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- W2947267513 abstract "During allergic reaction, nervous and immune systems mutually interact through release of mediators, including neurotrophic factors and nerve growth factor (NGF). These mediators modulate allergic reaction through binding their receptors expressed by immune and structural cells and by stimulating neuropeptide release by nerves. The role of neuropeptides and NGF has been demonstrated in allergic asthma and rhinitis, and, to a lesser extent, in allergic conjunctivitis. The aim of this review are to elucidate the evidence of the role of NGF and neuropeptides in the pathogenesis of allergic conjunctivitis.NGF modulates allergic reaction by stimulating release of cytokines, inflammatory mediators and neuropeptides by immune and structural cells and nerve endings at the site of inflammation. Evidence showed that local and systemic NGF levels increase in patients with allergic conjunctivitis, including allergic rhinoconjuncivitis, vernal keratoconjunctivitis and atopic keratoconjunctivitis. We recently described an increase of conjunctival p75NTR expression in patients with allergic rhinoconjuncivitis, and an increase of tear levels of NGF after conjunctival provocation test with allergen.NGF modulates ocular allergic reaction. Increasing understanding of the role of neuropeptides in allergic conjunctivitis may pave the way to the development of novel therapeutic approaches and improvement of patients' management." @default.
- W2947267513 created "2019-06-07" @default.
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- W2947267513 creator A5060504689 @default.
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- W2947267513 date "2019-10-01" @default.
- W2947267513 modified "2023-09-24" @default.
- W2947267513 title "Neurotrophic factors and nerve growth factor in ocular allergy" @default.
- W2947267513 cites W1484203480 @default.
- W2947267513 cites W1517991405 @default.
- W2947267513 cites W1964860618 @default.
- W2947267513 cites W1965020678 @default.
- W2947267513 cites W1965212424 @default.
- W2947267513 cites W1966516787 @default.
- W2947267513 cites W1969349734 @default.
- W2947267513 cites W1973664404 @default.
- W2947267513 cites W1978934062 @default.
- W2947267513 cites W1982769664 @default.
- W2947267513 cites W1984516568 @default.
- W2947267513 cites W1984754427 @default.
- W2947267513 cites W1985290325 @default.
- W2947267513 cites W1995474056 @default.
- W2947267513 cites W1997155157 @default.
- W2947267513 cites W1999666095 @default.
- W2947267513 cites W2003100003 @default.
- W2947267513 cites W2003284232 @default.
- W2947267513 cites W2006923280 @default.
- W2947267513 cites W2008664467 @default.
- W2947267513 cites W2015298630 @default.
- W2947267513 cites W2022711337 @default.
- W2947267513 cites W2023664228 @default.
- W2947267513 cites W2029328864 @default.
- W2947267513 cites W2035170553 @default.
- W2947267513 cites W2035976682 @default.
- W2947267513 cites W2039081678 @default.
- W2947267513 cites W2052442132 @default.
- W2947267513 cites W2052751137 @default.
- W2947267513 cites W2053048914 @default.
- W2947267513 cites W2054883211 @default.
- W2947267513 cites W2055067151 @default.
- W2947267513 cites W2056858516 @default.
- W2947267513 cites W2057377879 @default.
- W2947267513 cites W2057665491 @default.
- W2947267513 cites W2060277091 @default.
- W2947267513 cites W2060860188 @default.
- W2947267513 cites W2061819904 @default.
- W2947267513 cites W2064481223 @default.
- W2947267513 cites W2065011706 @default.
- W2947267513 cites W2067793380 @default.
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- W2947267513 cites W2078312786 @default.
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- W2947267513 cites W2278956043 @default.
- W2947267513 cites W2313289314 @default.
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- W2947267513 cites W2318073942 @default.
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- W2947267513 doi "https://doi.org/10.1097/aci.0000000000000555" @default.
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