Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947388263> ?p ?o ?g. }
- W2947388263 abstract "Purpose: Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and is a leading cause of disability in China. Acute exacerbations of COPD (AECOPD) are a leading cause of hospitalizations, and account for a substantial proportion of medical expenditure. Corticosteroids are commonly used to manage AECOPD in hospitalized patients, so our objective was to analyze the total medical expenditure associated with nebulized budesonide (nBUD) vs. systemic corticosteroids (SCS) in this population. Patients and methods: A post-hoc analysis was carried out in 1,577 and 973 patients diagnosed with COPD who had received any nBUD or SCS regimen for AECOPD during hospitalization, respectively. Regimens included monotherapy, sequential therapy, and sequential-combination therapy. Comparative total medical expenditure was analyzed using a generalized linear model controlling for age, gender, comorbidities, smoking history, and respiratory failure or pneumonia on admission. Results: The total medical expenditure per capita with any nBUD or SCS regimen was CN¥11,814 (US$1,922) and CN¥12,153 (US$1,977), respectively. Any nBUD regimen was associated with a significant saving of 5.1% in expenditure compared with any SCS regimen (P=0.0341). Comorbidities, Type II respiratory failure, or pneumonia were patient factors associated with higher total medical expenditure (P<0.0001). In a subgroup analysis of the patients who received monotherapy, total medical expenditure was CN¥10,900 (US$1,773) for nBUD and CN¥11,581 (US$1,884) for SCS; nBUD was associated with a significant saving of 8.7% in expenditure compared with SCS (P=0.0013). Similarly, in patients with respiratory failure, treatment with any nBUD regimen was associated with a 10.6% saving in expenditure over any SCS regimen (P=0.0239); however, the same comparison was not significant in patients without respiratory failure (3.4%; P=0.2299). Conclusion: AECOPD is a leading cause of hospitalization in China, which places substantial burden on the healthcare system. This post-hoc analysis suggests that nBUD regimens are associated with lower medical expenditure than SCS regimens in hospitalized patients with AECOPD, and may reduce the financial burden of COPD. However, prospective studies evaluating the effectiveness of nBUD therapies are warranted." @default.
- W2947388263 created "2019-06-07" @default.
- W2947388263 creator A5003628038 @default.
- W2947388263 creator A5009763324 @default.
- W2947388263 creator A5023687518 @default.
- W2947388263 creator A5054217629 @default.
- W2947388263 creator A5070085914 @default.
- W2947388263 date "2019-05-01" @default.
- W2947388263 modified "2023-09-28" @default.
- W2947388263 title "<p>Comparative analysis of medical expenditure with nebulized budesonide versus systemic corticosteroids in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease in China</p>" @default.
- W2947388263 cites W1909024616 @default.
- W2947388263 cites W1929470552 @default.
- W2947388263 cites W1931227931 @default.
- W2947388263 cites W1938285633 @default.
- W2947388263 cites W1960232152 @default.
- W2947388263 cites W1966771695 @default.
- W2947388263 cites W1982912113 @default.
- W2947388263 cites W1992802975 @default.
- W2947388263 cites W2006430543 @default.
- W2947388263 cites W2028425309 @default.
- W2947388263 cites W2033190938 @default.
- W2947388263 cites W2088061681 @default.
- W2947388263 cites W2106592700 @default.
- W2947388263 cites W2109475905 @default.
- W2947388263 cites W2110732884 @default.
- W2947388263 cites W2118942397 @default.
- W2947388263 cites W2121393149 @default.
- W2947388263 cites W2127951128 @default.
- W2947388263 cites W2150014574 @default.
- W2947388263 cites W2154146959 @default.
- W2947388263 cites W2159117980 @default.
- W2947388263 cites W23900508 @default.
- W2947388263 cites W2414321487 @default.
- W2947388263 cites W2462715422 @default.
- W2947388263 cites W2534110642 @default.
- W2947388263 cites W2538713347 @default.
- W2947388263 cites W2559067009 @default.
- W2947388263 cites W2741661620 @default.
- W2947388263 cites W2753051611 @default.
- W2947388263 cites W2781220280 @default.
- W2947388263 cites W2782983734 @default.
- W2947388263 cites W2796615944 @default.
- W2947388263 cites W2798095897 @default.
- W2947388263 cites W2801512047 @default.
- W2947388263 cites W2885109827 @default.
- W2947388263 cites W96340400 @default.
- W2947388263 doi "https://doi.org/10.2147/copd.s182015" @default.
- W2947388263 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6549719" @default.
- W2947388263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31213797" @default.
- W2947388263 hasPublicationYear "2019" @default.
- W2947388263 type Work @default.
- W2947388263 sameAs 2947388263 @default.
- W2947388263 citedByCount "2" @default.
- W2947388263 countsByYear W29473882632020 @default.
- W2947388263 countsByYear W29473882632021 @default.
- W2947388263 crossrefType "journal-article" @default.
- W2947388263 hasAuthorship W2947388263A5003628038 @default.
- W2947388263 hasAuthorship W2947388263A5009763324 @default.
- W2947388263 hasAuthorship W2947388263A5023687518 @default.
- W2947388263 hasAuthorship W2947388263A5054217629 @default.
- W2947388263 hasAuthorship W2947388263A5070085914 @default.
- W2947388263 hasBestOaLocation W29473882631 @default.
- W2947388263 hasConcept C126322002 @default.
- W2947388263 hasConcept C177713679 @default.
- W2947388263 hasConcept C187212893 @default.
- W2947388263 hasConcept C2776042228 @default.
- W2947388263 hasConcept C2776136866 @default.
- W2947388263 hasConcept C2776780178 @default.
- W2947388263 hasConcept C2777914695 @default.
- W2947388263 hasConcept C2781413609 @default.
- W2947388263 hasConcept C2908647359 @default.
- W2947388263 hasConcept C71924100 @default.
- W2947388263 hasConcept C99454951 @default.
- W2947388263 hasConceptScore W2947388263C126322002 @default.
- W2947388263 hasConceptScore W2947388263C177713679 @default.
- W2947388263 hasConceptScore W2947388263C187212893 @default.
- W2947388263 hasConceptScore W2947388263C2776042228 @default.
- W2947388263 hasConceptScore W2947388263C2776136866 @default.
- W2947388263 hasConceptScore W2947388263C2776780178 @default.
- W2947388263 hasConceptScore W2947388263C2777914695 @default.
- W2947388263 hasConceptScore W2947388263C2781413609 @default.
- W2947388263 hasConceptScore W2947388263C2908647359 @default.
- W2947388263 hasConceptScore W2947388263C71924100 @default.
- W2947388263 hasConceptScore W2947388263C99454951 @default.
- W2947388263 hasLocation W29473882631 @default.
- W2947388263 hasLocation W29473882632 @default.
- W2947388263 hasLocation W29473882633 @default.
- W2947388263 hasLocation W29473882634 @default.
- W2947388263 hasOpenAccess W2947388263 @default.
- W2947388263 hasPrimaryLocation W29473882631 @default.
- W2947388263 hasRelatedWork W2036613162 @default.
- W2947388263 hasRelatedWork W2077638660 @default.
- W2947388263 hasRelatedWork W2160736681 @default.
- W2947388263 hasRelatedWork W2230037512 @default.
- W2947388263 hasRelatedWork W2414385027 @default.
- W2947388263 hasRelatedWork W2466364785 @default.
- W2947388263 hasRelatedWork W2599609531 @default.
- W2947388263 hasRelatedWork W3202006358 @default.
- W2947388263 hasRelatedWork W4211261375 @default.
- W2947388263 hasRelatedWork W4226280427 @default.