.
- W2947038811 doi "https://doi.org/10.1136/jim-2019-000994.16" @default.
- W2947038811 hasPublicationYear "2019" @default.
- W2947038811 type Work @default.
- W2947038811 sameAs 2947038811 @default.
- W2947038811 citedByCount "0" @default.
- W2947038811 crossrefType "proceedings-article" @default.
- W2947038811 hasAuthorship W2947038811A5002476310 @default.
- W2947038811 hasAuthorship W2947038811A5013962906 @default.
- W2947038811 hasAuthorship W2947038811A5021247073 @default.
- W2947038811 hasAuthorship W2947038811A5037882846 @default.
- W2947038811 hasAuthorship W2947038811A5037951973 @default.
- W2947038811 hasAuthorship W2947038811A5050884691 @default.
- W2947038811 hasAuthorship W2947038811A5058565575 @default.
- W2947038811 hasAuthorship W2947038811A5059948736 @default.
- W2947038811 hasAuthorship W2947038811A5064858378 @default.
- W2947038811 hasAuthorship W2947038811A5069171624 @default.
- W2947038811 hasAuthorship W2947038811A5070001876 @default.
- W2947038811 hasAuthorship W2947038811A5089693961 @default.
- W2947038811 hasConcept C104317684 @default.
- W2947038811 hasConcept C105702510 @default.
- W2947038811 hasConcept C126322002 @default.
- W2947038811 hasConcept C150194340 @default.
- W2947038811 hasConcept C153911025 @default.
- W2947038811 hasConcept C16685009 @default.
- W2947038811 hasConcept C185592680 @default.
- W2947038811 hasConcept C2776415932 @default.
- W2947038811 hasConcept C2778022156 @default.
- W2947038811 hasConcept C2778921608 @default.
- W2947038811 hasConcept C54009773 @default.
- W2947038811 hasConcept C55493867 @default.
- W2947038811 hasConcept C6856738 @default.
- W2947038811 hasConcept C71924100 @default.
- W2947038811 hasConcept C86803240 @default.
- W2947038811 hasConcept C95444343 @default.
- W2947038811 hasConceptScore W2947038811C104317684 @default.
- W2947038811 hasConceptScore W2947038811C105702510 @default.
- W2947038811 hasConceptScore W2947038811C126322002 @default.
- W2947038811 hasConceptScore W2947038811C150194340 @default.
- W2947038811 hasConceptScore W2947038811C153911025 @default.
- W2947038811 hasConceptScore W2947038811C16685009 @default.
- W2947038811 hasConceptScore W2947038811C185592680 @default.
- W2947038811 hasConceptScore W2947038811C2776415932 @default.
- W2947038811 hasConceptScore W2947038811C2778022156 @default.
- W2947038811 hasConceptScore W2947038811C2778921608 @default.
- W2947038811 hasConceptScore W2947038811C54009773 @default.
- W2947038811 hasConceptScore W2947038811C55493867 @default.
- W2947038811 hasConceptScore W2947038811C6856738 @default.
- W2947038811 hasConceptScore W2947038811C71924100 @default.
- W2947038811 hasConceptScore W2947038811C86803240 @default.
- W2947038811 hasConceptScore W2947038811C95444343 @default.
- W2947038811 hasLocation W29470388111 @default.
- W2947038811 hasOpenAccess W2947038811 @default.
- W2947038811 hasPrimaryLocation W29470388111 @default.
- W2947038811 hasRelatedWork W1981607035 @default.
- W2947038811 hasRelatedWork W2017159555 @default.
- W2947038811 hasRelatedWork W2044860379 @default.
- W2947038811 hasRelatedWork W2135608215 @default.
- W2947038811 hasRelatedWork W2385819341 @default.
- W2947038811 hasRelatedWork W3029694811 @default.
- W2947038811 isParatext "false" @default.
- W2947038811 isRetracted "false" @default.
- W2947038811 magId "2947038811" @default.
- W2947038811 workType "article" @default.