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- W2947127099 abstract "A Schiff base ligand 2-[(1 E )- N -{2-[(2-{( Z )-[1-(2-hydroxyphenyl) ethylidene] amino}ethyl)amino]ethyl}ethanimidoyl]phenol L was hydrolyzed by copper cation which lead to formation of 8,8-dichloro-2H,3H,5H,6H-1,3-diaza-2-cupracyclopenta[1,3-a]1,3-diaza-2-cupracyclopentane hydrate (Complex), characterized by UV, IR, Powder XRD and by elemental analysis. The study of quantum chemical calculations shown, stability and reducing character of L. In vitro antioxidant, anticoagulant, and hemolytic activities of L were evaluated. Antioxidant potential of L was assessed by DPPH scavenging, β-carotene bleaching test, hydroxyl radical scavenging method, ABTS radical scavenging test, and by reducing power test. In vitro anticoagulant effect of L at the 84 µg/mL, showed the maximum prolongation of plasma recalcification time. Schiff base L showed no toxic effect (hemolytic activity) in vitro. For anti-denaturation effect, L exhibited significant activity against denaturation of egg proteins with I% decreasing with increase of temperature. In conclusion, results of the present investigation indicate that the ligand L can be a potential anticoagulant and anti-denaturant agent." @default.
- W2947127099 created "2019-06-07" @default.
- W2947127099 creator A5019025079 @default.
- W2947127099 date "2018-07-25" @default.
- W2947127099 modified "2023-09-28" @default.
- W2947127099 title "Synthesis, Characterization and Crystal Structure of a New Schiff Base Ligand and Hydrolytic Cleavage of the Imine Bond Induced by a Copper(II) Cation" @default.
- W2947127099 hasPublicationYear "2018" @default.
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