Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947087777> ?p ?o ?g. }
- W2947087777 endingPage "5" @default.
- W2947087777 startingPage "1" @default.
- W2947087777 abstract "There is a recent growing evidence that abnormalities in the microbiota composition can have a major role in the development of obesity and diabetes and that some actions of metformin may be mediated by gut bacteria. Several mechanisms have been found. A reduced microbial diversity is associated to inflammation, insulin-resistance, and adiposity. In particular, a rise in the Firmicutes/Bacteroidetes ratio is related to a low-grade inflammation and to an increased capability of harvesting energy from food. Interestingly, high-fat-diet favors the growth of bacteria capable of extracting more energy from food. Changes in some metabolites, such as short-chain fatty acids (SCFAs), produced by gut microbiota, and decreased amounts of the Akkermansia muciniphila are associated with the presence of type 2 diabetes. Among the mechanisms by which metformin acts on glucose metabolism and on the cardiovascular risk, some of them are due to positive effects on gut microbiota. A shift toward positive SCFAs produced by bacteria, an increase in some bacterial strains, including A. muciniphila, and some actions on bile acids mediated by microbiota have been described. All these recent advances have been reported and discussed." @default.
- W2947087777 created "2019-06-07" @default.
- W2947087777 creator A5015009718 @default.
- W2947087777 creator A5021348264 @default.
- W2947087777 creator A5025656026 @default.
- W2947087777 creator A5038827932 @default.
- W2947087777 creator A5066112696 @default.
- W2947087777 date "2019-12-01" @default.
- W2947087777 modified "2023-10-16" @default.
- W2947087777 title "The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases" @default.
- W2947087777 cites W1793035576 @default.
- W2947087777 cites W1971415551 @default.
- W2947087777 cites W1995265458 @default.
- W2947087777 cites W2000450805 @default.
- W2947087777 cites W2019145454 @default.
- W2947087777 cites W2074263634 @default.
- W2947087777 cites W2080578796 @default.
- W2947087777 cites W2086648828 @default.
- W2947087777 cites W2104890139 @default.
- W2947087777 cites W2112262623 @default.
- W2947087777 cites W2117616183 @default.
- W2947087777 cites W2159633664 @default.
- W2947087777 cites W2171016495 @default.
- W2947087777 cites W2173627324 @default.
- W2947087777 cites W2257654466 @default.
- W2947087777 cites W2428595929 @default.
- W2947087777 cites W2553515186 @default.
- W2947087777 cites W2559267012 @default.
- W2947087777 cites W2566304112 @default.
- W2947087777 cites W2617940752 @default.
- W2947087777 cites W2743743650 @default.
- W2947087777 cites W2768863811 @default.
- W2947087777 cites W2778672167 @default.
- W2947087777 cites W2797126474 @default.
- W2947087777 cites W2799640006 @default.
- W2947087777 cites W2801078802 @default.
- W2947087777 cites W2804795923 @default.
- W2947087777 cites W2809439583 @default.
- W2947087777 cites W2894133314 @default.
- W2947087777 cites W2897039855 @default.
- W2947087777 cites W2898587007 @default.
- W2947087777 cites W2907048060 @default.
- W2947087777 doi "https://doi.org/10.1016/j.coph.2019.03.011" @default.
- W2947087777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31015106" @default.
- W2947087777 hasPublicationYear "2019" @default.
- W2947087777 type Work @default.
- W2947087777 sameAs 2947087777 @default.
- W2947087777 citedByCount "166" @default.
- W2947087777 countsByYear W29470877772019 @default.
- W2947087777 countsByYear W29470877772020 @default.
- W2947087777 countsByYear W29470877772021 @default.
- W2947087777 countsByYear W29470877772022 @default.
- W2947087777 countsByYear W29470877772023 @default.
- W2947087777 crossrefType "journal-article" @default.
- W2947087777 hasAuthorship W2947087777A5015009718 @default.
- W2947087777 hasAuthorship W2947087777A5021348264 @default.
- W2947087777 hasAuthorship W2947087777A5025656026 @default.
- W2947087777 hasAuthorship W2947087777A5038827932 @default.
- W2947087777 hasAuthorship W2947087777A5066112696 @default.
- W2947087777 hasConcept C134018914 @default.
- W2947087777 hasConcept C203014093 @default.
- W2947087777 hasConcept C2775941767 @default.
- W2947087777 hasConcept C2776109033 @default.
- W2947087777 hasConcept C2776914184 @default.
- W2947087777 hasConcept C2777180221 @default.
- W2947087777 hasConcept C2777385719 @default.
- W2947087777 hasConcept C2777391703 @default.
- W2947087777 hasConcept C2777695942 @default.
- W2947087777 hasConcept C2780206646 @default.
- W2947087777 hasConcept C2780323712 @default.
- W2947087777 hasConcept C42062724 @default.
- W2947087777 hasConcept C511355011 @default.
- W2947087777 hasConcept C523546767 @default.
- W2947087777 hasConcept C539455810 @default.
- W2947087777 hasConcept C54355233 @default.
- W2947087777 hasConcept C555293320 @default.
- W2947087777 hasConcept C86803240 @default.
- W2947087777 hasConcept C89423630 @default.
- W2947087777 hasConceptScore W2947087777C134018914 @default.
- W2947087777 hasConceptScore W2947087777C203014093 @default.
- W2947087777 hasConceptScore W2947087777C2775941767 @default.
- W2947087777 hasConceptScore W2947087777C2776109033 @default.
- W2947087777 hasConceptScore W2947087777C2776914184 @default.
- W2947087777 hasConceptScore W2947087777C2777180221 @default.
- W2947087777 hasConceptScore W2947087777C2777385719 @default.
- W2947087777 hasConceptScore W2947087777C2777391703 @default.
- W2947087777 hasConceptScore W2947087777C2777695942 @default.
- W2947087777 hasConceptScore W2947087777C2780206646 @default.
- W2947087777 hasConceptScore W2947087777C2780323712 @default.
- W2947087777 hasConceptScore W2947087777C42062724 @default.
- W2947087777 hasConceptScore W2947087777C511355011 @default.
- W2947087777 hasConceptScore W2947087777C523546767 @default.
- W2947087777 hasConceptScore W2947087777C539455810 @default.
- W2947087777 hasConceptScore W2947087777C54355233 @default.
- W2947087777 hasConceptScore W2947087777C555293320 @default.
- W2947087777 hasConceptScore W2947087777C86803240 @default.
- W2947087777 hasConceptScore W2947087777C89423630 @default.
- W2947087777 hasLocation W29470877771 @default.