FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2947442114> ?p ?o ?g. }

• W2947442114 abstract "Buprenorphine, used for opioid use disorder (OUD) treatment during pregnancy, provides unknown effects on maternal physiological activity. The primary aim of this report is to document acute effects of buprenorphine administration on indicators of maternal autonomic functioning. Effects of maternal buprenorphine dose and other substance exposures on maternal measures were examined, as were neonatal abstinence syndrome (NAS) outcomes.Forty-nine pregnant, buprenorphine-maintained women yielded maternal physiologic information (heart rate and variability, electrodermal activity, and respiratory rate) at 24, 28, 32 and 36 weeks gestation. Monitoring at trough and peak maternal medication levels was implemented to ascertain acute physiologic effects of buprenorphine administration.Buprenorphine administration accelerated maternal heart rate and reduced variability at two gestational ages (24 and 36 weeks) and suppressed sympathetic (electrodermal) activation at 24, 28 and 32 weeks at times of peak maternal medication levels. Maternal autonomic parameters were unrelated to polysubstance exposure with the exception of cigarette smoking. Heavier smoking dampened maternal heart rate variability across gestation and potentiated reactivity to buprenorphine at 24 and 36 weeks. Heavier smoking was also associated with reduced electrodermal activity at 36 weeks. Buprenorphine dose was unrelated to observed effects. Larger degree of maternal heart rate reactivity to buprenorphine administration was related to more severe NAS expression.These findings detail the maternal autonomic response to buprenorphine administration but also illustrate the significant effect of concurrent cigarette use on maternal autonomic regulation. This suggests the importance of smoking-reduction strategies in the comprehensive, medication-assisted treatment of women with OUD." @default.
• W2947442114 created "2019-06-07" @default.
• W2947442114 creator A5027021610 @default.
• W2947442114 creator A5037409685 @default.
• W2947442114 creator A5040974781 @default.
• W2947442114 creator A5049261515 @default.
• W2947442114 creator A5063086436 @default.
• W2947442114 creator A5083988524 @default.
• W2947442114 creator A5088592009 @default.
• W2947442114 date "2019-08-01" @default.
• W2947442114 modified "2023-10-03" @default.
• W2947442114 title "Maternal buprenorphine treatment during pregnancy and maternal physiology" @default.
• W2947442114 cites W1479887490 @default.
• W2947442114 cites W1984956006 @default.
• W2947442114 cites W1987739482 @default.
• W2947442114 cites W1991569159 @default.
• W2947442114 cites W1992389336 @default.
• W2947442114 cites W1993891717 @default.
• W2947442114 cites W1997014757 @default.
• W2947442114 cites W2009535056 @default.
• W2947442114 cites W2021633821 @default.
• W2947442114 cites W2025988777 @default.
• W2947442114 cites W2028326172 @default.
• W2947442114 cites W2032229595 @default.
• W2947442114 cites W2043776601 @default.
• W2947442114 cites W2054199095 @default.
• W2947442114 cites W2056264411 @default.
• W2947442114 cites W2097134928 @default.
• W2947442114 cites W2098684993 @default.
• W2947442114 cites W2140555176 @default.
• W2947442114 cites W2143144451 @default.
• W2947442114 cites W2333604794 @default.
• W2947442114 cites W2415521683 @default.
• W2947442114 cites W2423970421 @default.
• W2947442114 cites W2465699960 @default.
• W2947442114 cites W2485841659 @default.
• W2947442114 cites W2587611503 @default.
• W2947442114 cites W2632302589 @default.
• W2947442114 cites W2729435930 @default.
• W2947442114 cites W2752381490 @default.
• W2947442114 cites W2791800224 @default.
• W2947442114 cites W2887955765 @default.
• W2947442114 cites W2898561048 @default.
• W2947442114 doi "https://doi.org/10.1016/j.drugalcdep.2019.03.018" @default.
• W2947442114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31176949" @default.
• W2947442114 hasPublicationYear "2019" @default.
• W2947442114 type Work @default.
• W2947442114 sameAs 2947442114 @default.
• W2947442114 citedByCount "0" @default.
• W2947442114 crossrefType "journal-article" @default.
• W2947442114 hasAuthorship W2947442114A5027021610 @default.
• W2947442114 hasAuthorship W2947442114A5037409685 @default.
• W2947442114 hasAuthorship W2947442114A5040974781 @default.
• W2947442114 hasAuthorship W2947442114A5049261515 @default.
• W2947442114 hasAuthorship W2947442114A5063086436 @default.
• W2947442114 hasAuthorship W2947442114A5083988524 @default.
• W2947442114 hasAuthorship W2947442114A5088592009 @default.
• W2947442114 hasConcept C118552586 @default.
• W2947442114 hasConcept C126322002 @default.
• W2947442114 hasConcept C131872663 @default.
• W2947442114 hasConcept C170493617 @default.
• W2947442114 hasConcept C2777953023 @default.
• W2947442114 hasConcept C2778949969 @default.
• W2947442114 hasConcept C2779234561 @default.
• W2947442114 hasConcept C2780687700 @default.
• W2947442114 hasConcept C2781063702 @default.
• W2947442114 hasConcept C42219234 @default.
• W2947442114 hasConcept C42407357 @default.
• W2947442114 hasConcept C46973012 @default.
• W2947442114 hasConcept C54355233 @default.
• W2947442114 hasConcept C71924100 @default.
• W2947442114 hasConcept C84393581 @default.
• W2947442114 hasConcept C86803240 @default.
• W2947442114 hasConceptScore W2947442114C118552586 @default.
• W2947442114 hasConceptScore W2947442114C126322002 @default.
• W2947442114 hasConceptScore W2947442114C131872663 @default.
• W2947442114 hasConceptScore W2947442114C170493617 @default.
• W2947442114 hasConceptScore W2947442114C2777953023 @default.
• W2947442114 hasConceptScore W2947442114C2778949969 @default.
• W2947442114 hasConceptScore W2947442114C2779234561 @default.
• W2947442114 hasConceptScore W2947442114C2780687700 @default.
• W2947442114 hasConceptScore W2947442114C2781063702 @default.
• W2947442114 hasConceptScore W2947442114C42219234 @default.
• W2947442114 hasConceptScore W2947442114C42407357 @default.
• W2947442114 hasConceptScore W2947442114C46973012 @default.
• W2947442114 hasConceptScore W2947442114C54355233 @default.
• W2947442114 hasConceptScore W2947442114C71924100 @default.
• W2947442114 hasConceptScore W2947442114C84393581 @default.
• W2947442114 hasConceptScore W2947442114C86803240 @default.
• W2947442114 hasLocation W29474421141 @default.
• W2947442114 hasLocation W29474421142 @default.
• W2947442114 hasOpenAccess W2947442114 @default.
• W2947442114 hasPrimaryLocation W29474421141 @default.
• W2947442114 hasRelatedWork W2120298409 @default.
• W2947442114 hasRelatedWork W2186200056 @default.
• W2947442114 hasRelatedWork W2344177211 @default.
• W2947442114 hasRelatedWork W2409168192 @default.
• W2947442114 hasRelatedWork W2666548701 @default.
• W2947442114 hasRelatedWork W2947442114 @default.
• W2947442114 hasRelatedWork W3163987424 @default.

• next